SH3BP4 and GKAP1

Number of citations of the paper that reports this interaction (PubMedID 18654987)
0

Data Source:
BioGRID (two hybrid)

		SH3BP4	GKAP1
Description		SH3 domain binding protein 4	G kinase anchoring protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Clathrin-coated Pit Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Extracellular Exosome	Golgi Apparatus
	Molecular Function	GDP-dissociation Inhibitor Activity Protein Binding Small GTPase Binding Identical Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Endocytosis Negative Regulation Of Cell Population Proliferation Positive Regulation Of Autophagy Negative Regulation Of Cell Growth Negative Regulation Of TOR Signaling Negative Regulation Of GTPase Activity Amino Acid Import Regulation Of Catalytic Activity Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus	Signal Transduction CGMP-mediated Signaling Positive Regulation Of Insulin Receptor Signaling Pathway
Pathways		Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Depression in smokers ( 30219690) Dialysis-related mortality ( 21546767) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Obstetric antiphospholipid syndrome ( 28424481) Orofacial clefts ( 22419666) Platelet count ( 32888494) Plateletcrit ( 32888494) Schizophrenia ( 34099189) Schizophrenia x sex interaction ( 34099189) Triglyceride levels in HIV infection ( 33109212)	Age at first sexual intercourse ( 34211149) Chronotype ( 30696823) Daytime nap ( 33568662) Eosinophil count ( 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Neutrophil percentage of granulocytes ( 27863252) Triglyceride levels ( 32154731)
Interacting Genes		23 interacting genes: CCT3 CEP78 CFTR CIMIP6 CIZ1 DNAJA4 EPS15 FKBP4 GAPDHS GKAP1 HSPA5 MPHOSPH8 MRGBP NFU1 PLEKHA1 PRR14 PSMA1 SNCA TCP1 TTC1 TXNL1 YWHAG ZBTB37	22 interacting genes: AP3B1 C1orf35 DHFR FAM124B FXR2 HDDC3 HGS HSD11B1 KANK2 KAT5 L3MBTL2 MFAP1 NDN PHOSPHO2 PRKG1 RCOR3 SDCBP SH3BP4 SOX18 UBQLN1 UBQLN4 ZCCHC10
Entrez ID		23677	80318
HPRD ID		09285	17042
Ensembl ID		ENSG00000130147	ENSG00000165113
Uniprot IDs		Q9P0V3	Q5VSY0
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Folding Unfolded Protein Binding ATP-dependent Protein Folding Chaperone Cytosol Protein Folding Chaperone Positive Regulation Of Telomerase RNA Localization To Cajal Body Positive Regulation Of Protein Localization To Cajal Body Zona Pellucida Receptor Complex Chaperonin-containing T-complex Heat Shock Protein Binding Regulation Of Telomerase RNA Localization To Cajal Body Positive Regulation Of Receptor Recycling Negative Regulation Of Microtubule Polymerization Protein-folding Chaperone Binding Positive Regulation Of Telomere Maintenance Via Telomerase Regulation Of Receptor Recycling Positive Regulation Of DNA Metabolic Process Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Protein Refolding Regulation Of Protein Localization Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Steroid Hormone Receptor Complex Assembly Negative Regulation Of Protein-containing Complex Assembly Phosphoprotein Binding Regulation Of Protein Folding In Endoplasmic Reticulum Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Binding Of Sperm To Zona Pellucida Sperm-egg Recognition H4/H2A Histone Acetyltransferase Complex ATP Hydrolysis Activity Negative Regulation Of Microtubule Polymerization Or Depolymerization Tau Protein Binding Maintenance Of Protein Localization In Organelle Regulation Of Protein Stability Protein Sequestering Activity Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of DNA Biosynthetic Process	Protein Localization To Vacuole Negative Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Protein Localization To Lysosome Establishment Of Protein Localization To Vacuole Protein Targeting To Vacuole Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Targeting Positive Regulation Of Exosomal Secretion Aggrephagy Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of Circadian Rhythm Regulation Of Exosomal Secretion Transcription Regulator Complex Epithelium Development Autophagy Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Metabolic Process Respiratory System Process Protein Targeting To Lysosome NADP Binding Response To Methotrexate Cortisol Dehydrogenase (NADP+) Activity 11-beta-hydroxysteroid Dehydrogenase (NADP+) Activity 7-beta-hydroxysteroid Dehydrogenase (NADP+) Activity Interleukin-5 Receptor Complex Vacuolar Transport Macroautophagy Histone H2AK5 Acetyltransferase Activity Regulation Of Autophagy Negative Regulation Of Double-strand Break Repair Negative Regulation Of Store-operated Calcium Channel Activity Polyubiquitin Modification-dependent Protein Binding Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase Activity Negative Regulation Of DNA Repair
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