RNF144B

Name	ring finger protein 144B
Structure	No pdb structure
Novel Interactors	1 novel interactors: DTNBP1
Interactors	28 interactors: ANKS1A CDKN1A CHCHD2 CREB5 FOXH1 IL16 OTX1 PAN2 PAX5 PRKAB2 PROP1 PRR35 RIPPLY1 SGTA SGTB TRAF4 UBC UBE2I UBE2L3 UBE2L6 UBE2T UBE2U UBE2Z UBQLN1 USP15 USP2 VENTX ZIC1
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Cytoplasm Mitochondrion Cytosol Membrane Organelle Membrane Mitochondrial Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Ubiquitin Conjugating Enzyme Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Protein Ubiquitination Negative Regulation Of Apoptotic Process
Pathways	Antigen processing: Ubiquitination & Proteasome degradation
GWAS	Adult body size ( 32376654 ) Age at voice drop ( 27182965 ) Appendicular lean mass ( 33097823 ) Caudal middle frontal gyrus volume ( 31530798 ) Chronic periodontitis (mean interproximal clinical attachment level) ( 27601451 ) Chronotype ( 30696823 ) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098 ) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189 ) Endometriosis ( 23472165 ) Facial morphology ( 31763980 ) General risk tolerance (MTAG) ( 30643258 ) Gut microbiota relative abundance (Dorea) ( 33208821 ) Pulse pressure ( 30224653 ) Thiopurine S-methyltransferase activity ( 27770449 ) Triglyceride levels ( 32203549 )
Entrez ID	255488
HPRD ID	17126
Ensembl ID	ENSG00000137393
Uniprot IDs	Q7Z419
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Ubiquitin Conjugating Enzyme Activity Ubiquitin-like Protein Transferase Activity Nucleus Proteolysis Involved In Protein Catabolic Process Proteolysis TRC Complex Modification-dependent Protein Catabolic Process Macromolecule Catabolic Process Positive Regulation Of Metabolic Process Post-translational Protein Modification Positive Regulation Of Macromolecule Metabolic Process Ubiquitin Protein Ligase Binding Ubiquitin-dependent Protein Catabolic Process Nucleoplasm Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Modification By Small Protein Conjugation Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Regulation Of Primary Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of ERAD Pathway Pattern Specification Process Positive Regulation Of RNA Metabolic Process Protein Ubiquitination Cysteine-type Deubiquitinase Activity Regulation Of RNA Metabolic Process Regulation Of ERAD Pathway Catabolic Process Protein Binding Protein Modification Process Protein Targeting To ER Protein Polyubiquitination Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Cyclin Binding Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Establishment Of Protein Localization To Endoplasmic Reticulum Diencephalon Morphogenesis SUMO Conjugating Enzyme Activity Negative Regulation Of Store-operated Calcium Channel Activity Protein Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Response To Endoplasmic Reticulum Stress Protein K11-linked Ubiquitination