SH3BP4 and DNAJA4

Number of citations of the paper that reports this interaction (PMID 18654987)
7

Data Source:
BioGRID (two hybrid)

		SH3BP4	DNAJA4
Gene Name		SH3-domain binding protein 4	DnaJ (Hsp40) homolog, subfamily A, member 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Coated Pit Clathrin-coated Vesicle Extracellular Vesicular Exosome	Cytosol Membrane
	Molecular Function	GDP-dissociation Inhibitor Activity Protein Binding Ras GTPase Binding Identical Protein Binding	Protein Binding ATP Binding Heat Shock Protein Binding Metal Ion Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Endocytosis Negative Regulation Of Cell Proliferation Positive Regulation Of Autophagy Negative Regulation Of Cell Growth Negative Regulation Of TOR Signaling Negative Regulation Of GTPase Activity Amino Acid Import Regulation Of Catalytic Activity Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus	Response To Heat Protein Refolding Negative Regulation Of Inclusion Body Assembly
Pathways
Drugs
Diseases
GWAS		Dialysis-related mortality ( 21546767) Orofacial clefts ( 22419666)
Protein-Protein Interactions		21 interactors: C2orf73 CCT3 CEP78 CIZ1 DNAJA4 FKBP4 GAPDHS GKAP1 HSPA5 MPHOSPH8 MRGBP NFU1 PLEKHA1 PRR14 PSMA1 TCP1 TTC1 TXNL1 YWHAE YWHAG ZBTB37	3 interactors: BANP ERG SH3BP4
Entrez ID		23677	55466
HPRD ID		09285	09920
Ensembl ID		ENSG00000130147	ENSG00000140403
Uniprot IDs		Q9P0V3	Q69YX3 Q8WW22
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Folding Toxin Transport Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Response To Heat G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Cellular Response To Heat Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Binding Of Sperm To Zona Pellucida Protein Localization Substantia Nigra Development Response To Temperature Stimulus Sperm-egg Recognition Steroid Hormone Receptor Complex Assembly Regulation Of Protein Folding In Endoplasmic Reticulum Translocation Of Peptides Or Proteins Into Host Cell Cytoplasm Neural Nucleus Development 'de Novo' Posttranslational Protein Folding Positive Regulation Of Mitochondrion Organization 'de Novo' Protein Folding Cell-cell Recognition Cellular Response To Heat Negative Regulation Of Peptidyl-serine Dephosphorylation Cerebellum Structural Organization Regulation Of Heart Rate By Hormone Mitotic Cell Cycle Process Midbrain Development Positive Regulation Of DNA-dependent DNA Replication Initiation Mitotic Cell Cycle Regulation Of Mitochondrion Organization Cell Recognition Single Fertilization Regulation Of Apoptotic Process Negative Regulation Of Protein Dephosphorylation Positive Regulation Of Protein Ubiquitination Regulation Of DNA-dependent DNA Replication Initiation Cellular Response To Stress Maintenance Of Protein Location In Cell Regulation Of Cell Death	Negative Regulation Of Potassium Ion Export Regulation Of Heart Rate By Hormone Regulation Of Heart Rate By Chemical Signal Peptidyl-histidine Phosphorylation Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Potassium Ion Export Protein Localization To Organelle Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Membrane Repolarization Negative Regulation Of Potassium Ion Transmembrane Transport Protein Localization To Lysosome Potassium Ion Homeostasis Phosphorelay Signal Transduction System Positive Regulation Of Potassium Ion Transmembrane Transport Ventricular Cardiac Muscle Cell Action Potential Negative Regulation Of Potassium Ion Transport Regulation Of Membrane Repolarization Regulation Of Heart Rate By Cardiac Conduction Cardiac Muscle Cell Action Potential Involved In Contraction Positive Regulation Of Potassium Ion Transport Negative Regulation Of TOR Signaling Negative Regulation Of GTPase Activity Membrane Depolarization During Action Potential Positive Regulation Of Autophagy Cardiac Muscle Cell Action Potential Regulation Of Potassium Ion Transmembrane Transport Regulation Of Cardiac Muscle Cell Contraction Cardiac Conduction Negative Regulation Of Ion Transmembrane Transport Cardiac Muscle Contraction Negative Regulation Of Transmembrane Transport Cellular Response To Drug Regulation Of TOR Signaling Regulation Of Potassium Ion Transport Cellular Response To Amino Acid Stimulus Heart Contraction Cellular Protein Localization Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Positive Regulation Of Ion Transmembrane Transport Striated Muscle Contraction Regulation Of Striated Muscle Contraction Action Potential Negative Regulation Of Ion Transport Regulation Of Autophagy
Tagcloud ?			adopted alignment atp6 classical cndp2 constructed csde1 csfv fancl fever gaining gopc hemorrhage hnrnph1 indications interactive library moap1 ncbi ns2 pnma1 regarded suvec swine switching tmed4 umbilical y2h
Tagcloud (Difference) ?			adopted alignment atp6 classical cndp2 constructed csde1 csfv fancl fever gaining gopc hemorrhage hnrnph1 indications interactive library moap1 ncbi ns2 pnma1 regarded suvec swine switching tmed4 umbilical y2h
Tagcloud (Intersection) ?