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SH3BP4 and TXNL1
Number of citations of the paper that reports this interaction (PMID
18654987
)
7
Data Source:
BioGRID
(two hybrid)
SH3BP4
TXNL1
Gene Name
SH3-domain binding protein 4
thioredoxin-like 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Coated Pit
Clathrin-coated Vesicle
Extracellular Vesicular Exosome
Proteasome Complex
Nucleus
Cytoplasm
Extracellular Vesicular Exosome
Molecular Function
GDP-dissociation Inhibitor Activity
Protein Binding
Ras GTPase Binding
Identical Protein Binding
Protein Disulfide Oxidoreductase Activity
Disulfide Oxidoreductase Activity
Biological Process
Endocytosis
Negative Regulation Of Cell Proliferation
Positive Regulation Of Autophagy
Negative Regulation Of Cell Growth
Negative Regulation Of TOR Signaling
Negative Regulation Of GTPase Activity
Amino Acid Import
Regulation Of Catalytic Activity
Protein Localization To Lysosome
Cellular Response To Amino Acid Stimulus
Glycerol Ether Metabolic Process
Cell Redox Homeostasis
Oxidation-reduction Process
Pathways
Drugs
Diseases
GWAS
Dialysis-related mortality (
21546767
)
Orofacial clefts (
22419666
)
Protein-Protein Interactions
21 interactors:
C2orf73
CCT3
CEP78
CIZ1
DNAJA4
FKBP4
GAPDHS
GKAP1
HSPA5
MPHOSPH8
MRGBP
NFU1
PLEKHA1
PRR14
PSMA1
TCP1
TTC1
TXNL1
YWHAE
YWHAG
ZBTB37
4 interactors:
PSMC3
PSMD14
SH3BP4
SUMO4
Entrez ID
23677
9352
HPRD ID
09285
04335
Ensembl ID
ENSG00000130147
Uniprot IDs
Q9P0V3
O43396
PDB IDs
1GH2
1WWY
Enriched GO Terms of Interacting Partners
?
Protein Folding
Toxin Transport
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Response To Heat
G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Cellular Response To Heat
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Binding Of Sperm To Zona Pellucida
Protein Localization
Substantia Nigra Development
Response To Temperature Stimulus
Sperm-egg Recognition
Steroid Hormone Receptor Complex Assembly
Regulation Of Protein Folding In Endoplasmic Reticulum
Translocation Of Peptides Or Proteins Into Host Cell Cytoplasm
Neural Nucleus Development
'de Novo' Posttranslational Protein Folding
Positive Regulation Of Mitochondrion Organization
'de Novo' Protein Folding
Cell-cell Recognition
Cellular Response To Heat
Negative Regulation Of Peptidyl-serine Dephosphorylation
Cerebellum Structural Organization
Regulation Of Heart Rate By Hormone
Mitotic Cell Cycle Process
Midbrain Development
Positive Regulation Of DNA-dependent DNA Replication Initiation
Mitotic Cell Cycle
Regulation Of Mitochondrion Organization
Cell Recognition
Single Fertilization
Regulation Of Apoptotic Process
Negative Regulation Of Protein Dephosphorylation
Positive Regulation Of Protein Ubiquitination
Regulation Of DNA-dependent DNA Replication Initiation
Cellular Response To Stress
Maintenance Of Protein Location In Cell
Regulation Of Cell Death
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Signal Transduction Involved In DNA Damage Checkpoint
Signal Transduction Involved In Cell Cycle Checkpoint
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Ubiquitin-protein Transferase Activity
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Ubiquitin-protein Transferase Activity
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Positive Regulation Of Cell Cycle Arrest
Positive Regulation Of Ligase Activity
DNA Damage Response, Signal Transduction By P53 Class Mediator
Protein Modification By Small Protein Conjugation
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Signal Transduction In Response To DNA Damage
Mitotic DNA Damage Checkpoint
Regulation Of Cell Cycle Arrest
Mitotic DNA Integrity Checkpoint
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Protein Ubiquitination
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent
Signal Transduction By P53 Class Mediator
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Negative Regulation Of Catalytic Activity
Positive Regulation Of Canonical Wnt Signaling Pathway
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Protein Ubiquitination
Regulation Of Cell Cycle G1/S Phase Transition
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Cellular Protein Catabolic Process
DNA Damage Checkpoint
Positive Regulation Of Wnt Signaling Pathway
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle Checkpoint
Protein Polyubiquitination
Negative Regulation Of Signal Transduction
Negative Regulation Of Wnt Signaling Pathway
Regulation Of Protein Ubiquitination
Negative Regulation Of Signaling
Positive Regulation Of Protein Catabolic Process
Regulation Of Mitotic Cell Cycle Phase Transition
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