CCT3 and BUD31

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		CCT3	BUD31
Description		chaperonin containing TCP1 subunit 3	BUD31 spliceosome associated protein
Image
GO Annotations	Cellular Component	Zona Pellucida Receptor Complex Cytoplasm Cytosol Chaperonin-containing T-complex Cytoskeleton Microtubule Cell Body Extracellular Exosome	Chromatin Nucleus Nucleoplasm Spliceosomal Complex Centrosome Microtubule Cytoskeleton U2-type Catalytic Step 2 Spliceosome
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Protein Folding Chaperone Unfolded Protein Binding ATP-dependent Protein Folding Chaperone	Transcription Coactivator Activity Protein Binding Nuclear Receptor Binding
	Biological Process	Protein Folding Binding Of Sperm To Zona Pellucida Positive Regulation Of Telomere Maintenance Via Telomerase Protein Stabilization Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Positive Regulation Of DNA-templated Transcription
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis BBSome-mediated cargo-targeting to cilium Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	mRNA Splicing - Major Pathway
Drugs		Phosphoaminophosphonic Acid-Adenylate Ester Artenimol
Diseases
GWAS		Basophil count ( 32888494) Glycated hemoglobin levels ( 24647736) Household income (MTAG) ( 31844048) Mean corpuscular hemoglobin concentration ( 20139978) Mean corpuscular volume ( 29403010) Red blood cell count ( 29403010) Red cell distribution width ( 32888494) Subcutaneous adipose tissue ( 22589738) Walking pace ( 33128006)	Facial emotion recognition (sad faces) ( 28608620) Serum metabolite levels ( 23093944)
Interacting Genes		26 interacting genes: BUD31 CEBPA DEPDC5 EIF2B2 ERBB2 FANCA GEMIN4 HNRNPA0 HSPA8 LINC01554 LNX2 MAPK6 MIPOL1 OGT PAFAH1B2 POLR1C PTEN RAF1 SH3BP4 SHANK3 SUMO2 UBE2Z VAV2 VHL XRCC6 ZNRD2	25 interacting genes: ADCY7 APP ATP13A1 BEND5 CCT3 CEBPA CTNNBL1 ERGIC3 HLA-A HOXA1 HTR5A KRTAP10-3 KRTAP10-7 MARCHF6 MEOX2 MMP24 NPC1 PANX1 PICK1 RELB RNF208 SCAF1 SF1 TMEM94 TSPAN7
Entrez ID		7203	8896
HPRD ID		08969	10351
Ensembl ID		ENSG00000163468	ENSG00000106245
Uniprot IDs		B3KX11 P49368 Q59H77	P41223
PDB IDs		6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8 7LUM 7LUP 7NVL 7NVM 7NVN 7NVO 7TRG 7TTN 7TTT 7TUB 7WU7 7WZ3 7X0A 7X0S 7X0V 7X3J 7X3U 7X6Q 7X7Y 8HKI 8I1U 8I6J 8I9U 8IB8 8SFE 8SFF 8SG8 8SG9 8SGC 8SGL 8SGQ 8SH9 8SHA 8SHD 8SHE 8SHF 8SHG 8SHL 8SHN 8SHO 8SHP 8SHQ 8SHT	4OED 4OH6 4OKB 5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM 7AAV 7ABF 7ABG 7ABI 7QTT 7W59 7W5A 7W5B 8C6J 8CH6 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8I0W 8Q7N 8QO9 8RO2 9FMD
Enriched GO Terms of Interacting Partners?		Protein Localization To Lysosome Positive Regulation Of Protein Metabolic Process Macromolecule Metabolic Process Protein Localization To Vacuole Postsynaptic Density Assembly ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Regulation Of TOR Signaling Glial Cell Development Postsynaptic Specialization Assembly Regulation Of Ubiquitin-dependent Protein Catabolic Process Nucleoplasm Positive Regulation Of Catabolic Process Positive Regulation Of Proteolysis Transcription By RNA Polymerase I Intracellular Signaling Cassette Regulation Of Protein Metabolic Process Regulation Of Cell Size Schwann Cell Development Myelination Axon Ensheathment Cytosol Postsynaptic Density Organization Dendritic Spine Morphogenesis Regulation Of TORC1 Signaling Negative Regulation Of TOR Signaling Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA-templated Transcription ERBB2 Signaling Pathway Regulation Of Translational Initiation Negative Regulation Of Cell Population Proliferation Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Postsynaptic Specialization Organization Identical Protein Binding Secretory Granule Lumen Intracellular Signal Transduction Ficolin-1-rich Granule Lumen Nucleus Cytoplasm Positive Regulation Of RNA Metabolic Process Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Biosynthetic Process Response To Stress Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Protein-containing Complex Assembly Positive Regulation Of Excitatory Postsynaptic Potential Dendritic Spine Organization Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
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