GRIP1 and EFNB1

Number of citations of the paper that reports this interaction (PMID 10197531)
57

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		GRIP1	EFNB1
Gene Name		glutamate receptor interacting protein 1	ephrin-B1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Cytosol Plasma Membrane Cytoplasmic Membrane-bounded Vesicle Cell Junction Dendrite Neuron Projection Membrane Raft Postsynaptic Membrane Recycling Endosome	Nucleus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Membrane Raft Synapse Extracellular Vesicular Exosome
	Molecular Function	Transcription Coactivator Activity Protein Binding Beta-catenin Binding Protein C-terminus Binding Receptor Signaling Complex Scaffold Activity Glucocorticoid Receptor Binding Androgen Receptor Binding	Protein Binding Ephrin Receptor Binding
	Biological Process	Synaptic Transmission Protein Localization Dendrite Development Androgen Receptor Signaling Pathway Intracellular Signal Transduction Positive Regulation Of Transcription, DNA-templated	Neural Crest Cell Migration Cell Adhesion Cell-cell Signaling Axon Guidance Embryonic Pattern Specification Positive Regulation Of T Cell Proliferation Ephrin Receptor Signaling Pathway
Pathways		Trafficking of GluR2-containing AMPA receptors Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity Trafficking of AMPA receptors Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Transmission across Chemical Synapses	EPHB-mediated forward signaling Ephrin signaling EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		34 interactors: AR CARM1 CSPG4 EFNA5 EFNB1 EFNB2 EP300 ESR1 FLII GPR37 GRIA1 GRIA2 GRIA3 GRIA4 GRIK1 GRIK2 GRIK3 GRIPAP1 GRM3 HIST1H3A IRF3 NCOA6 NR2F1 NR3C1 NUMBL PICK1 PPARG PRKD2 PRMT1 RXRA RXRB THRA UBE2I VDR	16 interactors: CAPN10 CUL3 EPHA3 EPHB1 EPHB2 GRIP1 MYC NCK2 PICK1 PTPN13 RGS3 SDCBP SORBS1 SRC TIAM1 YWHAQ
Entrez ID		23426	1947
HPRD ID		19086	02072
Ensembl ID		ENSG00000155974	ENSG00000090776
Uniprot IDs		Q9Y3R0	P98172
PDB IDs		2JIL
Enriched GO Terms of Interacting Partners?		Intracellular Receptor Signaling Pathway Signal Transduction Glutamate Receptor Signaling Pathway Signaling Cell Communication Steroid Hormone Mediated Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Hormone-mediated Signaling Pathway Synaptic Transmission, Glutamatergic Cellular Response To Stimulus DNA-templated Transcription, Initiation Cellular Response To Steroid Hormone Stimulus Neuron-neuron Synaptic Transmission Response To Stimulus Cell Surface Receptor Signaling Pathway Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Response To Steroid Hormone Response To Organic Cyclic Compound Cell-cell Signaling Regulation Of Cellular Process Regulation Of Signaling Positive Regulation Of Transcription From RNA Polymerase II Promoter System Development Response To Lipid Multicellular Organismal Development Transcription From RNA Polymerase II Promoter Negative Regulation Of Synaptic Transmission Regulation Of Nitrogen Compound Metabolic Process Response To Hormone Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Hormone Stimulus Response To Organic Substance Cellular Response To Organic Substance Synaptic Transmission Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Anatomical Structure Development Developmental Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Negative Regulation Of Synaptic Transmission, Glutamatergic Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Biosynthetic Process RNA Biosynthetic Process	Ephrin Receptor Signaling Pathway Regulation Of Signaling Regulation Of Cellular Component Organization Enzyme Linked Receptor Protein Signaling Pathway Neuron Development Axon Guidance Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Morphogenesis Involved In Differentiation Regulation Of Signal Transduction Neuron Differentiation Cell Projection Organization Neuron Projection Development Axonogenesis Cell Development Axon Development Regulation Of Organelle Organization Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Stress Fiber Assembly Cell Morphogenesis Generation Of Neurons Dendritic Spine Organization Neurogenesis Nervous System Development Regulation Of Intracellular Signal Transduction Cell Surface Receptor Signaling Pathway Locomotion Cell Migration Cell Projection Morphogenesis Cell Part Morphogenesis Signal Transduction Cell Motility Cellular Response To Stimulus Positive Regulation Of Cellular Component Biogenesis Apoptotic Process Actin Cytoskeleton Organization Movement Of Cell Or Subcellular Component Signaling Programmed Cell Death Actin Filament-based Process Cell Communication Cell Death Death Multicellular Organismal Development Anatomical Structure Development Positive Regulation Of Organelle Organization Positive Regulation Of Transport Anatomical Structure Morphogenesis Optic Nerve Morphogenesis
Tagcloud ?		acids androgen associate auxiliary beta1 box cip coactivator coactivators efficient equivalent glucocorticoid hormone includes lacks lxxll motifs mutational nid nidaux nr nrs p160 progesterone recruit retinoid separable src	allow attenuation cetuximab contribution dimerization disappointing drives egf egfr ephrinb1 erbb1 head hnscc mechanistically mediate neck overexpress partner partners persistent persists rearrangements shift slowed squamous substantial targeted trigger yielded
Tagcloud (Difference) ?		acids androgen associate auxiliary beta1 box cip coactivator coactivators efficient equivalent glucocorticoid hormone includes lacks lxxll motifs mutational nid nidaux nr nrs p160 progesterone recruit retinoid separable src	allow attenuation cetuximab contribution dimerization disappointing drives egf egfr ephrinb1 erbb1 head hnscc mechanistically mediate neck overexpress partner partners persistent persists rearrangements shift slowed squamous substantial targeted trigger yielded
Tagcloud (Intersection) ?