AIPL1 and TINF2

Number of citations of the paper that reports this interaction (PMID 21044950)
9

Data Source:
BioGRID (two hybrid)

		AIPL1	TINF2
Gene Name		aryl hydrocarbon receptor interacting protein-like 1	TERF1 (TRF1)-interacting nuclear factor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Photoreceptor Inner Segment Nucleus Cytoplasm	Chromosome, Telomeric Region Nuclear Telomere Cap Complex Nucleus Nucleoplasm Perinucleolar Chromocenter Nuclear Matrix
	Molecular Function	Farnesylated Protein Binding Protein Binding Unfolded Protein Binding	DNA Binding Protein Binding Telomeric DNA Binding
	Biological Process	Retina Homeostasis Protein Folding Visual Perception Phototransduction, Visible Light Protein Farnesylation Regulation Of CGMP Metabolic Process Negative Regulation Of Apoptotic Process	Telomere Maintenance Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Protein ADP-ribosylation Telomere Assembly Positive Regulation Of Telomere Maintenance Negative Regulation Of Telomere Maintenance Via Telomerase Protein Localization To Chromosome Negative Regulation Of Epithelial Cell Proliferation Protein Localization To Chromosome, Telomeric Region
Pathways			Telomere Maintenance Packaging Of Telomere Ends DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance Cellular Senescence Meiotic synapsis
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: ACD HSP90AA1 HSPA8 NUB1 POT1 TINF2	88 interactors: ACD ACOT7 ACTB ADA AFAP1L2 AIPL1 AK1 ANKMY2 ANXA4 ANXA5 APOBEC3F APPL2 ARHGDIA ARID3B BAG3 BIN2 CALD1 CCDC43 CCDC9 CKB CLK3 CPNE3 CRYGS CTTN DBN1 DCX DHFRL1 DPP3 EEF1D EIF4B ENO2 FAM131B FERMT3 FKBP6 GAPDH GNMT HNMT HOXA3 HSP90AB1 IPO5 KCTD17 LASP1 LDHA LGALSL LTA4H MAP2K3 NCDN NOL3 NUDC NUDCD2 OR2H1 PAGE2 PAK1IP1 PEX5 PFKP PGM1 PGM2 PHPT1 PKM POT1 PPP1R2 PPP6R3 PRKCB REM2 RGS14 RPSA SARS SCRN2 SIAH2 STUB1 SULT1C2 TAGLN TBL1X TERF1 TERF2 TOMM34 TPP1 TRIM15 TRIM16 TRIP10 TUBB TUBB4B TXNDC17 UCHL1 VIPR1 YWHAG ZFP36L1 ZNF790
Entrez ID		23746	26277
HPRD ID		05092	16056
Ensembl ID		ENSG00000129221	ENSG00000092330
Uniprot IDs		F1T0B6 Q6ZZB5 Q9NZN9	B4DFJ1 Q9BSI4
PDB IDs			3BQO 3BU8
Enriched GO Terms of Interacting Partners?		Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Negative Regulation Of DNA Replication Telomere Maintenance Telomere Capping Protein Localization To Chromosome, Telomeric Region Positive Regulation Of Telomerase Activity Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Telomere Maintenance Regulation Of DNA Replication Positive Regulation Of DNA Metabolic Process Regulation Of Telomerase Activity Positive Regulation Of Metabolic Process Positive Regulation Of DNA Biosynthetic Process Protein Refolding Regulation Of Chromosome Organization Protein Localization To Chromosome Regulation Of Cellular Response To Heat Telomere Maintenance Via Telomere Lengthening Regulation Of DNA Biosynthetic Process Cellular Response To Heat Positive Regulation Of DNA Replication Negative Regulation Of Biosynthetic Process Protein Localization To Organelle Negative Regulation Of Protein ADP-ribosylation Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation Negative Regulation Of Fibril Organization Response To Heat Response To Unfolded Protein Regulation Of Protein ADP-ribosylation Cellular Component Assembly Regulation Of Cellular Component Organization Regulation Of Fibril Organization Telomere Formation Via Telomerase Negative Regulation Of Cellular Metabolic Process Response To Temperature Stimulus Protein Import Into Mitochondrial Outer Membrane Negative Regulation Of Protein Glycosylation Regulation Of Metabolic Process Regulation Of Organelle Organization Clathrin Coat Disassembly Protection From Non-homologous End Joining At Telomere Cellular Localization Chromosome Organization	Negative Regulation Of Telomere Maintenance Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomerase Activity Glycolytic Process Protection From Non-homologous End Joining At Telomere Carbohydrate Catabolic Process Negative Regulation Of DNA Replication Telomere Assembly Catabolic Process Negative Regulation Of DNA Metabolic Process Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Catalytic Activity Positive Regulation Of Telomerase Activity Pyruvate Metabolic Process Telomere Maintenance Telomere Maintenance Via Telomerase Pathogenesis Generation Of Precursor Metabolites And Energy Glucose Metabolic Process Positive Regulation Of Single-stranded Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Negative Regulation Of Chromosome Organization Small Molecule Metabolic Process Organic Acid Metabolic Process Regulation Of DNA Biosynthetic Process Regulation Of Catalytic Activity Carboxylic Acid Metabolic Process Age-dependent Telomere Shortening Telomeric Loop Formation Nervous System Development Regulation Of Signaling Positive Regulation Of DNA Biosynthetic Process Glycogen Metabolic Process RNA-dependent DNA Replication Nucleoside Metabolic Process Telomere Maintenance Via Telomere Shortening Regulation Of Signal Transduction Hexose Metabolic Process Cellular Process Regulation Of DNA Replication Monocarboxylic Acid Metabolic Process Cellular Carbohydrate Metabolic Process Response To Stimulus Protein Localization To Chromosome Organelle Organization Telomere Maintenance Via Telomere Lengthening Polysaccharide Metabolic Process
Tagcloud ?		acuities acuity advancing amaurosis cep290 childhood corrected counseling crb1 crx departments exclusion gucy2d infancy lca lca5 leber multicentered ophthalmology participating pigmentosa rdh12 retinitis rp rpe65 rpgrip1 tulp1 visit visual	acd add broader clustered clustering convincingly correction cosegregated ends families fisher germline inactivating lod logarithm melanoma nonsense pot1 predispose probands q320x r364x shelterin tailed terf1 terf2 terf2ip yates
Tagcloud (Difference) ?		acuities acuity advancing amaurosis cep290 childhood corrected counseling crb1 crx departments exclusion gucy2d infancy lca lca5 leber multicentered ophthalmology participating pigmentosa rdh12 retinitis rp rpe65 rpgrip1 tulp1 visit visual	acd add broader clustered clustering convincingly correction cosegregated ends families fisher germline inactivating lod logarithm melanoma nonsense pot1 predispose probands q320x r364x shelterin tailed terf1 terf2 terf2ip yates
Tagcloud (Intersection) ?