GRIP1 and EEPD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GRIP1	EEPD1
Description		glutamate receptor interacting protein 1	endonuclease/exonuclease/phosphatase family domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Endomembrane System Postsynaptic Density Membrane Dendrite Cytoplasmic Vesicle Cell Projection Neuron Projection Perikaryon Synapse Postsynaptic Membrane	Plasma Membrane
	Molecular Function	Protein Binding Beta-catenin Binding Signaling Receptor Complex Adaptor Activity	DNA Binding Catalytic Activity Protein Binding
	Biological Process	Intracellular Signal Transduction Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Positive Regulation Of Neuron Projection Arborization	DNA Repair Positive Regulation Of Cholesterol Efflux
Pathways		Trafficking of GluR2-containing AMPA receptors	NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs
Diseases
GWAS		Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252) Post bronchodilator FEV1/FVC ratio ( 26634245)	Apolipoprotein A1 levels ( 32203549) Fibrinogen levels ( 26561523 28107422) HDL cholesterol levels ( 32203549) High light scatter reticulocyte count ( 32888494) LDL cholesterol levels ( 32203549) Mean spheric corpuscular volume ( 32888494) Obesity-related traits ( 23251661) Platelet count ( 21507922) Pulse pressure ( 30224653) Refractive error ( 32231278) Reticulocyte count ( 32888494) Schizophrenia ( 30285260)
Interacting Genes		46 interacting genes: AGAP2 AR BAG4 CARM1 CSPG4 DEPDC1B DZIP3 EEPD1 EFNA5 EFNB1 EFNB2 EP300 ESR1 FGF12 FLII FXR1 FXR2 GPR37 GRIA1 GRIA3 GRIA4 GRIK1 GRIK2 GRIPAP1 GRM2 GRM3 GRM7 H3C1 HUS1 IRF3 KMT5B MFAP3 NCOA6 NEK6 NR3C1 NUMBL PICK1 PPARG PRKD2 PRMT1 RXRA THRA UBE2I VDR WDR6 XDH	3 interacting genes: APP CRYAA GRIP1
Entrez ID		23426	80820
HPRD ID		19086	13884
Ensembl ID		ENSG00000155974	ENSG00000122547
Uniprot IDs		A0A8V8TLS6 Q9Y3R0	Q7L9B9
PDB IDs		2JIL
Enriched GO Terms of Interacting Partners?		Glutamate Receptor Signaling Pathway Regulation Of Cell Communication Glutamate-gated Receptor Activity Nuclear Receptor Activity Presynaptic Membrane Regulation Of Signaling Positive Regulation Of Cell Communication Positive Regulation Of Signaling Synaptic Transmission, Glutamatergic Modulation Of Chemical Synaptic Transmission Glutamate-gated Calcium Ion Channel Activity Positive Regulation Of Signal Transduction Chemical Synaptic Transmission Nuclear Receptor-mediated Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Trans-synaptic Signaling Positive Regulation Of Intracellular Signal Transduction Synaptic Signaling Ligand-gated Monoatomic Ion Channel Activity Regulation Of Biological Quality Glutamate Receptor Activity Regulation Of Synaptic Transmission, Glutamatergic Cell-cell Signaling Cell Surface Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Intracellular Signal Transduction Signaling Transmitter-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential Synapse Ligand-gated Monoatomic Ion Channel Activity Involved In Regulation Of Presynaptic Membrane Potential Ligand-gated Ion Channel Signaling Pathway Transcription Coregulator Binding Cell Communication Hormone-mediated Signaling Pathway Intracellular Receptor Signaling Pathway Postsynaptic Membrane Signal Transduction Nuclear Steroid Receptor Activity Postsynaptic Density Membrane AMPA Glutamate Receptor Activity Retinoic Acid Receptor Signaling Pathway MRNA Transcription Regulation Of Presynaptic Membrane Potential Regulation Of Synaptic Plasticity Adenylate Cyclase-inhibiting G Protein-coupled Glutamate Receptor Signaling Pathway Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Glutamatergic Synapse Regulation Of Signal Transduction Estrogen Response Element Binding	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Perikaryon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission Response To Light Stimulus NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Neuron Projection Axon Choice Point Recognition Lens Fiber Cell Morphogenesis Heparan Sulfate Binding Signaling Receptor Activator Activity Positive Regulation Of Neuron Projection Arborization Peptidase Activator Activity Cellular Response To Manganese Ion Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Regulation Of Cellular Component Organization Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Regulation Of Growth Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?