ISCU and AGTRAP

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ISCU	AGTRAP
Gene Name		iron-sulfur cluster assembly enzyme	angiotensin II receptor-associated protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol	Golgi Membrane Nucleoplasm Cytoplasm Endoplasmic Reticulum Membrane Plasma Membrane Cell Cortex Integral Component Of Membrane Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Iron Ion Binding Protein Binding Protein Complex Scaffold Iron-sulfur Cluster Binding	Angiotensin Type II Receptor Activity Protein Binding
	Biological Process	Nitrogen Fixation Iron-sulfur Cluster Assembly Small Molecule Metabolic Process	Response To Hypoxia Regulation Of Blood Pressure Angiotensin-activated Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Systolic blood pressure ( 19430483)
Protein-Protein Interactions		12 interactors: AGTRAP BANP CCDC172 FAM9B GOLGA2 HPRT1 IKZF1 KRT40 LNX1 MID2 NECAB2 NUP62	70 interactors: ACSF2 ADCK3 AGTR1 AGTR2 ALDH18A1 AP3M1 ARAF ARFIP2 BPIFA2 C12orf10 CAPNS1 CD160 CPLX1 CRCT1 DDA1 DDX55 DGCR6 FAM114A1 FAM160A2 FAM64A FARS2 FASTKD3 FATE1 GABARAPL2 GAD1 GAD2 GDNF GNB2L1 GTF3C1 HARS2 HIST1H4G HMGB1 HSCB HSPA4 ISCU KIAA0368 LMO2 LNX1 MCEE MIEF1 MIEF2 MRM1 MTERF3 MUTYH NDRG4 NFU1 NFYB NKG7 PBX3 PCTP PDHX PITPNC1 PTPN9 RMDN2 SENP2 SNX1 SPG21 SSX3 SSX5 STAG3L1 SUCLA2 SYT16 TBRG4 TCEANC2 TFAM TPD52L3 TUBA1B TXN2 ZFYVE21 ZNF391
Entrez ID		23479	57085
HPRD ID		14828	16379
Ensembl ID		ENSG00000136003	ENSG00000177674
Uniprot IDs		B3KQ30 B4DNC9 Q9H1K1	Q6RW13
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Neutrophil Differentiation GMP Salvage GMP Catabolic Process Guanine Salvage Cell Cycle Adenine Salvage Hypoxanthine Salvage Positive Regulation Of Dopamine Metabolic Process Hypoxanthine Metabolic Process Hypoxanthine Biosynthetic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling GMP Biosynthetic Process Purine Nucleoside Monophosphate Catabolic Process Purine Ribonucleoside Salvage Positive Regulation Of NK T Cell Differentiation Angiotensin-activated Signaling Pathway Protein Localization To Microtubule Regulation Of I-kappaB Kinase/NF-kappaB Signaling GMP Metabolic Process Positive Regulation Of Granulocyte Differentiation Protein Homooligomerization Purine Ribonucleoside Catabolic Process IMP Salvage Purine Nucleobase Biosynthetic Process Negative Regulation Of Viral Release From Host Cell Purine Nucleotide Salvage Striatum Development Negative Regulation Of Viral Entry Into Host Cell Lymph Node Development Peyer's Patch Development Regulation Of Dopamine Metabolic Process Grooming Behavior Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway IMP Biosynthetic Process Regulation Of Viral Entry Into Host Cell Natural Killer Cell Differentiation Negative Regulation Of Viral Transcription Protein Localization To Cytoskeleton Regulation Of Viral Release From Host Cell Lymphocyte Activation IMP Metabolic Process Subpallium Development Positive Regulation Of ERBB Signaling Pathway Purine Ribonucleotide Catabolic Process Cytolysis Purine-containing Compound Salvage Protein Oligomerization	Succinate Metabolic Process Glutamate Decarboxylation To Succinate Glutamate Metabolic Process Iron-sulfur Cluster Assembly Renin-angiotensin Regulation Of Aldosterone Production Regulation Of Blood Vessel Size By Renin-angiotensin Dicarboxylic Acid Metabolic Process Glutamate Catabolic Process Angiotensin-activated Signaling Pathway Positive Regulation Of Oxidoreductase Activity Positive Regulation Of Protein Homooligomerization Positive Regulation Of Mitochondrial Fission Small Molecule Metabolic Process Negative Regulation Of Phagocytosis Regulation Of Mitochondrial Fission Regulation Of Blood Volume By Renin-angiotensin Dicarboxylic Acid Catabolic Process Neurotransmitter Biosynthetic Process Carboxylic Acid Metabolic Process Regulation Of Oxidoreductase Activity Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Positive Regulation Of Protein Oligomerization Regulation Of Renal Sodium Excretion Regulation Of Branching Involved In Ureteric Bud Morphogenesis Carboxylic Acid Catabolic Process Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Organic Acid Metabolic Process Positive Regulation Of Monooxygenase Activity Regulation Of Excretion Exploration Behavior Regulation Of Protein Oligomerization Neurotransmitter Metabolic Process Neurotransmitter Secretion Mitochondrion Organization Ornithine Biosynthetic Process Negative Regulation Of Apoptotic Cell Clearance Succinyl-CoA Pathway Posterior Compartment Specification Anterior Compartment Pattern Formation Aldosterone Secretion Nitrogen Fixation Vasodilation By Angiotensin Involved In Regulation Of Systemic Arterial Blood Pressure L-methylmalonyl-CoA Metabolic Process Phospholipase C-activating Angiotensin-activated Signaling Pathway Positive Regulation Of Embryonic Development Positive Regulation Of Protein Targeting To Membrane Metanephros Morphogenesis Cellular Amino Acid Catabolic Process Cardiac Muscle Tissue Growth Biosynthetic Process
Tagcloud ?			adrenal alpha1 apelin apln covers ephx2 epoxide genesis gja1 glands hydrolase hypertensive isolating kynu kynureninase kyoto normotensive osteonectin prone rgs2 rising shr shrsp sparc spock2 substrains urotensin uts2 wky
Tagcloud (Difference) ?			adrenal alpha1 apelin apln covers ephx2 epoxide genesis gja1 glands hydrolase hypertensive isolating kynu kynureninase kyoto normotensive osteonectin prone rgs2 rising shr shrsp sparc spock2 substrains urotensin uts2 wky
Tagcloud (Intersection) ?