CCT3 and HNRNPA0

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		CCT3	HNRNPA0
Gene Name		chaperonin containing TCP1, subunit 3 (gamma)	heterogeneous nuclear ribonucleoprotein A0
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Zona Pellucida Receptor Complex Cytoplasm Cytosol Chaperonin-containing T-complex Cytoskeleton Microtubule Plasma Membrane Cell Body Extracellular Vesicular Exosome	Nucleus Nucleoplasm Ribonucleoprotein Complex
	Molecular Function	Protein Binding ATP Binding Poly(A) RNA Binding Unfolded Protein Binding	Nucleotide Binding RNA Binding AU-rich Element Binding Protein Kinase Binding Poly(A) RNA Binding
	Biological Process	Protein Folding Binding Of Sperm To Zona Pellucida Cellular Protein Metabolic Process Pore Complex Assembly 'de Novo' Posttranslational Protein Folding Toxin Transport	MRNA Splicing, Via Spliceosome MRNA Processing Inflammatory Response RNA Splicing Gene Expression Response To Lipopolysaccharide 3'-UTR-mediated MRNA Stabilization
Pathways		Cargo trafficking to the periciliary membrane Protein folding Organelle biogenesis and maintenance Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Association of TriC/CCT with target proteins during biosynthesis Chaperonin-mediated protein folding Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		mean corpuscular hemoglobin concentration ( 20139978) Subcutaneous adipose tissue ( 22589738)
Protein-Protein Interactions		13 interactors: EIF2B2 FANCA HNRNPA0 HSPA8 MAPK6 MIPOL1 PAFAH1B2 RAF1 SH3BP4 SSSCA1 VAV2 VHL XRCC6	15 interactors: CCT3 CIRBP DDX5 HNRNPF HNRNPH2 HNRNPH3 HNRNPK IL7R MAPK6 MAPKAPK2 MTNR1A MTNR1B NKX3-1 SRSF1 U2AF2
Entrez ID		7203	10949
HPRD ID		08969	17112
Ensembl ID		ENSG00000163468	ENSG00000177733
Uniprot IDs		B3KX11 P49368 Q59H77	Q13151
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Metabolic Process Response To Stress Positive Regulation Of Cellular Metabolic Process Response To Abiotic Stimulus Positive Regulation Of Autophagy Nervous System Development Death-inducing Signaling Complex Assembly Negative Regulation Of Fibril Organization Anatomical Structure Development Response To Stimulus Response To Organic Substance Neurogenesis Axon Guidance Cellular Response To Stimulus Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Autophagy Posttranscriptional Regulation Of Gene Expression Female Gonad Development Cell Morphogenesis Response To Heat Development Of Primary Female Sexual Characteristics Cellular Hyperosmotic Salinity Response Regulation Of Fibril Organization Developmental Process System Development Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Axonogenesis Regulation Of Metabolic Process Clathrin Coat Disassembly Axon Development Cell Morphogenesis Involved In Neuron Differentiation Cellular Response To X-ray Chemotaxis Defense Response Neuron Projection Morphogenesis Multicellular Organismal Development Establishment Of Integrated Proviral Latency Response To Temperature Stimulus Negative Regulation Of Cell Proliferation Platelet Activation Cellular Hyperosmotic Response Hyperosmotic Salinity Response Establishment Of Viral Latency Regulation Of Cell Proliferation Cell Morphogenesis Involved In Differentiation Neurotrophin TRK Receptor Signaling Pathway 3'-UTR-mediated MRNA Stabilization Cellular Response To Stress Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing Regulation Of RNA Splicing Regulation Of MRNA Stability Regulation Of RNA Stability Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Gene Expression MRNA Stabilization Positive Regulation Of Gene Expression RNA Metabolic Process Termination Of RNA Polymerase II Transcription Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Response To DNA Damage Stimulus MRNA Export From Nucleus Regulation Of Gene Expression DNA-templated Transcription, Termination RNA Export From Nucleus MRNA 3'-end Processing Interleukin-7-mediated Signaling Pathway Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Androgen Secretion Regulation Of Lipid Transport Transcription From RNA Polymerase II Promoter Negative Regulation Of Estrogen Receptor Binding RNA 3'-end Processing Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Posttranscriptional Regulation Of Gene Expression Nuclear Export MRNA Transport Regulation Of Response To DNA Damage Stimulus MRNA 5'-splice Site Recognition Negative Regulation Of T Cell Mediated Cytotoxicity Nucleobase-containing Compound Metabolic Process RNA Transport Cell Growth G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger RNA Localization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Macropinocytosis Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Negative Regulation Of Receptor Binding
Tagcloud ?		adequately cct5 cct7 crc csnk2a2 discover discriminative gna12 hypotheses ifitm1 igfbp3 integrating legacy merely merit mutual outlines pdgfrb plk1 proteomics proxy pruned resultant scheme scoring sized subnetwork subnetworks wealth	atr cdc25b checkpoint chk1 contributions cytoplasm defective dissect entry feedback gadd45alpha genetics genotoxic initiate mitotic mk2 p38 parn phosphorylates posttranscriptional releases relocalizes rewire sequestration stabilization stabilize sustaining tiar unrepaired
Tagcloud (Difference) ?		adequately cct5 cct7 crc csnk2a2 discover discriminative gna12 hypotheses ifitm1 igfbp3 integrating legacy merely merit mutual outlines pdgfrb plk1 proteomics proxy pruned resultant scheme scoring sized subnetwork subnetworks wealth	atr cdc25b checkpoint chk1 contributions cytoplasm defective dissect entry feedback gadd45alpha genetics genotoxic initiate mitotic mk2 p38 parn phosphorylates posttranscriptional releases relocalizes rewire sequestration stabilization stabilize sustaining tiar unrepaired
Tagcloud (Intersection) ?