KCTD13 and VTA1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KCTD13	VTA1
Gene Name		potassium channel tetramerization domain containing 13	vesicle (multivesicular body) trafficking 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cul3-RING Ubiquitin Ligase Complex	Cytosol Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Ubiquitin-protein Transferase Activity GTP-Rho Binding Protein Domain Specific Binding Identical Protein Binding	Protein Binding
	Biological Process	DNA Replication Cell Migration Protein Ubiquitination Negative Regulation Of Rho Protein Signal Transduction Stress Fiber Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA Replication Protein Homooligomerization	Protein Transport Viral Process Endosomal Transport Viral Life Cycle Membrane Organization
Pathways			HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS			Retinal vascular caliber ( 21060863)
Protein-Protein Interactions		13 interactors: ADRB2 ARMC7 CUL3 KAT7 LNX1 NUDT18 PCNA POLD2 PPARG RHOA TNFAIP1 VTA1 ZMYND19	17 interactors: APP CBS CDK4 CHMP5 DPPA2 KCTD13 KLHL12 LYST MAGEA11 MBIP NBR1 NECAB2 NGFRAP1 RABAC1 RPIA SSSCA1 ZBTB16
Entrez ID		253980	51534
HPRD ID		12339	09855
Ensembl ID		ENSG00000174943
Uniprot IDs		Q8WZ19	E7ETQ7 Q9NP79
PDB IDs			2LXL 2LXM
Enriched GO Terms of Interacting Partners?		DNA Replication Stress Fiber Assembly Regulation Of DNA Replication Nucleotide-excision Repair, DNA Gap Filling Telomere Maintenance Via Semi-conservative Replication Nuclear DNA Replication Negative Regulation Of Rho Protein Signal Transduction Telomere Maintenance Via Recombination Protein Complex Assembly Mitotic Recombination DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Cytokinesis Transcription-coupled Nucleotide-excision Repair Brown Fat Cell Differentiation Mitotic Cell Cycle Response To Cold Regulation Of Cytokinesis Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Small GTPase Mediated Signal Transduction Mismatch Repair Base-excision Repair Actin Filament Bundle Assembly Response To Metformin Low-density Lipoprotein Particle Receptor Biosynthetic Process DGDP Catabolic Process DADP Catabolic Process Negative Regulation Of Pancreatic Stellate Cell Proliferation Positive Regulation Of Deoxyribonuclease Activity Response To Diuretic GDP Catabolic Process Telomere Maintenance Nucleotide-excision Repair Chromosome Organization Cell Cycle Process Leading Strand Elongation Regulation Of Cholesterol Transporter Activity Cellular Response To Vitamin E Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Cellular Component Assembly DNA Metabolic Process DNA-dependent DNA Replication Negative Regulation Of Signal Transduction DNA Biosynthetic Process Actomyosin Structure Organization Ubiquitin-dependent Protein Catabolic Process Organelle Organization Modification-dependent Protein Catabolic Process Skeletal Muscle Satellite Cell Migration	Cell Division Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Mitotic Cell Cycle Phase Transition Lysosome Organization Positive Regulation Of Cell Cycle Phase Transition Cysteine Biosynthetic Process From Serine Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Homocysteine Catabolic Process Cysteine Biosynthetic Process Via Cystathionine Negative Regulation Of Cell Differentiation Organelle Organization Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Synaptic Growth At Neuromuscular Junction Mast Cell Secretory Granule Organization Transsulfuration Regulation Of Mitotic Cell Cycle Vacuole Organization Collateral Sprouting In Absence Of Injury Cysteine Biosynthetic Process L-cysteine Catabolic Process Hydrogen Sulfide Biosynthetic Process Positive Regulation Of Mitotic Cell Cycle L-serine Catabolic Process Pentose-phosphate Shunt, Non-oxidative Branch Regulation Of Cell Cycle Process Positive Regulation Of NK T Cell Differentiation Collateral Sprouting Axon Midline Choice Point Recognition Hydrogen Sulfide Metabolic Process Positive Regulation Of Peptidase Activity Endosome Transport Via Multivesicular Body Sorting Pathway Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Male Germ-line Stem Cell Asymmetric Division Regulation Of Cellular Protein Metabolic Process Axon Choice Point Recognition Protein Ubiquitination Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Cysteine Metabolic Process Secretion Of Lysosomal Enzymes Positive Regulation Of Cell Death Protein Modification By Small Protein Conjugation Regulation Of Response To Osmotic Stress Regulation Of Mitotic Spindle Assembly Regulation Of Signaling Homocysteine Metabolic Process Phospholipid Homeostasis Neuron Remodeling
Tagcloud ?			abscission atpase budding carboxyl cofactor compensatory coordinating cytokinesis endosomal enveloped escrt escrts helices hydrolysis input intergenic lip5 modulates multivesicular oligomer oligomerization rational sbp sorting stimulatory uncovered vps4 vse vsl
Tagcloud (Difference) ?			abscission atpase budding carboxyl cofactor compensatory coordinating cytokinesis endosomal enveloped escrt escrts helices hydrolysis input intergenic lip5 modulates multivesicular oligomer oligomerization rational sbp sorting stimulatory uncovered vps4 vse vsl
Tagcloud (Intersection) ?