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UBE2L6 and RNF19A
Number of citations of the paper that reports this interaction (PMID
11237715
)
10
Data Source:
HPRD
(in vivo)
UBE2L6
RNF19A
Gene Name
ubiquitin-conjugating enzyme E2L 6
ring finger protein 19A, RBR E3 ubiquitin protein ligase
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Cytoplasm
Centrosome
Integral Component Of Membrane
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
Ligase Activity
ISG15 Transferase Activity
Transcription Factor Binding
Zinc Ion Binding
Ligase Activity
Biological Process
Cellular Protein Modification Process
Protein Ubiquitination
Cytokine-mediated Signaling Pathway
Modification-dependent Protein Catabolic Process
ISG15-protein Conjugation
Negative Regulation Of Type I Interferon Production
Innate Immune Response
Microtubule Cytoskeleton Organization
Protein Ubiquitination
Pathways
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
Antigen processing: Ubiquitination & Proteasome degradation
Negative regulators of RIG-I/MDA5 signaling
ISG15 antiviral mechanism
Interferon Signaling
Cytokine Signaling in Immune system
Class I MHC mediated antigen processing & presentation
Antiviral mechanism by IFN-stimulated genes
Adaptive Immune System
Innate Immune System
Drugs
Diseases
GWAS
Atrioventricular conduction (
21041692
)
Protein-Protein Interactions
37 interactors:
ARHGDIA
ARIH1
ARIH2
CBLC
DTX3
FLT3
LONRF1
MAP3K1
MUL1
PARK2
PJA2
RAD23A
RBCK1
RBX1
RNF122
RNF125
RNF144A
RNF144B
RNF150
RNF19A
RNF216
RNF25
RNF4
RNF40
RUNX1
SIAH1
SIAH2
SPEN
TOPORS
TRAF7
TRIM25
TRIM27
TRIM8
UBA6
UBA7
UBC
UBE3A
16 interactors:
C11orf58
CASR
ILK
MAP3K7
NUDT21
RPS6KA5
SNCAIP
SOD1
SUFU
TUBG1
TUBG2
UBE2E2
UBE2L3
UBE2L6
VCP
ZAK
Entrez ID
9246
25897
HPRD ID
04867
06176
Ensembl ID
ENSG00000156587
ENSG00000034677
Uniprot IDs
O14933
Q9NV58
PDB IDs
1WZV
1WZW
2KJH
Enriched GO Terms of Interacting Partners
?
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Cellular Protein Modification Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Cellular Protein Metabolic Process
Cellular Macromolecule Catabolic Process
Protein Metabolic Process
Proteolysis
Protein Polyubiquitination
Catabolic Process
Protein K48-linked Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Cellular Metabolic Process
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Intracellular Signal Transduction
Regulation Of Signal Transduction
Metabolic Process
Protein K63-linked Ubiquitination
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Signaling
Protein Monoubiquitination
Regulation Of Type I Interferon Production
Negative Regulation Of Cytokine Production
Negative Regulation Of Type I Interferon Production
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Viral Process
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Signal Transduction
Negative Regulation Of Viral Release From Host Cell
Cellular Response To Stimulus
Regulation Of Viral Release From Host Cell
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cellular Response To Organic Substance
Apoptotic Process
Response To Stimulus
Programmed Cell Death
Regulation Of Cytokine Production
Regulation Of Protein Ubiquitination
Regulation Of Cellular Protein Metabolic Process
Cell Death
Regulation Of Kinase Activity
Death
Cellular Response To Cytokine Stimulus
Positive Regulation Of Protein Modification Process
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Positive Regulation Of Cellular Protein Metabolic Process
ISG15-protein Conjugation
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of MAP Kinase Activity
MAPK Cascade
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Transferase Activity
JNK Cascade
Cellular Response To Stress
Positive Regulation Of Protein Serine/threonine Kinase Activity
Positive Regulation Of Catalytic Activity
Signal Transduction By Phosphorylation
Regulation Of Protein Metabolic Process
Regulation Of MAP Kinase Activity
Positive Regulation Of Protein Phosphorylation
Microtubule Nucleation
Epithelial Tube Morphogenesis
Protein K11-linked Ubiquitination
Cellular Response To Organic Substance
Activation Of MAPK Activity
Response To Stress
Microtubule Polymerization
Tube Morphogenesis
Positive Regulation Of MAPK Cascade
Positive Regulation Of Phosphorylation
Positive Regulation Of Protein Kinase Activity
Vasodilation
Positive Regulation Of Kinase Activity
Cytoplasmic Microtubule Organization
Morphogenesis Of An Epithelium
Microtubule Polymerization Or Depolymerization
Regulation Of Cytokine Production
Protein Complex Assembly
Cell Cycle Process
Myelination In Peripheral Nervous System
Regulation Of Catalytic Activity
Protein Ubiquitination
Cellular Protein Modification Process
Regulation Of Protein Phosphorylation
Schwann Cell Development
Epithelium Development
Toll-like Receptor 5 Signaling Pathway
Protein Modification By Small Protein Conjugation
Toll-like Receptor 10 Signaling Pathway
Regulation Of MAPK Cascade
Cell Cycle Phase Transition
Response To Organic Substance
Tagcloud
?
btbr
c57blks
db
dba
diabesity
dissection
hlbomdife
hllt
hyperglycaemia
ifi202b
inbred
introgression
jngj
lean
lep
lepr
lisch
nzo
ob
obesity
outcross
pctp
positional
sorcs1
tallyho
tbc1d1
tomosyn
zealand
zfp69
Tagcloud (Difference)
?
btbr
c57blks
db
dba
diabesity
dissection
hlbomdife
hllt
hyperglycaemia
ifi202b
inbred
introgression
jngj
lean
lep
lepr
lisch
nzo
ob
obesity
outcross
pctp
positional
sorcs1
tallyho
tbc1d1
tomosyn
zealand
zfp69
Tagcloud (Intersection)
?