RNF144B and UBE2L3

Number of citations of the paper that reports this interaction (PMID 16427630)
13

Data Source:
HPRD (in vitro)

		RNF144B	UBE2L3
Gene Name		ring finger protein 144B	ubiquitin-conjugating enzyme E2L 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Ubiquitin Ligase Complex Cytoplasm Integral Component Of Membrane Mitochondrial Membrane	Ubiquitin Ligase Complex Nucleus Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity	Transcription Coactivator Activity Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ligase Activity Enzyme Binding Ubiquitin Protein Ligase Binding Poly(A) RNA Binding Ubiquitin Conjugating Enzyme Activity Ubiquitin-protein Transferase Activator Activity
	Biological Process	Apoptotic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process	Protein Polyubiquitination Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Cell Proliferation Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Cell Cycle Phase Transition Positive Regulation Of Ubiquitin-protein Transferase Activity Protein K11-linked Ubiquitination Cellular Response To Steroid Hormone Stimulus Cellular Response To Glucocorticoid Stimulus
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System	Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS		Endometriosis ( 23472165)	Celiac disease ( 20190752) Celiac disease and Rheumatoid arthritis ( 21383967) HDL cholesterol ( 20686565) Inflammatory bowel disease ( 23128233) Mean corpuscular volume ( 20139978) Red blood cell traits ( 23222517) Systemic lupus erythematosus ( 23273568 21408207 19838193)
Protein-Protein Interactions		10 interactors: CDKN1A PAN2 UBE2I UBE2L3 UBE2L6 UBE2T UBE2U UBE2Z USP15 USP2	64 interactors: ARIH1 ARIH2 ATXN3 BRCA1 CBL CBLC CCNB1IP1 CUL9 DTX3 FBXO2 FOS HACE1 HERC3 HSPA4 HUWE1 ITCH LIG4 MAPK6 MDM2 MID1 MKRN3 MUL1 NEDD4 NEDD4L NFKBIA NR3C1 PARK2 PJA1 POLR2A PTEN RAD23A RBCK1 RBX1 RELA RNF103 RNF113B RNF125 RNF144A RNF144B RNF19A RNF2 RNF216 SMAD4 SMAD7 SMURF1 SMURF2 STUB1 TRAF6 TRAF7 TRIM21 TRIM28 TRIM39 TRIP12 UBA1 UBA6 UBA7 UBASH3A UBC UBE3A UBE3C UBOX5 UBR5 WWP1 WWP2
Entrez ID		255488	7332
HPRD ID		17126	04762
Ensembl ID		ENSG00000137393	ENSG00000185651
Uniprot IDs		B4DZI2 Q7Z419	P68036
PDB IDs			1C4Z 1FBV 3SQV 3SY2
Enriched GO Terms of Interacting Partners?		Cellular Macromolecule Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Cellular Protein Modification Process Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Catabolic Process Cellular Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Proteolysis Protein Metabolic Process Protein K11-linked Ubiquitination Cellular Metabolic Process Positive Regulation Of SUMO Transferase Activity Histone H2B Conserved C-terminal Lysine Deubiquitination Regulation Of Type I Interferon Production Protein Deubiquitination Protein Modification By Small Protein Removal Positive Regulation Of Transferase Activity Cell Cycle Response To Glucocorticoid Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination Intestinal Epithelial Cell Maturation Response To Corticosteroid ISG15-protein Conjugation Regulation Of Proteasomal Protein Catabolic Process Cellular Response To UV-B Protein K6-linked Ubiquitination Innate Immune Response Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Monoubiquitinated Protein Deubiquitination Locomotor Rhythm Response To Stimulus Metabolic Process Cellular Response To DNA Damage Stimulus Stress-induced Premature Senescence Cell Cycle Phase Transition Cellular Response To Organic Substance Pathway-restricted SMAD Protein Phosphorylation Positive Regulation Of Cell Cycle Regulation Of Cellular Protein Metabolic Process Mitotic Cell Cycle Arrest Response To UV-B Intestinal Epithelial Cell Development	Protein Ubiquitination Protein Modification By Small Protein Conjugation Modification-dependent Protein Catabolic Process Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Protein Modification Process Cellular Macromolecule Catabolic Process Cellular Protein Metabolic Process Protein Polyubiquitination Proteolysis Protein Metabolic Process Catabolic Process Cellular Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Protein Ubiquitination Viral Process Regulation Of Protein Catabolic Process Cellular Response To Organic Substance Protein K63-linked Ubiquitination Negative Regulation Of Signal Transduction Protein K48-linked Ubiquitination Negative Regulation Of Signaling Protein Monoubiquitination Cellular Response To Stress Metabolic Process Protein Autoubiquitination Response To Stress Regulation Of Signal Transduction Intracellular Receptor Signaling Pathway Cellular Response To Stimulus Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Response To Organic Substance Response To Growth Factor Regulation Of Protein Metabolic Process Regulation Of Type I Interferon Production Regulation Of Signaling Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Cellular Metabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cytokine Production Response To Transforming Growth Factor Beta Cellular Response To DNA Damage Stimulus Regulation Of Transcription From RNA Polymerase II Promoter DNA Repair Positive Regulation Of Protein Catabolic Process
Tagcloud ?			2e37a 2e37b cav cav2 channel channels clathrin conjugating conserved dynamin inhibiting interact internalization involves lc1 light map1b mechanism microtubule prevented propose proteasome proteolytic q triggered ubiquitin ubiquitination variants
Tagcloud (Difference) ?			2e37a 2e37b cav cav2 channel channels clathrin conjugating conserved dynamin inhibiting interact internalization involves lc1 light map1b mechanism microtubule prevented propose proteasome proteolytic q triggered ubiquitin ubiquitination variants
Tagcloud (Intersection) ?