IPO5 and RPS7

Number of citations of the paper that reports this interaction (PMID 9687515)
135

Data Source:
HPRD (in vitro)

		IPO5	RPS7
Gene Name		importin 5	ribosomal protein S7
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Pore Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Membrane Nuclear Membrane Intracellular Membrane-bounded Organelle	Nucleus Nucleolus Cytoplasm Microtubule Organizing Center Cytosol Ribosome Focal Adhesion Membrane Cytosolic Small Ribosomal Subunit Ribonucleoprotein Complex 90S Preribosome Small-subunit Processome Extracellular Vesicular Exosome
	Molecular Function	GTPase Inhibitor Activity Protein Binding Ran GTPase Binding Protein Transporter Activity Poly(A) RNA Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding
	Biological Process	NLS-bearing Protein Import Into Nucleus Ribosomal Protein Import Into Nucleus Viral Process Positive Regulation Of Protein Import Into Nucleus Negative Regulation Of Catalytic Activity Cellular Response To Amino Acid Stimulus	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation RRNA Processing Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Ribosomal Small Subunit Biogenesis Cellular Protein Metabolic Process
Pathways		Influenza Viral RNA Transcription and Replication Influenza Infection Influenza Life Cycle vRNP Assembly	Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: ACD BHLHB9 DPPA3 DTNBP1 H1F0 NUP153 NUP214 NUP62 NUP98 RAG2 RAN RANBP2 RPL13 RPL23 RPL23A RPL5 RPL7 RPS7 SRP19 TERF1 TINF2 WASL	9 interactors: CDKN2A IPO5 IPO7 MDM2 NEK6 RPS4X TNPO1 UPF2 ZBTB14
Entrez ID		3843	6201
HPRD ID		03597	04712
Ensembl ID		ENSG00000065150	ENSG00000171863
Uniprot IDs		B3KWG6 O00410 Q9BVS9	P62081
PDB IDs			3J3A
Enriched GO Terms of Interacting Partners?		Viral Transcription Viral Life Cycle Protein Localization To Organelle Membrane Organization Establishment Of Protein Localization To Organelle Cytoplasmic Transport Viral Process Protein Targeting Intracellular Transport Protein Localization Cellular Localization Establishment Of Localization In Cell Cellular Protein Localization Protein Transport SRP-dependent Cotranslational Protein Targeting To Membrane Establishment Of Protein Localization Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Intracellular Protein Transport Protein Localization To Endoplasmic Reticulum Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Protein Targeting To Membrane Cellular Nitrogen Compound Metabolic Process Mitotic Nuclear Envelope Disassembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nuclear Envelope Disassembly Nitrogen Compound Metabolic Process Establishment Of Protein Localization To Membrane Nuclear Import Nucleocytoplasmic Transport Nuclear Transport Translational Termination Nuclear-transcribed MRNA Catabolic Process Nuclear Envelope Organization Glucose Transport MRNA Catabolic Process Hexose Transport Translational Elongation Negative Regulation Of Telomere Maintenance Via Telomerase RNA Catabolic Process Cellular Protein Complex Disassembly Protein Localization To Membrane Protein Complex Disassembly Regulation Of Glucose Transport Organelle Organization Translational Initiation Negative Regulation Of Telomere Maintenance	Protein Localization To Nucleus Protein Localization To Organelle Viral Process Nucleocytoplasmic Transport Nuclear Transport Cytoplasmic Transport Establishment Of Protein Localization To Organelle Protein Import Into Nucleus Nuclear Import Protein Targeting Protein Import Protein Destabilization Regulation Of Cellular Senescence Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Nucleocytoplasmic Transport Regulation Of Protein Export From Nucleus Cellular Protein Localization Regulation Of Mitotic Cell Cycle Phase Transition Cellular Localization Regulation Of Cell Cycle Phase Transition Establishment Of Protein Localization Regulation Of Intracellular Protein Transport Intracellular Transport Regulation Of Signal Transduction By P53 Class Mediator Intracellular Protein Transport Protein Localization Positive Regulation Of Cell Cycle Arrest Cellular Response To UV-C Cellular Response To Vitamin B1 Establishment Of Localization In Cell Regulation Of Mitotic Cell Cycle Regulation Of Intracellular Transport Posttranscriptional Regulation Of Gene Expression Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Cell Cycle Arrest Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Cell Cycle Process Regulation Of Response To DNA Damage Stimulus Senescence-associated Heterochromatin Focus Assembly Protein Transport Regulation Of Protein Stability Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Transport Nuclear-transcribed MRNA Catabolic Process Positive Regulation Of Intracellular Protein Transport Traversing Start Control Point Of Mitotic Cell Cycle Positive Regulation Of Cellular Senescence DNA Damage Checkpoint MRNA Catabolic Process Regulation Of Proteolysis
Tagcloud ?		apex1 apurine apyrimidine brg1 coherently depict endonuclease escs h2a impalpha4 importin indefinitely macro nono npm1 npr nucleoplasmin octamer pdcd5 pou renew renewal ribonucleoprotein roa2 shotgun snf suz12 sw1 unlimited	3gamma assisted bmecs bovine coimmunoprecipitation coip colocalization desorption eif1ax fingerprinting flight fret interacted ionization isoform maldi mammary methionine mtor positively promote proved resonance stat5 synthesis tof translation trigger triggered
Tagcloud (Difference) ?		apex1 apurine apyrimidine brg1 coherently depict endonuclease escs h2a impalpha4 importin indefinitely macro nono npm1 npr nucleoplasmin octamer pdcd5 pou renew renewal ribonucleoprotein roa2 shotgun snf suz12 sw1 unlimited	3gamma assisted bmecs bovine coimmunoprecipitation coip colocalization desorption eif1ax fingerprinting flight fret interacted ionization isoform maldi mammary methionine mtor positively promote proved resonance stat5 synthesis tof translation trigger triggered
Tagcloud (Intersection) ?