IPO5 and RPL23

Number of citations of the paper that reports this interaction (PMID 9114010)
35

Data Source:
HPRD (in vitro)

		IPO5	RPL23
Gene Name		importin 5	ribosomal protein L23
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Pore Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Membrane Nuclear Membrane Intracellular Membrane-bounded Organelle	Nucleolus Cytoplasm Cytosol Ribosome Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome
	Molecular Function	GTPase Inhibitor Activity Protein Binding Ran GTPase Binding Protein Transporter Activity Poly(A) RNA Binding	Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding
	Biological Process	NLS-bearing Protein Import Into Nucleus Ribosomal Protein Import Into Nucleus Viral Process Positive Regulation Of Protein Import Into Nucleus Negative Regulation Of Catalytic Activity Cellular Response To Amino Acid Stimulus	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination Ribosomal Protein Import Into Nucleus SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways		Influenza Viral RNA Transcription and Replication Influenza Infection Influenza Life Cycle vRNP Assembly	Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: ACD BHLHB9 DPPA3 DTNBP1 H1F0 NUP153 NUP214 NUP62 NUP98 RAG2 RAN RANBP2 RPL13 RPL23 RPL23A RPL5 RPL7 RPS7 SRP19 TERF1 TINF2 WASL	8 interactors: APP BCCIP CDC42 CLU DAPP1 EPS8L2 IPO5 RELA
Entrez ID		3843	9349
HPRD ID		03597	04716
Ensembl ID		ENSG00000065150
Uniprot IDs		B3KWG6 O00410 Q9BVS9	P62829
PDB IDs			3J3B
Enriched GO Terms of Interacting Partners?		Viral Transcription Viral Life Cycle Protein Localization To Organelle Membrane Organization Establishment Of Protein Localization To Organelle Cytoplasmic Transport Viral Process Protein Targeting Intracellular Transport Protein Localization Cellular Localization Establishment Of Localization In Cell Cellular Protein Localization Protein Transport SRP-dependent Cotranslational Protein Targeting To Membrane Establishment Of Protein Localization Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Intracellular Protein Transport Protein Localization To Endoplasmic Reticulum Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Protein Targeting To Membrane Cellular Nitrogen Compound Metabolic Process Mitotic Nuclear Envelope Disassembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nuclear Envelope Disassembly Nitrogen Compound Metabolic Process Establishment Of Protein Localization To Membrane Nuclear Import Nucleocytoplasmic Transport Nuclear Transport Translational Termination Nuclear-transcribed MRNA Catabolic Process Nuclear Envelope Organization Glucose Transport MRNA Catabolic Process Hexose Transport Translational Elongation Negative Regulation Of Telomere Maintenance Via Telomerase RNA Catabolic Process Cellular Protein Complex Disassembly Protein Localization To Membrane Protein Complex Disassembly Regulation Of Glucose Transport Organelle Organization Translational Initiation Negative Regulation Of Telomere Maintenance	Regulation Of Catalytic Activity Cellular Response To Stimulus Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Innate Immune Response Positive Regulation Of Cellular Component Biogenesis Response To Stimulus Regulation Of Protein Catabolic Process Positive Regulation Of Neuron Death Platelet Degranulation Regulation Of Protein Phosphorylation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Protein Metabolic Process Blood Coagulation Hemostasis Regulation Of ERBB Signaling Pathway Positive Regulation Of Tau-protein Kinase Activity Regulation Of Neuronal Signal Transduction Microglial Cell Proliferation Acetaldehyde Metabolic Process Posttranscriptional Regulation Of Gene Expression Regulation Of Synapse Structure Or Activity Hair Follicle Development Positive Regulation Of Protein Metabolic Process Hair Cycle Process Immune Response Response To Amino Acid Hair Cycle Regulation Of Phosphorylation Defense Response Synaptic Growth At Neuromuscular Junction Positive Regulation Of Neurofibrillary Tangle Assembly Positive Regulation Of Schwann Cell Differentiation Positive Regulation Of Hair Follicle Cell Proliferation Regulation Of Cell Projection Assembly Regulation Of Body Fluid Levels Positive Regulation Of NF-kappaB Transcription Factor Activity Wound Healing Microtubule-based Transport Negative Regulation Of Protein Complex Assembly Regulation Of Phosphorus Metabolic Process Regulation Of Signal Transduction Regulation Of Protein Stability Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Catalytic Activity Positive Regulation Of Immune Response Submandibular Salivary Gland Formation Collateral Sprouting In Absence Of Injury Actin Filament Branching
Tagcloud ?		apex1 apurine apyrimidine brg1 coherently depict endonuclease escs h2a impalpha4 importin indefinitely macro nono npm1 npr nucleoplasmin octamer pdcd5 pou renew renewal ribonucleoprotein roa2 shotgun snf suz12 sw1 unlimited	apocytochrome infa l20 l22 l33 liverwort marchantia peta petb petd preprotein psbb psbe psbf psbh rpl14 rpl16 rpl20 rpl22 rpl33 rpoa rps11 rps12 rps18 rps3 rps8 secx ugg
Tagcloud (Difference) ?		apex1 apurine apyrimidine brg1 coherently depict endonuclease escs h2a impalpha4 importin indefinitely macro nono npm1 npr nucleoplasmin octamer pdcd5 pou renew renewal ribonucleoprotein roa2 shotgun snf suz12 sw1 unlimited	apocytochrome infa l20 l22 l33 liverwort marchantia peta petb petd preprotein psbb psbe psbf psbh rpl14 rpl16 rpl20 rpl22 rpl33 rpoa rps11 rps12 rps18 rps3 rps8 secx ugg
Tagcloud (Intersection) ?