CCT3 and SSSCA1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		CCT3	SSSCA1
Gene Name		chaperonin containing TCP1, subunit 3 (gamma)	Sjogren syndrome/scleroderma autoantigen 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Zona Pellucida Receptor Complex Cytoplasm Cytosol Chaperonin-containing T-complex Cytoskeleton Microtubule Plasma Membrane Cell Body Extracellular Vesicular Exosome
	Molecular Function	Protein Binding ATP Binding Poly(A) RNA Binding Unfolded Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Protein Folding Binding Of Sperm To Zona Pellucida Cellular Protein Metabolic Process Pore Complex Assembly 'de Novo' Posttranslational Protein Folding Toxin Transport	Mitotic Nuclear Division Cell Division
Pathways		Cargo trafficking to the periciliary membrane Protein folding Organelle biogenesis and maintenance Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Association of TriC/CCT with target proteins during biosynthesis Chaperonin-mediated protein folding Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC
Drugs
Diseases
GWAS		mean corpuscular hemoglobin concentration ( 20139978) Subcutaneous adipose tissue ( 22589738)	Height ( 20881960)
Protein-Protein Interactions		13 interactors: EIF2B2 FANCA HNRNPA0 HSPA8 MAPK6 MIPOL1 PAFAH1B2 RAF1 SH3BP4 SSSCA1 VAV2 VHL XRCC6	20 interactors: ALS2CR11 C20orf195 CCDC33 CCNH CCT2 CCT3 CCT5 CCT7 FXR2 IL16 MYO15B NME6 NOC4L RNF115 SNAPC5 STAT3 SUMO1P1 TRAF3IP3 TRAPPC6A VTA1
Entrez ID		7203	10534
HPRD ID		08969	06921
Ensembl ID		ENSG00000163468	ENSG00000173465
Uniprot IDs		B3KX11 P49368 Q59H77	O60232
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Metabolic Process Response To Stress Positive Regulation Of Cellular Metabolic Process Response To Abiotic Stimulus Positive Regulation Of Autophagy Nervous System Development Death-inducing Signaling Complex Assembly Negative Regulation Of Fibril Organization Anatomical Structure Development Response To Stimulus Response To Organic Substance Neurogenesis Axon Guidance Cellular Response To Stimulus Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Autophagy Posttranscriptional Regulation Of Gene Expression Female Gonad Development Cell Morphogenesis Response To Heat Development Of Primary Female Sexual Characteristics Cellular Hyperosmotic Salinity Response Regulation Of Fibril Organization Developmental Process System Development Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Axonogenesis Regulation Of Metabolic Process Clathrin Coat Disassembly Axon Development Cell Morphogenesis Involved In Neuron Differentiation Cellular Response To X-ray Chemotaxis Defense Response Neuron Projection Morphogenesis Multicellular Organismal Development Establishment Of Integrated Proviral Latency Response To Temperature Stimulus Negative Regulation Of Cell Proliferation Platelet Activation Cellular Hyperosmotic Response Hyperosmotic Salinity Response Establishment Of Viral Latency Regulation Of Cell Proliferation Cell Morphogenesis Involved In Differentiation Neurotrophin TRK Receptor Signaling Pathway 3'-UTR-mediated MRNA Stabilization Cellular Response To Stress Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway	Toxin Transport Binding Of Sperm To Zona Pellucida Sperm-egg Recognition 'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Cell-cell Recognition Cell Recognition Single Fertilization Fertilization Protein Folding Sexual Reproduction Viral Process Reproduction Reproductive Process
Tagcloud ?		adequately cct5 cct7 crc csnk2a2 discover discriminative gna12 hypotheses ifitm1 igfbp3 integrating legacy merely merit mutual outlines pdgfrb plk1 proteomics proxy pruned resultant scheme scoring sized subnetwork subnetworks wealth
Tagcloud (Difference) ?		adequately cct5 cct7 crc csnk2a2 discover discriminative gna12 hypotheses ifitm1 igfbp3 integrating legacy merely merit mutual outlines pdgfrb plk1 proteomics proxy pruned resultant scheme scoring sized subnetwork subnetworks wealth
Tagcloud (Intersection) ?