PTF1A and ZW10

Number of citations of the paper that reports this interaction (PMID 25355311)
0

Data Source:
BioGRID (two hybrid)

		PTF1A	ZW10
Gene Name		pancreas specific transcription factor, 1a	zw10 kinetochore protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex Cytoplasm	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Kinetochore Microtubule Cytosol Membrane
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Chromatin Binding Sequence-specific DNA Binding Protein Dimerization Activity E-box Binding	Protein Binding Centromeric DNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Embryo Development Tissue Development Retina Layer Formation Cerebellum Development Pancreas Development Exocrine Pancreas Development Endocrine Pancreas Development Amacrine Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Retinoic Acid Receptor Signaling Pathway Neuron Fate Commitment Regulation Of Neural Retina Development	Mitotic Sister Chromatid Segregation Establishment Of Mitotic Spindle Orientation Mitotic Cell Cycle Protein Complex Assembly ER To Golgi Vesicle-mediated Transport Golgi Organization Mitotic Metaphase Plate Congression Mitotic Cell Cycle Checkpoint Regulation Of Exit From Mitosis Meiotic Nuclear Division Protein Transport Protein Localization To Kinetochore Cell Division
Pathways		Regulation of beta-cell development Regulation of gene expression in early pancreatic precursor cells	Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: AAMP CCDC27 CCNDBP1 KAT2B RBPJ RPGRIP1 SPATA7 TCF12 TCF4 TRIP12 ZW10	7 interactors: APP DCTN2 PTF1A RINT1 UBC ZWILCH ZWINT
Entrez ID		256297	9183
HPRD ID		09526	04902
Ensembl ID		ENSG00000168267	ENSG00000086827
Uniprot IDs		Q7RTS3	A1A528 O43264
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Gluconeogenesis Transcription Initiation From RNA Polymerase II Promoter Regulation Of Glycoprotein Biosynthetic Process DNA-templated Transcription, Initiation Positive Regulation Of Glucose Metabolic Process Myoblast Differentiation Regulation Of Gluconeogenesis Pituitary Gland Development Transcription From RNA Polymerase II Promoter Somatic Stem Cell Maintenance Regulation Of Cell Cycle Protein Localization To Photoreceptor Outer Segment Positive Regulation Of Canonical Wnt Signaling Pathway Involved In Cardiac Muscle Cell Fate Commitment Positive Regulation Of Ephrin Receptor Signaling Pathway Arterial Endothelial Cell Fate Commitment Epidermal Cell Fate Specification Protein Localization To Photoreceptor Connecting Cilium Regulation Of BMP Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Diencephalon Development Negative Regulation Of Cell Cycle Regulation Of Organ Growth Histone H3-K9 Acetylation Regulation Of Protein ADP-ribosylation Blood Vessel Lumenization Catenin Import Into Nucleus Blood Vessel Endothelial Cell Fate Specification Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Regulation Of Glucose Metabolic Process Muscle Structure Development Blood Vessel Development Protein Localization To Organelle Vasculature Development Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Negative Regulation Of Histone H2A K63-linked Ubiquitination Protein Localization To Nonmotile Primary Cilium N-terminal Peptidyl-lysine Acetylation Endothelial Cell Fate Specification Regulation Of Striated Muscle Tissue Development Notch Signaling Pathway Positive Regulation Of Transcription, DNA-templated Cell Cycle Regulation Of Histone Ubiquitination Negative Regulation Of Protein K63-linked Ubiquitination Maintenance Of DNA Repeat Elements Clara Cell Differentiation Cell Cycle Arrest Stem Cell Maintenance Regulation Of Carbohydrate Metabolic Process Interleukin-4 Secretion	Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Mitotic Cell Cycle Checkpoint Cell Cycle Intracellular Receptor Signaling Pathway Mitotic Cell Cycle Process Negative Regulation Of Mitotic Cell Cycle Cell Cycle Checkpoint Mitotic Cell Cycle Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Mitotic Nuclear Division Establishment Of Localization In Cell Cell Cycle Process Cellular Localization Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Cell Cycle Regulation Of ERBB Signaling Pathway Regulation Of Cell Cycle Process Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint G2/M Transition Of Mitotic Cell Cycle Synaptic Growth At Neuromuscular Junction Notch Signaling Pathway Collateral Sprouting In Absence Of Injury Regulation Of Neural Retina Development Collateral Sprouting Axon Midline Choice Point Recognition Amacrine Cell Differentiation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Axon Choice Point Recognition Antigen Processing And Presentation Of Peptide Antigen Regulation Of Cell Cycle Phase Transition Mitotic Cell Cycle Phase Transition Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Cycle Phase Transition Neuron Remodeling Exocrine Pancreas Development Positive Regulation Of Cell Cycle Antigen Processing And Presentation Positive Regulation Of Proteolysis Viral Protein Processing Regulation Of DNA Damage Checkpoint Regulation Of ER To Golgi Vesicle-mediated Transport
Tagcloud ?		anlage atohla augmentation cerebellar fertilization granule hepatocyte hpf inc klf8 kruppel lip met modulates morphants morpholino mosp neurobiol periodicals perturbed primordium purkinje rescued rhombic rhombomere substantially tectum wiley zebrafish	apparatus autophagy checkpoint comprises counterpart cytokinesis decay discuss dsl1 dsl3 endoplasmic endosome golgi intercorrelation metazoan moonlighting nag nrz participate reticulum retrograde rint1 sec39 summarize tethering tip20 trafficking transport vesicle
Tagcloud (Difference) ?		anlage atohla augmentation cerebellar fertilization granule hepatocyte hpf inc klf8 kruppel lip met modulates morphants morpholino mosp neurobiol periodicals perturbed primordium purkinje rescued rhombic rhombomere substantially tectum wiley zebrafish	apparatus autophagy checkpoint comprises counterpart cytokinesis decay discuss dsl1 dsl3 endoplasmic endosome golgi intercorrelation metazoan moonlighting nag nrz participate reticulum retrograde rint1 sec39 summarize tethering tip20 trafficking transport vesicle
Tagcloud (Intersection) ?