KCTD13 and KAT7

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KCTD13	KAT7
Description		potassium channel tetramerization domain containing 13	lysine acetyltransferase 7
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Nuclear Body Cul3-RING Ubiquitin Ligase Complex	Histone Acetyltransferase Complex Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm Cytosol Histone H3-K14 Acetyltransferase Complex Site Of DNA Damage
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Protein Domain Specific Binding Small GTPase Binding Identical Protein Binding	Chromatin Binding DNA Replication Origin Binding Transcription Coregulator Activity Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding Histone H3 Acetyltransferase Activity Histone H4 Acetyltransferase Activity Transferase Activity Acyltransferase Activity Histone H3K14 Acetyltransferase Activity Histone H3K23 Acetyltransferase Activity Histone H4K5 Acetyltransferase Activity Histone H4K8 Acetyltransferase Activity Histone H4K12 Acetyltransferase Activity Histone H3K4 Acetyltransferase Activity Metal Ion Binding Histone H4K16 Acetyltransferase Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Cell Migration Protein Ubiquitination Negative Regulation Of Rho Protein Signal Transduction Stress Fiber Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA Replication Positive Regulation Of Synaptic Transmission Protein Homooligomerization Neural Precursor Cell Proliferation	Regulation Of Cell Growth Natural Killer Cell Differentiation DNA Replication Regulation Of DNA Replication DNA Repair Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II DNA Damage Response Internal Peptidyl-lysine Acetylation Regulation Of DNA-templated DNA Replication Initiation T Cell Differentiation Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of DNA Replication Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Response To Sorbitol Response To Hydroxyurea Response To Actinomycin D Response To Dithiothreitol Response To Anisomycin DNA Replication-dependent Chromatin Disassembly Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Hematopoietic Stem Cell Proliferation Regulation Of DNA Biosynthetic Process Regulation Of Nucleotide-excision Repair
Pathways		RND3 GTPase cycle RND2 GTPase cycle	HATs acetylate histones
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Hand grip strength ( 29691431) Menarche (age at onset) ( 25231870) Schizophrenia ( 25056061 28991256 29483656 30285260) Urinary sodium excretion ( 31409800)	Mean corpuscular hemoglobin ( 27863252 29403010) Mean corpuscular volume ( 27863252 29403010) Mean reticulocyte volume ( 32888494)
Interacting Genes		20 interacting genes: ADRB2 ARMC7 CDC37 CDK2 CRK EXOSC5 FXR1 GORASP2 KAT7 LNX1 NTAQ1 NUDT18 PCNA POLD2 POLR1C PPARG PSMA1 RHOA VTA1 ZMYND19	45 interacting genes: APP AR ATN1 BARD1 BGLT3 CAAP1 CALCOCO2 CBX8 CDC6 CDK11B CEP126 CEP70 CSNK1E DDX11 DVL3 DYNC1I1 GMNN H2AC20 H3C1 H4C1 HAP1 HOOK2 ING4 KATNBL1 KCTD13 LRIF1 MAP2K1 MCM2 MCRS1 NINL ORC1 ORC2 PACSIN1 POLB PPID RGL2 RPS10 SAT1 SEPTIN5 SNAPIN TP53 VIM WDR33 ZBTB8A ZNF165
Entrez ID		253980	11143
HPRD ID		12339	07135
Ensembl ID		ENSG00000174943	ENSG00000136504
Uniprot IDs		A0A3B3IS45 Q8WZ19	A0A9L9PXR9 O95251
PDB IDs		4UIJ	5GK9 6MAJ 6MAK 7D0O 7D0P 7D0Q 7D0R 7D0S
Enriched GO Terms of Interacting Partners?		Positive Regulation Of DNA Replication DNA Replication Organelle Assembly DNA Strand Elongation Involved In DNA Replication Regulation Of Type II Interferon-mediated Signaling Pathway Regulation Of Response To Type II Interferon Cellular Response To Nitric Oxide Regulation Of DNA-templated DNA Replication Initiation Nucleobase-containing Compound Metabolic Process Nucleobase-containing Compound Biosynthetic Process Cellular Response To Oxygen-containing Compound Nucleic Acid Metabolic Process Regulation Of DNA Replication Cellular Response To Reactive Nitrogen Species Response To Nitric Oxide Negative Regulation Of Defense Response DNA Strand Elongation Translesion Synthesis Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Enzyme Binding Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Regulation Of Blood Pressure Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Mini Excitatory Postsynaptic Potential Angiotensin-mediated Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Mitotic Cleavage Furrow Formation Cyclin-dependent Protein Kinase Holoenzyme Complex PCNA Complex Replisome DNA Synthesis Involved In DNA Repair Postreplication Repair Negative Regulation Of Inflammatory Response Histone H3K23 Acetyltransferase Activity Histone H3K4 Acetyltransferase Activity Protein-N-terminal Glutamine Amidohydrolase Activity 8-hydroxy-dADP Phosphatase Activity 8-oxo-GDP Phosphatase Activity DGDP Catabolic Process DADP Catabolic Process DNA Metabolic Process DNA-templated Transcription Regulation Of Smooth Muscle Contraction Beta2-adrenergic Receptor Activity Aortic Valve Formation Negative Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Vascular Associated Smooth Muscle Contraction Cytosol Endothelial Tube Lumen Extension Regulation Of T Cell Migration Skeletal Muscle Satellite Cell Migration	DNA Replication Origin Binding Nucleus Regulation Of DNA Metabolic Process DNA Replication Initiation Regulation Of DNA Replication Nuclear Origin Of Replication Recognition Complex Chromatin Organization DNA Metabolic Process DNA Replication Chromatin Remodeling Centrosome Vesicle Transport Along Microtubule Cytoskeleton-dependent Intracellular Transport Cytoskeleton Vesicle Cytoskeletal Trafficking Regulation Of Cell Cycle G2/M Phase Transition Chromatin Binding Nucleoplasm Negative Regulation Of DNA Replication Regulation Of Nucleobase-containing Compound Metabolic Process DNA Repair Spindle Pole Regulation Of Cellular Response To Stress Organelle Transport Along Microtubule Transport Along Microtubule Regulation Of Cellular Component Organization Chromosome, Telomeric Region Origin Recognition Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Component Organization Organelle Organization Positive Regulation Of Chromatin Binding Negative Regulation Of Macromolecule Metabolic Process Establishment Of Vesicle Localization Microtubule-based Process Microtubule-based Transport Regulation Of Macromolecule Metabolic Process Protein Heterodimerization Activity Supramolecular Fiber Organization Mitotic DNA Replication Checkpoint Signaling Vesicle Localization Bergmann Glial Cell Differentiation Transcription Coactivator Binding Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Cell Cycle Chromosome Mitotic G2/M Transition Checkpoint Negative Regulation Of Metabolic Process Nuclear Matrix Regulation Of Primary Metabolic Process
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