ISCU and IKZF1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ISCU	IKZF1
Gene Name		iron-sulfur cluster assembly enzyme	IKAROS family zinc finger 1 (Ikaros)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol	Nucleus Pericentric Heterochromatin Cytoplasm Protein Complex
	Molecular Function	Iron Ion Binding Protein Binding Protein Complex Scaffold Iron-sulfur Cluster Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Nitrogen Fixation Iron-sulfur Cluster Assembly Small Molecule Metabolic Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Natural Killer Cell Differentiation Transcription, DNA-templated Cell Cycle Mesoderm Development Chromatin Modification B Cell Differentiation T Cell Differentiation Forebrain Development Positive Regulation Of Multicellular Organism Growth Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Lymph Node Development Thymus Development Peyer's Patch Development Positive Regulation Of NK T Cell Differentiation Retina Development In Camera-type Eye
Pathways
Drugs
Diseases
GWAS			Acute lymphoblastic leukemia (childhood) ( 23512250 19684603 19684604) Crohn's disease ( 21102463) Hippocampal atrophy ( 19668339) IgG glycosylation ( 23382691) Inflammatory bowel disease ( 23128233) Mean corpuscular volume ( 19862010) Red blood cell traits ( 23222517) Systemic lupus erythematosus ( 23273568 19838193)
Protein-Protein Interactions		12 interactors: AGTRAP BANP CCDC172 FAM9B GOLGA2 HPRT1 IKZF1 KRT40 LNX1 MID2 NECAB2 NUP62	75 interactors: AEN ALKBH3 ANKRD11 AP1M1 AP2M1 ARMC7 BYSL C19orf66 C1orf109 C1orf174 C8orf33 CBX8 CDK2AP2 CEP57L1 CHD3 CKS1B CSNK1G1 CTBP1 CTBP2 DCX DDX6 DYRK2 FAM161A FAM214B FAM50B FAM74A4 FGF12 FRMD6 GLRX3 GMCL1P1 GTF2B HDAC1 HDAC2 IKZF2 IKZF3 IKZF4 IKZF5 ISCU KIF9 LMO3 LSM4 MAD2L2 MCRS1 MORF4L1 MORF4L2 MTA1 NEK6 NOC4L NUDT21 PIN1 PNKP PRKAB2 PSMA1 PSMA4 RAD51D RBBP8 RWDD2B SAP18 SCNM1 SDCBP SH2D4A SIN3A SIN3B SMARCA4 SNRPF SNW1 SPATC1L SYT17 TBP TDG UBE2I WTAP ZMAT2 ZNF417 ZNF581
Entrez ID		23479	10320
HPRD ID		14828	04318
Ensembl ID		ENSG00000136003	ENSG00000185811
Uniprot IDs		B3KQ30 B4DNC9 Q9H1K1	Q13422
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Neutrophil Differentiation GMP Salvage GMP Catabolic Process Guanine Salvage Cell Cycle Adenine Salvage Hypoxanthine Salvage Positive Regulation Of Dopamine Metabolic Process Hypoxanthine Metabolic Process Hypoxanthine Biosynthetic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling GMP Biosynthetic Process Purine Nucleoside Monophosphate Catabolic Process Purine Ribonucleoside Salvage Positive Regulation Of NK T Cell Differentiation Angiotensin-activated Signaling Pathway Protein Localization To Microtubule Regulation Of I-kappaB Kinase/NF-kappaB Signaling GMP Metabolic Process Positive Regulation Of Granulocyte Differentiation Protein Homooligomerization Purine Ribonucleoside Catabolic Process IMP Salvage Purine Nucleobase Biosynthetic Process Negative Regulation Of Viral Release From Host Cell Purine Nucleotide Salvage Striatum Development Negative Regulation Of Viral Entry Into Host Cell Lymph Node Development Peyer's Patch Development Regulation Of Dopamine Metabolic Process Grooming Behavior Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway IMP Biosynthetic Process Regulation Of Viral Entry Into Host Cell Natural Killer Cell Differentiation Negative Regulation Of Viral Transcription Protein Localization To Cytoskeleton Regulation Of Viral Release From Host Cell Lymphocyte Activation IMP Metabolic Process Subpallium Development Positive Regulation Of ERBB Signaling Pathway Purine Ribonucleotide Catabolic Process Cytolysis Purine-containing Compound Salvage Protein Oligomerization	RNA Metabolic Process Gene Expression Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Chromatin Organization Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression, Epigenetic Cellular Response To Stress Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Organelle Organization Chromosome Organization Chromatin Modification Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression, Epigenetic Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Viral Process Negative Regulation Of Gene Expression Histone Deacetylation Protein Deacetylation Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Histone Modification Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter DNA Repair Regulation Of Cell Cycle Signal Transduction By P53 Class Mediator Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway DNA Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Metabolic Process Regulation Of Cell Cycle Phase Transition RNA Splicing
Tagcloud ?			agree china cnki cochrane databases deletion derive efs eligible embase estimation ethnicity hazard infrastructure intervals lymphoblastic meta methodology precise pubmed random ratios science stratified subgroups unfavorable updated wanfang web
Tagcloud (Difference) ?			agree china cnki cochrane databases deletion derive efs eligible embase estimation ethnicity hazard infrastructure intervals lymphoblastic meta methodology precise pubmed random ratios science stratified subgroups unfavorable updated wanfang web
Tagcloud (Intersection) ?