KIF5C

Description		kinesin family member 5C
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Kinesin Complex Microtubule Dendrite Dendrite Cytoplasm Ciliary Rootlet Cell Projection Neuron Projection Neuronal Cell Body Axonal Growth Cone GABA-ergic Synapse Postsynaptic Cytosol Distal Axon Axon Cytoplasm
	Molecular Function	Nucleotide Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding Plus-end-directed Microtubule Motor Activity Hydrolase Activity ATP Hydrolysis Activity Apolipoprotein Receptor Binding
	Biological Process	Organelle Organization Microtubule-based Movement Axon Guidance Motor Neuron Axon Guidance Intracellular MRNA Localization Synaptic Vesicle Transport MRNA Transport Anterograde Dendritic Transport Of Messenger Ribonucleoprotein Complex Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex Anterograde Axonal Protein Transport
Pathways		Insulin processing
Drugs
Diseases
GWAS		Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Chronotype ( 30696823) Mild age-related type 2 diabetes ( 34737425)
Interacting Genes		10 interacting genes: CSNK2A1 ITSN1 KIF5A KLC1 KLC3 MEOX2 NCOA2 PCNT SNAPIN YWHAG
Entrez ID		3800
HPRD ID		18371
Ensembl ID		ENSG00000168280
Uniprot IDs		O60282 Q59GB8
PDB IDs
Enriched GO Terms of Interacting Partners?		Kinesin Binding Kinesin Complex Ciliary Rootlet Axo-dendritic Transport Microtubule Microtubule-based Movement Microtubule-based Process Retrograde Axonal Transport Transport Along Microtubule Cytoskeleton-dependent Intracellular Transport Synaptic Vesicle Transport Microtubule-based Transport Negative Regulation Of Translational Initiation Intracellular Transport Vesicle Transport Along Microtubule Anterograde Axonal Transport Cytoskeletal Motor Activity Establishment Of Protein Localization Vesicle Cytoskeletal Trafficking Axon Cytoplasm Positive Regulation Of Late Endosome To Lysosome Transport Axonal Transport Neuron Projection Cellular Localization Establishment Of Localization In Cell Organelle Transport Along Microtubule Clathrin-dependent Synaptic Vesicle Endocytosis Protein Localization To Vacuole Vesicle-mediated Transport In Synapse Regulation Of Translational Initiation Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Establishment Of Vesicle Localization Protein Kinase C Inhibitor Activity Cellular Response To Thyroglobulin Triiodothyronine Intracellular Protein Localization Cytoplasm Vesicle Localization Positive Regulation Of Caveolin-mediated Endocytosis Protein Transport Positive Regulation Of Aggrephagy Retrograde Neuronal Dense Core Vesicle Transport Somite Specification Positive Regulation Of Intracellular Transport Response To Thyroglobulin Triiodothyronine Terminal Button Organization Sperm Mitochondrial Sheath Assembly Protein-containing Complex Disassembly Intracellular Protein Transport Vacuolar Transport
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