SKAP2 and PRAM1

Number of citations of the paper that reports this interaction (PMID 11301322)
8

Data Source:
HPRD (in vivo)

		SKAP2	PRAM1
Gene Name		src kinase associated phosphoprotein 2	PML-RARA regulated adaptor molecule 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane
	Molecular Function	SH3/SH2 Adaptor Activity Protein Binding	Protein Binding Lipid Binding
	Biological Process	Protein Complex Assembly Signal Transduction Negative Regulation Of Cell Proliferation Positive Regulation Of Signal Transduction B Cell Activation
Pathways		Signal regulatory protein (SIRP) family interactions
Drugs
Diseases
GWAS			Height ( 18391951)
Protein-Protein Interactions		11 interactors: APP FASLG FYB FYN HCK KHDRBS1 LYN PRAM1 PTK2B SRC TGFBR1	19 interactors: A2M ABI2 APOE APP CCDC57 CDC37 FXR2 KRT40 LCP2 LYN MAST1 MXD1 NEK6 PSEN1 RNF32 SKAP1 SKAP2 TRIM27 UBE2E2
Entrez ID		8935	84106
HPRD ID		05558	05926
Ensembl ID		ENSG00000005020	ENSG00000133246
Uniprot IDs		B7Z5N4 B7Z5R3 O75563	Q96QH2
PDB IDs		3OMH
Enriched GO Terms of Interacting Partners?		Peptidyl-tyrosine Autophosphorylation Cell Surface Receptor Signaling Pathway Immune Response Protein Phosphorylation Immune System Process Protein Autophosphorylation Peptidyl-tyrosine Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Immune Response-activating Cell Surface Receptor Signaling Pathway Phosphorylation Cell Activation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Phosphatidylinositol 3-kinase Activity Locomotion Positive Regulation Of Signal Transduction Regulation Of Protein Metabolic Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Innate Immune Response Signal Transduction Regulation Of Apoptotic Process Cell Migration Response To Lipid Regulation Of Cell Proliferation Movement Of Cell Or Subcellular Component Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Fc-gamma Receptor Signaling Pathway Regulation Of Intracellular Transport Regulation Of Cell Death Enzyme Linked Receptor Protein Signaling Pathway Cell Motility Positive Regulation Of Immune System Process Signaling Immune Response-regulating Signaling Pathway Peptidyl-amino Acid Modification Regulation Of Cell Projection Organization Cell Communication Regulation Of Extrinsic Apoptotic Signaling Pathway Platelet Activation Regulation Of Phosphatidylinositol 3-kinase Activity Regulation Of Cellular Localization Regulation Of Signal Transduction Regulation Of Lipid Kinase Activity Cell Development Response To External Stimulus Leukocyte Migration Phosphate-containing Compound Metabolic Process Neuron Differentiation Wound Healing	Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Cellular Protein Metabolic Process Secretion By Cell Regulation Of Immune Response Negative Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Cytokine Secretion Establishment Of Localization In Cell Antigen Receptor-mediated Signaling Pathway Secretion Regulation Of Protein Metabolic Process Cell Activation Regulation Of Protein Kinase Activity Cellular Localization Negative Regulation Of Catalytic Activity Platelet Activation Regulation Of Kinase Activity Signal Transduction Negative Regulation Of Protein Kinase Activity Regulation Of Immune System Process Cellular Response To Stimulus Platelet Degranulation Negative Regulation Of Kinase Activity Regulation Of Cellular Process Regulation Of Signal Transduction Signaling Neuron Development Negative Regulation Of Cellular Metabolic Process Cell Communication Immune Response-activating Cell Surface Receptor Signaling Pathway Negative Regulation Of Transferase Activity Regulation Of Protein Phosphorylation Negative Regulation Of Protein Phosphorylation T Cell Receptor Signaling Pathway Regulation Of Signaling Regulation Of Proteolysis Neuron Differentiation Exocytosis Response To Wounding Protein Secretion Negative Regulation Of Immune Response Immune Response-regulating Cell Surface Receptor Signaling Pathway Cytokine Production Negative Regulation Of Phosphorylation Response To Stress Cellular Component Assembly Protein Localization Regulation Of Phosphorylation Regulation Of Cellular Component Organization Protein Metabolic Process
Tagcloud ?			2b4 acgh annotation c3h cd244 cnv congolense crosses damaging hej hybridisation infect lies livestock mbp plausible protozoan qtl resequencing sickness sleeping snp synonymous tir1 tir2 tir3 tir3c trypanosoma trypanosomes
Tagcloud (Difference) ?			2b4 acgh annotation c3h cd244 cnv congolense crosses damaging hej hybridisation infect lies livestock mbp plausible protozoan qtl resequencing sickness sleeping snp synonymous tir1 tir2 tir3 tir3c trypanosoma trypanosomes
Tagcloud (Intersection) ?