ZBTB22 and DNAJA3

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ZBTB22	DNAJA3
Description		zinc finger and BTB domain containing 22	DnaJ heat shock protein family (Hsp40) member A3
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Actin Filament Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Neuromuscular Junction Mitochondrial Nucleoid Synapse Postsynaptic Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Signaling Receptor Binding Type II Interferon Receptor Binding Protein Binding ATP Binding Zinc Ion Binding Protein Kinase Binding Hsp70 Protein Binding GTPase Regulator Activity Heat Shock Protein Binding Protein-containing Complex Binding Metal Ion Binding NF-kappaB Binding Unfolded Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding IkappaB Kinase Complex Binding DNA-binding Transcription Factor Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Immune System Process Regulation Of Immune System Process Mitochondrial DNA Replication Protein Folding Apoptotic Process Activation-induced Cell Death Of T Cells Response To Stress Mitochondrion Organization Small GTPase-mediated Signal Transduction Neuromuscular Junction Development Negative Regulation Of Cell Population Proliferation Response To Heat Positive Regulation Of Protein Ubiquitination T Cell Differentiation In Thymus Response To Type II Interferon Positive Regulation Of T Cell Proliferation Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Canonical NF-kappaB Signal Transduction Protein Stabilization Negative Regulation Of Type II Interferon-mediated Signaling Pathway Skeletal Muscle Acetylcholine-gated Channel Clustering Cellular Senescence
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Walking pace ( 33128006)	Erectile dysfunction ( 30583798) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Immature fraction of reticulocytes ( 32888494) Schizophrenia ( 28991256) Triglyceride levels ( 32203549) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		16 interacting genes: AP4M1 CCDC13 DNAJA3 DRC4 FXR2 GABARAPL1 GATA1 MCRS1 MEMO1 MLLT6 PIN1 RBM39 TCEA2 UBQLN4 VAPA VAPB	47 interacting genes: ATOSB ATXN1 BRCA1 CACNA1C CARM1 CATSPERT CIDEB COIL CYSRT1 FAM131C FBXO7 FOSL2 FRMD6 FXR1 GCC1 GFI1B GRB2 HSPA1A HSPA8 IFNGR2 INPP5J JAK2 KDM1A KRAS LAMTOR5 MCPH1 MET MYO15B NFKBIA NFKBIB NOC4L NTRK1 OSGIN1 PRMT6 PTEN RAD51 RASA1 RELA RNF34 SHANK3 SMAD9 SMARCB1 STK16 TCF19 USP7 VHL ZBTB22
Entrez ID		9278	9093
HPRD ID		15761	09758
Ensembl ID		ENSG00000236104	ENSG00000103423
Uniprot IDs		A0A1U9X8V3 O15209	B3KM81 Q53G26 Q59E88 Q96EY1
PDB IDs			2CTT 2DN9 6IWS 7X89
Enriched GO Terms of Interacting Partners?		FFAT Motif Binding COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Endoplasmic Reticulum Localization Host-mediated Activation Of Viral Genome Replication Host-mediated Perturbation Of Viral Genome Replication Host-mediated Suppression Of Viral Genome Replication Organelle Organization Ciliary Basal Body Centriolar Satellite Viral Release From Host Cell Endoplasmic Reticulum Exit Site Vesicle Budding From Membrane Protein-membrane Adaptor Activity Host-mediated Activation Of Viral Process Beta-tubulin Binding Cis-trans Isomerase Activity	Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Enzyme Binding Regulation Of Cell Development Regulation Of Cell Differentiation Nucleoplasm Regulation Of RNA Metabolic Process Negative Regulation Of Programmed Cell Death Regulation Of Nucleobase-containing Compound Metabolic Process P53 Binding Regulation Of Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Identical Protein Binding Regulation Of Developmental Process Negative Regulation Of Apoptotic Process Positive Regulation Of RNA Metabolic Process Regulation Of Multicellular Organismal Development Positive Regulation Of RNA Biosynthetic Process Negative Regulation Of Intracellular Signal Transduction Protein-containing Complex Positive Regulation Of DNA-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Programmed Cell Death Histone H3R2 Methyltransferase Activity Positive Regulation Of Nervous System Development Positive Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Intracellular Signal Transduction Regulation Of Cellular Component Organization Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of Signal Transduction Ubiquitin Protein Ligase Binding Regulation Of Apoptotic Process Regulation Of Gene Expression Positive Regulation Of Cell Differentiation Histone Arginine N-methyltransferase Activity Regulation Of Nervous System Development Positive Regulation Of Transcription By RNA Polymerase II Response To Steroid Hormone Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Neurogenesis Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Macromolecule Metabolic Process Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Primary Metabolic Process
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