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SH3BP4 and FKBP4
Number of citations of the paper that reports this interaction (PMID
18654987
)
7
Data Source:
BioGRID
(two hybrid)
SH3BP4
FKBP4
Gene Name
SH3-domain binding protein 4
FK506 binding protein 4, 59kDa
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Coated Pit
Clathrin-coated Vesicle
Extracellular Vesicular Exosome
Nucleoplasm
Cytoplasm
Mitochondrion
Endoplasmic Reticulum Membrane
Cytosol
Microtubule
Neuronal Cell Body
Axonal Growth Cone
Perinuclear Region Of Cytoplasm
Extracellular Vesicular Exosome
Molecular Function
GDP-dissociation Inhibitor Activity
Protein Binding
Ras GTPase Binding
Identical Protein Binding
Peptidyl-prolyl Cis-trans Isomerase Activity
Protein Binding
ATP Binding
GTP Binding
FK506 Binding
Protein Binding, Bridging
Heat Shock Protein Binding
Copper-dependent Protein Binding
Glucocorticoid Receptor Binding
Poly(A) RNA Binding
Tau Protein Binding
Phosphoprotein Binding
Biological Process
Endocytosis
Negative Regulation Of Cell Proliferation
Positive Regulation Of Autophagy
Negative Regulation Of Cell Growth
Negative Regulation Of TOR Signaling
Negative Regulation Of GTPase Activity
Amino Acid Import
Regulation Of Catalytic Activity
Protein Localization To Lysosome
Cellular Response To Amino Acid Stimulus
Protein Peptidyl-prolyl Isomerization
Protein Folding
Steroid Hormone Receptor Complex Assembly
Copper Ion Transport
Embryo Implantation
Negative Regulation Of Neuron Projection Development
Androgen Receptor Signaling Pathway
Prostate Gland Development
Negative Regulation Of Microtubule Polymerization Or Depolymerization
Negative Regulation Of Microtubule Polymerization
Protein Complex Localization
Cellular Response To Heat
Male Sex Differentiation
Chaperone-mediated Protein Folding
Regulation Of Cellular Response To Heat
Pathways
HSF1-dependent transactivation
Attenuation phase
Cellular response to heat stress
Drugs
Diseases
GWAS
Dialysis-related mortality (
21546767
)
Orofacial clefts (
22419666
)
Quantitative traits (
19197348
)
Protein-Protein Interactions
21 interactors:
C2orf73
CCT3
CEP78
CIZ1
DNAJA4
FKBP4
GAPDHS
GKAP1
HSPA5
MPHOSPH8
MRGBP
NFU1
PLEKHA1
PRR14
PSMA1
TCP1
TTC1
TXNL1
YWHAE
YWHAG
ZBTB37
25 interactors:
ACVR1
ATOX1
CALM1
CSNK2A1
EGFR
ESR1
FES
FKBP1A
GLMN
HSF1
HSP90AA1
HSPA4
IRF4
NR3C1
NR3C2
PHYH
PTPN2
S100A1
S100A2
S100A6
SH3BP4
SMURF2
SNCA
SQSTM1
STIP1
Entrez ID
23677
2288
HPRD ID
09285
11794
Ensembl ID
ENSG00000130147
Uniprot IDs
Q9P0V3
Q02790
PDB IDs
1N1A
1P5Q
1Q1C
1QZ2
4DRJ
4LAV
4LAW
4LAX
Enriched GO Terms of Interacting Partners
?
Protein Folding
Toxin Transport
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Response To Heat
G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Cellular Response To Heat
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Binding Of Sperm To Zona Pellucida
Protein Localization
Substantia Nigra Development
Response To Temperature Stimulus
Sperm-egg Recognition
Steroid Hormone Receptor Complex Assembly
Regulation Of Protein Folding In Endoplasmic Reticulum
Translocation Of Peptides Or Proteins Into Host Cell Cytoplasm
Neural Nucleus Development
'de Novo' Posttranslational Protein Folding
Positive Regulation Of Mitochondrion Organization
'de Novo' Protein Folding
Cell-cell Recognition
Cellular Response To Heat
Negative Regulation Of Peptidyl-serine Dephosphorylation
Cerebellum Structural Organization
Regulation Of Heart Rate By Hormone
Mitotic Cell Cycle Process
Midbrain Development
Positive Regulation Of DNA-dependent DNA Replication Initiation
Mitotic Cell Cycle
Regulation Of Mitochondrion Organization
Cell Recognition
Single Fertilization
Regulation Of Apoptotic Process
Negative Regulation Of Protein Dephosphorylation
Positive Regulation Of Protein Ubiquitination
Regulation Of DNA-dependent DNA Replication Initiation
Cellular Response To Stress
Maintenance Of Protein Location In Cell
Regulation Of Cell Death
Response To Organic Substance
Cellular Response To Organic Substance
Regulation Of Oxidoreductase Activity
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Response To Stimulus
Regulation Of Nitric-oxide Synthase Activity
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Metabolic Process
Regulation Of Reactive Oxygen Species Biosynthetic Process
Cellular Response To Stimulus
Cellular Response To Steroid Hormone Stimulus
Negative Regulation Of Signal Transduction
Regulation Of Signal Transduction
Response To Lipid
Cellular Response To Growth Factor Stimulus
Negative Regulation Of Signaling
Response To Organic Cyclic Compound
Response To Growth Factor
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Regulation Of Phospholipase Activity
Developmental Process
System Development
Positive Regulation Of Protein Metabolic Process
Cellular Response To Organic Cyclic Compound
Signaling
Regulation Of Signaling
Regulation Of Immune System Process
Cell Communication
Defense Response
Protein Import Into Mitochondrial Outer Membrane
Response To Steroid Hormone
Signal Transduction
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Oxidoreductase Activity
Response To Stress
Regulation Of Cell Proliferation
Positive Regulation Of Nitric Oxide Biosynthetic Process
Multicellular Organismal Development
Positive Regulation Of Reactive Oxygen Species Biosynthetic Process
Innate Immune Response
Cellular Response To Glucocorticoid Stimulus
Response To Glucocorticoid
Anatomical Structure Development
Cellular Response To Corticosteroid Stimulus
Regulation Of Reactive Oxygen Species Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Cellular Response To Hormone Stimulus
Regulation Of Immune Response
Response To Corticosteroid
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Tagcloud (Intersection)
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