PTF1A and AAMP

Number of citations of the paper that reports this interaction (PubMedID 25355311)
39

Data Source:
BioGRID (two hybrid)

		PTF1A	AAMP
Description		pancreas associated transcription factor 1a	angio associated migratory cell protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex Cytoplasm	Cytoplasm Cytosol Plasma Membrane Cell Surface Microtubule Cytoskeleton Membrane Intercellular Bridge
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Sequence-specific DNA Binding Protein Dimerization Activity E-box Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Heparin Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Nervous System Development Tissue Development Retina Layer Formation Cerebellum Development Central Nervous System Neuron Differentiation Cell Differentiation Hindbrain Development Pancreas Development Exocrine Pancreas Development Developmental Process Amacrine Cell Differentiation Cell Fate Commitment Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Retinoic Acid Receptor Signaling Pathway Neuron Fate Commitment Generation Of Neurons Retina Morphogenesis In Camera-type Eye Regulation Of Neural Retina Development	Angiogenesis Positive Regulation Of Endothelial Cell Migration Smooth Muscle Cell Migration Cell Differentiation
Pathways		Regulation of gene expression in early pancreatic precursor cells Developmental Lineage of Pancreatic Acinar Cells	NOD1/2 Signaling Pathway Signaling by EGFR Signaling by VEGF Thromboxane signalling through TP receptor
Drugs
Diseases		Permanent neonatal diabetes mellitus (PNDM)
GWAS		Type 2 diabetes ( 32499647)	Basophil count ( 32888494) Inflammatory bowel disease ( 28067908) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Neutrophil count ( 32888494) Smooth-surface caries ( 23470693) Ulcerative colitis ( 21297633)
Interacting Genes		11 interacting genes: AAMP CCDC27 CCNDBP1 KAT2B RBPJ RPGRIP1 SPATA7 TCF12 TCF4 TRIP12 ZW10	12 interacting genes: BHLHE40 C8orf33 GABARAPL2 MAP1LC3B NELFCD NKAPD1 OGT PCAT1 PSEN2 PTF1A TK1 VPS52
Entrez ID		256297	14
HPRD ID		09526	04600
Ensembl ID		ENSG00000168267	ENSG00000127837
Uniprot IDs		Q7RTS3	C9JEH3 Q13685
PDB IDs
Enriched GO Terms of Interacting Partners?		Photoreceptor Distal Connecting Cilium Microtubule Cytoskeleton Transcription Regulator Complex Positive Regulation Of Ephrin Receptor Signaling Pathway DNA-binding Transcription Factor Binding Arterial Endothelial Cell Fate Commitment E-box Binding Regulation Of Attachment Of Spindle Microtubules To Kinetochore Protein Localization To Photoreceptor Connecting Cilium Photoreceptor Connecting Cilium Intercellular Bridge MAML1-RBP-Jkappa- ICN1 Complex Endocardium Morphogenesis Blood Vessel Endothelial Cell Fate Specification Blood Vessel Lumenization Auditory Receptor Cell Fate Commitment Regulation Of Cell Adhesion Involved In Heart Morphogenesis Positive Regulation Of Neuron Differentiation Beta-catenin-TCF7L2 Complex Negative Regulation Of RRNA Processing N-terminal Peptidyl-lysine Acetylation Diamine N-acetyltransferase Activity Regulation Of Embryonic Development Histone H3K9 Acetyltransferase Activity RZZ Complex Dsl1/NZR Complex Heterochromatin Boundary Formation Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Club Cell Differentiation Epidermal Cell Fate Specification Aortic Valve Development Pulmonary Valve Development Hair Follicle Maturation Regulation Of Generation Of Precursor Metabolites And Energy Endocardium Development DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Endothelial Cell Fate Specification Semi-lunar Valve Development TFIIB-class Transcription Factor Binding Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Sister Chromatid Segregation Regulation Of Ribosome Biogenesis Regulation Of Chromosome Segregation L-lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Negative Regulation Of Ribosome Biogenesis Positive Regulation Of Transcription By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Centromeric DNA Binding Axoneme Protein Localization To Ciliary Transition Zone	Mitophagy Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Macroautophagy Embryonic Ectodermal Digestive Tract Development Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Cellular Response To Nutrient Levels E-box Binding Autophagosome Membrane Autophagosome Maturation Negative Regulation Of Proteasomal Protein Catabolic Process Circadian Regulation Of Gene Expression Autophagy Thymidine Kinase Activity Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Autophagosome DNA Synthesis Involved In Mitotic DNA Replication Protein O-acetylglucosaminyltransferase Activity Autophagosome Assembly Regulation Of Neural Retina Development Mitochondrion-endoplasmic Reticulum Membrane Tethering Gamma-secretase Complex Regulation Of Calcium Import Into The Mitochondrion Aspartic Endopeptidase Activity, Intramembrane Cleaving GARP Complex EARP Complex Ectodermal Cell Differentiation Thymidine Metabolic Process Thymidine Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Negative Regulation Of Proteolysis Response To Nutrient Levels Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Negative Regulation Of Protein Catabolic Process Circadian Rhythm MRF Binding Phospholipid Binding Autophagosome Organization Protein-containing Complex Disassembly NELF Complex
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?