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UBE2L6 and RNF150
Number of citations of the paper that reports this interaction (PMID
19690564
)
33
Data Source:
BioGRID
(two hybrid)
UBE2L6
RNF150
Gene Name
ubiquitin-conjugating enzyme E2L 6
ring finger protein 150
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Integral Component Of Membrane
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
Ligase Activity
ISG15 Transferase Activity
Zinc Ion Binding
Biological Process
Cellular Protein Modification Process
Protein Ubiquitination
Cytokine-mediated Signaling Pathway
Modification-dependent Protein Catabolic Process
ISG15-protein Conjugation
Negative Regulation Of Type I Interferon Production
Innate Immune Response
Pathways
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
Antigen processing: Ubiquitination & Proteasome degradation
Negative regulators of RIG-I/MDA5 signaling
ISG15 antiviral mechanism
Interferon Signaling
Cytokine Signaling in Immune system
Class I MHC mediated antigen processing & presentation
Antiviral mechanism by IFN-stimulated genes
Adaptive Immune System
Innate Immune System
Drugs
Diseases
GWAS
Chronic obstructive pulmonary disease-related biomarkers (
23144326
)
Protein-Protein Interactions
37 interactors:
ARHGDIA
ARIH1
ARIH2
CBLC
DTX3
FLT3
LONRF1
MAP3K1
MUL1
PARK2
PJA2
RAD23A
RBCK1
RBX1
RNF122
RNF125
RNF144A
RNF144B
RNF150
RNF19A
RNF216
RNF25
RNF4
RNF40
RUNX1
SIAH1
SIAH2
SPEN
TOPORS
TRAF7
TRIM25
TRIM27
TRIM8
UBA6
UBA7
UBC
UBE3A
10 interactors:
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E3
UBE2L6
UBE2U
UBE2W
UBE2Z
Entrez ID
9246
57484
HPRD ID
04867
15258
Ensembl ID
ENSG00000156587
ENSG00000170153
Uniprot IDs
O14933
Q9ULK6
PDB IDs
1WZV
1WZW
2KJH
Enriched GO Terms of Interacting Partners
?
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Cellular Protein Modification Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Cellular Protein Metabolic Process
Cellular Macromolecule Catabolic Process
Protein Metabolic Process
Proteolysis
Protein Polyubiquitination
Catabolic Process
Protein K48-linked Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Cellular Metabolic Process
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Intracellular Signal Transduction
Regulation Of Signal Transduction
Metabolic Process
Protein K63-linked Ubiquitination
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Signaling
Protein Monoubiquitination
Regulation Of Type I Interferon Production
Negative Regulation Of Cytokine Production
Negative Regulation Of Type I Interferon Production
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Viral Process
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Signal Transduction
Negative Regulation Of Viral Release From Host Cell
Cellular Response To Stimulus
Regulation Of Viral Release From Host Cell
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cellular Response To Organic Substance
Apoptotic Process
Response To Stimulus
Programmed Cell Death
Regulation Of Cytokine Production
Regulation Of Protein Ubiquitination
Regulation Of Cellular Protein Metabolic Process
Cell Death
Regulation Of Kinase Activity
Death
Cellular Response To Cytokine Stimulus
Protein Polyubiquitination
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Cellular Protein Modification Process
Cellular Macromolecule Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Cellular Protein Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Proteolysis
Protein Metabolic Process
Protein Monoubiquitination
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Catabolic Process
Regulation Of DNA-templated Transcription In Response To Stress
ISG15-protein Conjugation
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Toll-like Receptor Signaling Pathway
Cellular Response To Oxygen Levels
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
Positive Regulation Of Innate Immune Response
Protein K63-linked Ubiquitination
Mitotic Spindle Assembly Checkpoint
Histone Ubiquitination
Spindle Assembly Checkpoint
Mitotic Spindle Checkpoint
Regulation Of Innate Immune Response
Negative Regulation Of Chromosome Segregation
Negative Regulation Of Type I Interferon Production
Spindle Checkpoint
Regulation Of Mitotic Sister Chromatid Separation
Negative Regulation Of Mitotic Nuclear Division
Cellular Response To Stress
Regulation Of Mitotic Metaphase/anaphase Transition
Response To Hypoxia
Cellular Metabolic Process
Tagcloud
?
btbr
c57blks
db
dba
diabesity
dissection
hlbomdife
hllt
hyperglycaemia
ifi202b
inbred
introgression
jngj
lean
lep
lepr
lisch
nzo
ob
obesity
outcross
pctp
positional
sorcs1
tallyho
tbc1d1
tomosyn
zealand
zfp69
Tagcloud (Difference)
?
btbr
c57blks
db
dba
diabesity
dissection
hlbomdife
hllt
hyperglycaemia
ifi202b
inbred
introgression
jngj
lean
lep
lepr
lisch
nzo
ob
obesity
outcross
pctp
positional
sorcs1
tallyho
tbc1d1
tomosyn
zealand
zfp69
Tagcloud (Intersection)
?