IPO5 and RANBP2

Number of citations of the paper that reports this interaction (PMID 9114010)
35

Data Source:
HPRD (in vitro, in vivo)

		IPO5	RANBP2
Gene Name		importin 5	RAN binding protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Pore Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Membrane Nuclear Membrane Intracellular Membrane-bounded Organelle	Nuclear Pore Mitochondrion Cytosol Membrane Nuclear Membrane Nuclear Inclusion Body Nuclear Pore Nuclear Basket
	Molecular Function	GTPase Inhibitor Activity Protein Binding Ran GTPase Binding Protein Transporter Activity Poly(A) RNA Binding	RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Zinc Ion Binding Ran GTPase Binding Ligase Activity
	Biological Process	NLS-bearing Protein Import Into Nucleus Ribosomal Protein Import Into Nucleus Viral Process Positive Regulation Of Protein Import Into Nucleus Negative Regulation Of Catalytic Activity Cellular Response To Amino Acid Stimulus	Mitotic Cell Cycle Protein Peptidyl-prolyl Isomerization Carbohydrate Metabolic Process Protein Folding Protein Import Into Nucleus Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Glucose Transport Viral Process Protein Sumoylation Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Negative Regulation Of Glucokinase Activity Small Molecule Metabolic Process MRNA Transport Transmembrane Transport Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis
Pathways		Influenza Viral RNA Transcription and Replication Influenza Infection Influenza Life Cycle vRNP Assembly	Mitotic Prometaphase Separation of Sister Chromatids Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown Mitotic Anaphase SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear Pore Complex (NPC) Disassembly Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Resolution of Sister Chromatid Cohesion Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport Mitotic Metaphase and Anaphase
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: ACD BHLHB9 DPPA3 DTNBP1 H1F0 NUP153 NUP214 NUP62 NUP98 RAG2 RAN RANBP2 RPL13 RPL23 RPL23A RPL5 RPL7 RPS7 SRP19 TERF1 TINF2 WASL	34 interactors: AKAP13 ARID4B CALM1 CDCA8 CUL1 FHOD1 HDAC4 IFT140 IPO5 KPNA1 KPNA2 KPNB1 LRPAP1 MDM2 NUP62 NXF1 OPN1LW OPN1MW PARK2 RAN RANGAP1 SAE1 SENP1 SP100 SUMO1 TAF1 TNPO1 TOP2B TP53 UBA2 UBE2I UBTD1 XPO1 XPOT
Entrez ID		3843	5903
HPRD ID		03597	03111
Ensembl ID		ENSG00000065150	ENSG00000153201
Uniprot IDs		B3KWG6 O00410 Q9BVS9	P49792
PDB IDs			1RRP 1XKE 1Z5S 3UIN 3UIO 3UIP 4GA0 4I9Y 4L6E 4LQW
Enriched GO Terms of Interacting Partners?		Viral Transcription Viral Life Cycle Protein Localization To Organelle Membrane Organization Establishment Of Protein Localization To Organelle Cytoplasmic Transport Viral Process Protein Targeting Intracellular Transport Protein Localization Cellular Localization Establishment Of Localization In Cell Cellular Protein Localization Protein Transport SRP-dependent Cotranslational Protein Targeting To Membrane Establishment Of Protein Localization Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Intracellular Protein Transport Protein Localization To Endoplasmic Reticulum Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Protein Targeting To Membrane Cellular Nitrogen Compound Metabolic Process Mitotic Nuclear Envelope Disassembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nuclear Envelope Disassembly Nitrogen Compound Metabolic Process Establishment Of Protein Localization To Membrane Nuclear Import Nucleocytoplasmic Transport Nuclear Transport Translational Termination Nuclear-transcribed MRNA Catabolic Process Nuclear Envelope Organization Glucose Transport MRNA Catabolic Process Hexose Transport Translational Elongation Negative Regulation Of Telomere Maintenance Via Telomerase RNA Catabolic Process Cellular Protein Complex Disassembly Protein Localization To Membrane Protein Complex Disassembly Regulation Of Glucose Transport Organelle Organization Translational Initiation Negative Regulation Of Telomere Maintenance	Viral Process Nucleocytoplasmic Transport Nuclear Transport Protein Localization To Nucleus Protein Localization To Organelle Cytoplasmic Transport Peptidyl-lysine Modification Protein Import Into Nucleus Nuclear Import Cellular Localization Protein Sumoylation Protein Import NLS-bearing Protein Import Into Nucleus Positive Regulation Of Metabolic Process Cellular Protein Localization Establishment Of Localization In Cell Intracellular Transport Mitotic Cell Cycle Regulation Of Protein Export From Nucleus Intracellular Transport Of Virus Protein Localization Regulation Of Intracellular Transport Regulation Of Nucleocytoplasmic Transport Establishment Of Protein Localization To Organelle Nuclear Export Cellular Response To Organic Substance Regulation Of Protein Localization Regulation Of Protein Catabolic Process Cell Cycle Regulation Of Intracellular Protein Transport Protein Targeting Protein Modification By Small Protein Conjugation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Binding Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Establishment Of Protein Localization SMT3-dependent Protein Catabolic Process Intracellular Protein Transport Positive Regulation Of Cellular Protein Catabolic Process Response To Organic Substance Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Establishment Of Protein Localization Regulation Of Cell Cycle Positive Regulation Of Cellular Metabolic Process Mitotic Cell Cycle Process Positive Regulation Of Proteolysis Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Gene Expression Peptidyl-amino Acid Modification Positive Regulation Of Cellular Biosynthetic Process
Tagcloud ?		apex1 apurine apyrimidine brg1 coherently depict endonuclease escs h2a impalpha4 importin indefinitely macro nono npm1 npr nucleoplasmin octamer pdcd5 pou renew renewal ribonucleoprotein roa2 shotgun snf suz12 sw1 unlimited	adar colorectal contain dcaf12l2 exomes glt1d1 hot instability itga7 map1b microsatellite mrgprx4 oncogenes personalized profiling psrc1 respective rps6kl1 sequenced sncaip spot spots tceal6 tubb6 validated validation vegfb wbp5 zbtb2
Tagcloud (Difference) ?		apex1 apurine apyrimidine brg1 coherently depict endonuclease escs h2a impalpha4 importin indefinitely macro nono npm1 npr nucleoplasmin octamer pdcd5 pou renew renewal ribonucleoprotein roa2 shotgun snf suz12 sw1 unlimited	adar colorectal contain dcaf12l2 exomes glt1d1 hot instability itga7 map1b microsatellite mrgprx4 oncogenes personalized profiling psrc1 respective rps6kl1 sequenced sncaip spot spots tceal6 tubb6 validated validation vegfb wbp5 zbtb2
Tagcloud (Intersection) ?