RNF144B and UBE2L6

Number of citations of the paper that reports this interaction (PMID 16427630)
13

Data Source:
HPRD (in vitro)

		RNF144B	UBE2L6
Gene Name		ring finger protein 144B	ubiquitin-conjugating enzyme E2L 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Ubiquitin Ligase Complex Cytoplasm Integral Component Of Membrane Mitochondrial Membrane	Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity	Ubiquitin-protein Transferase Activity Protein Binding Ligase Activity ISG15 Transferase Activity
	Biological Process	Apoptotic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process	Cellular Protein Modification Process Protein Ubiquitination Cytokine-mediated Signaling Pathway Modification-dependent Protein Catabolic Process ISG15-protein Conjugation Negative Regulation Of Type I Interferon Production Innate Immune Response
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System	RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways Antigen processing: Ubiquitination & Proteasome degradation Negative regulators of RIG-I/MDA5 signaling ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Class I MHC mediated antigen processing & presentation Antiviral mechanism by IFN-stimulated genes Adaptive Immune System Innate Immune System
Drugs
Diseases
GWAS		Endometriosis ( 23472165)
Protein-Protein Interactions		10 interactors: CDKN1A PAN2 UBE2I UBE2L3 UBE2L6 UBE2T UBE2U UBE2Z USP15 USP2	37 interactors: ARHGDIA ARIH1 ARIH2 CBLC DTX3 FLT3 LONRF1 MAP3K1 MUL1 PARK2 PJA2 RAD23A RBCK1 RBX1 RNF122 RNF125 RNF144A RNF144B RNF150 RNF19A RNF216 RNF25 RNF4 RNF40 RUNX1 SIAH1 SIAH2 SPEN TOPORS TRAF7 TRIM25 TRIM27 TRIM8 UBA6 UBA7 UBC UBE3A
Entrez ID		255488	9246
HPRD ID		17126	04867
Ensembl ID		ENSG00000137393	ENSG00000156587
Uniprot IDs		B4DZI2 Q7Z419	O14933
PDB IDs			1WZV 1WZW 2KJH
Enriched GO Terms of Interacting Partners?		Cellular Macromolecule Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Cellular Protein Modification Process Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Catabolic Process Cellular Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Proteolysis Protein Metabolic Process Protein K11-linked Ubiquitination Cellular Metabolic Process Positive Regulation Of SUMO Transferase Activity Histone H2B Conserved C-terminal Lysine Deubiquitination Regulation Of Type I Interferon Production Protein Deubiquitination Protein Modification By Small Protein Removal Positive Regulation Of Transferase Activity Cell Cycle Response To Glucocorticoid Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination Intestinal Epithelial Cell Maturation Response To Corticosteroid ISG15-protein Conjugation Regulation Of Proteasomal Protein Catabolic Process Cellular Response To UV-B Protein K6-linked Ubiquitination Innate Immune Response Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Monoubiquitinated Protein Deubiquitination Locomotor Rhythm Response To Stimulus Metabolic Process Cellular Response To DNA Damage Stimulus Stress-induced Premature Senescence Cell Cycle Phase Transition Cellular Response To Organic Substance Pathway-restricted SMAD Protein Phosphorylation Positive Regulation Of Cell Cycle Regulation Of Cellular Protein Metabolic Process Mitotic Cell Cycle Arrest Response To UV-B Intestinal Epithelial Cell Development	Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Protein Modification Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process Protein Metabolic Process Proteolysis Protein Polyubiquitination Catabolic Process Protein K48-linked Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Metabolic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Intracellular Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Metabolic Process Protein K63-linked Ubiquitination Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Signaling Protein Monoubiquitination Regulation Of Type I Interferon Production Negative Regulation Of Cytokine Production Negative Regulation Of Type I Interferon Production Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of I-kappaB Kinase/NF-kappaB Signaling Viral Process Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Signal Transduction Negative Regulation Of Viral Release From Host Cell Cellular Response To Stimulus Regulation Of Viral Release From Host Cell Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To Organic Substance Apoptotic Process Response To Stimulus Programmed Cell Death Regulation Of Cytokine Production Regulation Of Protein Ubiquitination Regulation Of Cellular Protein Metabolic Process Cell Death Regulation Of Kinase Activity Death Cellular Response To Cytokine Stimulus
Tagcloud ?			btbr c57blks db dba diabesity dissection hlbomdife hllt hyperglycaemia ifi202b inbred introgression jngj lean lep lepr lisch nzo ob obesity outcross pctp positional sorcs1 tallyho tbc1d1 tomosyn zealand zfp69
Tagcloud (Difference) ?			btbr c57blks db dba diabesity dissection hlbomdife hllt hyperglycaemia ifi202b inbred introgression jngj lean lep lepr lisch nzo ob obesity outcross pctp positional sorcs1 tallyho tbc1d1 tomosyn zealand zfp69
Tagcloud (Intersection) ?