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SH3BP4 and CCT3
Number of citations of the paper that reports this interaction (PMID
18654987
)
7
Data Source:
BioGRID
(two hybrid)
SH3BP4
CCT3
Gene Name
SH3-domain binding protein 4
chaperonin containing TCP1, subunit 3 (gamma)
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Coated Pit
Clathrin-coated Vesicle
Extracellular Vesicular Exosome
Zona Pellucida Receptor Complex
Cytoplasm
Cytosol
Chaperonin-containing T-complex
Cytoskeleton
Microtubule
Plasma Membrane
Cell Body
Extracellular Vesicular Exosome
Molecular Function
GDP-dissociation Inhibitor Activity
Protein Binding
Ras GTPase Binding
Identical Protein Binding
Protein Binding
ATP Binding
Poly(A) RNA Binding
Unfolded Protein Binding
Biological Process
Endocytosis
Negative Regulation Of Cell Proliferation
Positive Regulation Of Autophagy
Negative Regulation Of Cell Growth
Negative Regulation Of TOR Signaling
Negative Regulation Of GTPase Activity
Amino Acid Import
Regulation Of Catalytic Activity
Protein Localization To Lysosome
Cellular Response To Amino Acid Stimulus
Protein Folding
Binding Of Sperm To Zona Pellucida
Cellular Protein Metabolic Process
Pore Complex Assembly
'de Novo' Posttranslational Protein Folding
Toxin Transport
Pathways
Cargo trafficking to the periciliary membrane
Protein folding
Organelle biogenesis and maintenance
Prefoldin mediated transfer of substrate to CCT/TriC
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding
Association of TriC/CCT with target proteins during biosynthesis
Chaperonin-mediated protein folding
Assembly of the primary cilium
BBSome-mediated cargo-targeting to cilium
Formation of tubulin folding intermediates by CCT/TriC
Folding of actin by CCT/TriC
Drugs
Diseases
GWAS
Dialysis-related mortality (
21546767
)
Orofacial clefts (
22419666
)
mean corpuscular hemoglobin concentration (
20139978
)
Subcutaneous adipose tissue (
22589738
)
Protein-Protein Interactions
21 interactors:
C2orf73
CCT3
CEP78
CIZ1
DNAJA4
FKBP4
GAPDHS
GKAP1
HSPA5
MPHOSPH8
MRGBP
NFU1
PLEKHA1
PRR14
PSMA1
TCP1
TTC1
TXNL1
YWHAE
YWHAG
ZBTB37
13 interactors:
EIF2B2
FANCA
HNRNPA0
HSPA8
MAPK6
MIPOL1
PAFAH1B2
RAF1
SH3BP4
SSSCA1
VAV2
VHL
XRCC6
Entrez ID
23677
7203
HPRD ID
09285
08969
Ensembl ID
ENSG00000130147
ENSG00000163468
Uniprot IDs
Q9P0V3
B3KX11
P49368
Q59H77
PDB IDs
Enriched GO Terms of Interacting Partners
?
Protein Folding
Toxin Transport
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Response To Heat
G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Cellular Response To Heat
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Binding Of Sperm To Zona Pellucida
Protein Localization
Substantia Nigra Development
Response To Temperature Stimulus
Sperm-egg Recognition
Steroid Hormone Receptor Complex Assembly
Regulation Of Protein Folding In Endoplasmic Reticulum
Translocation Of Peptides Or Proteins Into Host Cell Cytoplasm
Neural Nucleus Development
'de Novo' Posttranslational Protein Folding
Positive Regulation Of Mitochondrion Organization
'de Novo' Protein Folding
Cell-cell Recognition
Cellular Response To Heat
Negative Regulation Of Peptidyl-serine Dephosphorylation
Cerebellum Structural Organization
Regulation Of Heart Rate By Hormone
Mitotic Cell Cycle Process
Midbrain Development
Positive Regulation Of DNA-dependent DNA Replication Initiation
Mitotic Cell Cycle
Regulation Of Mitochondrion Organization
Cell Recognition
Single Fertilization
Regulation Of Apoptotic Process
Negative Regulation Of Protein Dephosphorylation
Positive Regulation Of Protein Ubiquitination
Regulation Of DNA-dependent DNA Replication Initiation
Cellular Response To Stress
Maintenance Of Protein Location In Cell
Regulation Of Cell Death
Positive Regulation Of Metabolic Process
Response To Stress
Positive Regulation Of Cellular Metabolic Process
Response To Abiotic Stimulus
Positive Regulation Of Autophagy
Nervous System Development
Death-inducing Signaling Complex Assembly
Negative Regulation Of Fibril Organization
Anatomical Structure Development
Response To Stimulus
Response To Organic Substance
Neurogenesis
Axon Guidance
Cellular Response To Stimulus
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of Autophagy
Posttranscriptional Regulation Of Gene Expression
Female Gonad Development
Cell Morphogenesis
Response To Heat
Development Of Primary Female Sexual Characteristics
Cellular Hyperosmotic Salinity Response
Regulation Of Fibril Organization
Developmental Process
System Development
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Axonogenesis
Regulation Of Metabolic Process
Clathrin Coat Disassembly
Axon Development
Cell Morphogenesis Involved In Neuron Differentiation
Cellular Response To X-ray
Chemotaxis
Defense Response
Neuron Projection Morphogenesis
Multicellular Organismal Development
Establishment Of Integrated Proviral Latency
Response To Temperature Stimulus
Negative Regulation Of Cell Proliferation
Platelet Activation
Cellular Hyperosmotic Response
Hyperosmotic Salinity Response
Establishment Of Viral Latency
Regulation Of Cell Proliferation
Cell Morphogenesis Involved In Differentiation
Neurotrophin TRK Receptor Signaling Pathway
3'-UTR-mediated MRNA Stabilization
Cellular Response To Stress
Neurotrophin Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Tagcloud
?
adequately
cct5
cct7
crc
csnk2a2
discover
discriminative
gna12
hypotheses
ifitm1
igfbp3
integrating
legacy
merely
merit
mutual
outlines
pdgfrb
plk1
proteomics
proxy
pruned
resultant
scheme
scoring
sized
subnetwork
subnetworks
wealth
Tagcloud (Difference)
?
adequately
cct5
cct7
crc
csnk2a2
discover
discriminative
gna12
hypotheses
ifitm1
igfbp3
integrating
legacy
merely
merit
mutual
outlines
pdgfrb
plk1
proteomics
proxy
pruned
resultant
scheme
scoring
sized
subnetwork
subnetworks
wealth
Tagcloud (Intersection)
?