IPO5 and RPL7

Number of citations of the paper that reports this interaction (PMID 20828572)
3

Data Source:
BioGRID (affinity chromatography technology, pull down)

		IPO5	RPL7
Gene Name		importin 5	ribosomal protein L7
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Pore Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Membrane Nuclear Membrane Intracellular Membrane-bounded Organelle	Nucleus Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Ribonucleoprotein Complex Extracellular Vesicular Exosome
	Molecular Function	GTPase Inhibitor Activity Protein Binding Ran GTPase Binding Protein Transporter Activity Poly(A) RNA Binding	DNA Binding RNA Binding MRNA Binding Structural Constituent Of Ribosome Protein Binding Protein Homodimerization Activity Poly(A) RNA Binding
	Biological Process	NLS-bearing Protein Import Into Nucleus Ribosomal Protein Import Into Nucleus Viral Process Positive Regulation Of Protein Import Into Nucleus Negative Regulation Of Catalytic Activity Cellular Response To Amino Acid Stimulus	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RRNA Processing Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Ribosomal Large Subunit Biogenesis Cellular Protein Metabolic Process
Pathways		Influenza Viral RNA Transcription and Replication Influenza Infection Influenza Life Cycle vRNP Assembly	Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS			Crohn's disease ( 22412388)
Protein-Protein Interactions		22 interactors: ACD BHLHB9 DPPA3 DTNBP1 H1F0 NUP153 NUP214 NUP62 NUP98 RAG2 RAN RANBP2 RPL13 RPL23 RPL23A RPL5 RPL7 RPS7 SRP19 TERF1 TINF2 WASL	9 interactors: IL7R IPO5 NR4A1 PHC2 PPP1CC RAN SGOL1 YWHAQ ZNF7
Entrez ID		3843	6129
HPRD ID		03597	05004
Ensembl ID		ENSG00000065150	ENSG00000147604
Uniprot IDs		B3KWG6 O00410 Q9BVS9	P18124
PDB IDs			3J3B
Enriched GO Terms of Interacting Partners?		Viral Transcription Viral Life Cycle Protein Localization To Organelle Membrane Organization Establishment Of Protein Localization To Organelle Cytoplasmic Transport Viral Process Protein Targeting Intracellular Transport Protein Localization Cellular Localization Establishment Of Localization In Cell Cellular Protein Localization Protein Transport SRP-dependent Cotranslational Protein Targeting To Membrane Establishment Of Protein Localization Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Intracellular Protein Transport Protein Localization To Endoplasmic Reticulum Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Protein Targeting To Membrane Cellular Nitrogen Compound Metabolic Process Mitotic Nuclear Envelope Disassembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nuclear Envelope Disassembly Nitrogen Compound Metabolic Process Establishment Of Protein Localization To Membrane Nuclear Import Nucleocytoplasmic Transport Nuclear Transport Translational Termination Nuclear-transcribed MRNA Catabolic Process Nuclear Envelope Organization Glucose Transport MRNA Catabolic Process Hexose Transport Translational Elongation Negative Regulation Of Telomere Maintenance Via Telomerase RNA Catabolic Process Cellular Protein Complex Disassembly Protein Localization To Membrane Protein Complex Disassembly Regulation Of Glucose Transport Organelle Organization Translational Initiation Negative Regulation Of Telomere Maintenance	Protein Targeting Cell Division Interleukin-7-mediated Signaling Pathway Protein Import Into Nucleus Nuclear Import Cellular Protein Localization Ribosomal Small Subunit Export From Nucleus Protein Import Protein Localization To Nucleus Negative Regulation Of T Cell Mediated Cytotoxicity Centriole-centriole Cohesion Mitotic Cell Cycle Intracellular Receptor Signaling Pathway Ribosomal Large Subunit Export From Nucleus Positive Regulation Of Intracellular Transport Cellular Response To Organic Substance Ribosomal Subunit Export From Nucleus Ribosomal Protein Import Into Nucleus Regulation Of Gene Expression Protein Localization Intracellular Protein Transport Nucleocytoplasmic Transport Nuclear Transport Attachment Of Spindle Microtubules To Kinetochore NLS-bearing Protein Import Into Nucleus
Tagcloud ?		apex1 apurine apyrimidine brg1 coherently depict endonuclease escs h2a impalpha4 importin indefinitely macro nono npm1 npr nucleoplasmin octamer pdcd5 pou renew renewal ribonucleoprotein roa2 shotgun snf suz12 sw1 unlimited
Tagcloud (Difference) ?		apex1 apurine apyrimidine brg1 coherently depict endonuclease escs h2a impalpha4 importin indefinitely macro nono npm1 npr nucleoplasmin octamer pdcd5 pou renew renewal ribonucleoprotein roa2 shotgun snf suz12 sw1 unlimited
Tagcloud (Intersection) ?