GRIP1 and CARM1

Number of citations of the paper that reports this interaction (PMID 17882261)
25

Data Source:
BioGRID (pull down)

		GRIP1	CARM1
Gene Name		glutamate receptor interacting protein 1	coactivator-associated arginine methyltransferase 1
Image
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Cytosol Plasma Membrane Cytoplasmic Membrane-bounded Vesicle Cell Junction Dendrite Neuron Projection Membrane Raft Postsynaptic Membrane Recycling Endosome	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Transcription Coactivator Activity Protein Binding Beta-catenin Binding Protein C-terminus Binding Receptor Signaling Complex Scaffold Activity Glucocorticoid Receptor Binding Androgen Receptor Binding	Transcription Coactivator Activity Protein Binding Beta-catenin Binding Protein Methyltransferase Activity Histone-arginine N-methyltransferase Activity Protein-arginine N-methyltransferase Activity Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone Methyltransferase Activity (H3-R17 Specific) Histone Methyltransferase Activity Protein Homodimerization Activity Transcription Regulatory Region DNA Binding Lysine-acetylated Histone Binding
	Biological Process	Synaptic Transmission Protein Localization Dendrite Development Androgen Receptor Signaling Pathway Intracellular Signal Transduction Positive Regulation Of Transcription, DNA-templated	Regulation Of Growth Plate Cartilage Chondrocyte Proliferation Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Positive Regulation Of Cell Proliferation Pathogenesis Viral Process Histone Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Protein Binding Regulation Of Intracellular Estrogen Receptor Signaling Pathway Histone H3-R2 Methylation Histone H3-R17 Methylation Cellular Lipid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Fat Cell Differentiation Response To CAMP Endochondral Bone Morphogenesis
Pathways		Trafficking of GluR2-containing AMPA receptors Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity Trafficking of AMPA receptors Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Transmission across Chemical Synapses	PPARA activates gene expression Organelle biogenesis and maintenance Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Chromatin organization REV-ERBA represses gene expression RORA activates circadian gene expression Mitochondrial biogenesis RMTs methylate histone arginines Regulation of cholesterol biosynthesis by SREBP (SREBF) Chromatin modifying enzymes Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation YAP1- and WWTR1 (TAZ)-stimulated gene expression Activation of gene expression by SREBF (SREBP) Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) Transcriptional activation of mitochondrial biogenesis BMAL1:CLOCK,NPAS2 activates circadian gene expression Orphan transporters
Drugs
Diseases
GWAS
Protein-Protein Interactions		34 interactors: AR CARM1 CSPG4 EFNA5 EFNB1 EFNB2 EP300 ESR1 FLII GPR37 GRIA1 GRIA2 GRIA3 GRIA4 GRIK1 GRIK2 GRIK3 GRIPAP1 GRM3 HIST1H3A IRF3 NCOA6 NR2F1 NR3C1 NUMBL PICK1 PPARG PRKD2 PRMT1 RXRA RXRB THRA UBE2I VDR	33 interactors: AXIN1 CREBBP CTNNB1 DAXX DNAJA3 ELAVL1 EP300 FLII FOS GRIP1 H3F3A H3F3B HIST1H3A MALT1 MEF2D MYOD1 MYOG NCOA1 NCOA2 NUDT21 PABPC1 PABPN1 PIAS1 PYGO1 QKI RABGAP1 RELA SMARCA4 SPAG8 SRC SRCAP TP53 UBE2I
Entrez ID		23426	10498
HPRD ID		19086	09158
Ensembl ID		ENSG00000155974	ENSG00000142453
Uniprot IDs		Q9Y3R0	Q86X55
PDB IDs		2JIL	2Y1W 2Y1X 4IKP
Enriched GO Terms of Interacting Partners?		Intracellular Receptor Signaling Pathway Signal Transduction Glutamate Receptor Signaling Pathway Signaling Cell Communication Steroid Hormone Mediated Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Hormone-mediated Signaling Pathway Synaptic Transmission, Glutamatergic Cellular Response To Stimulus DNA-templated Transcription, Initiation Cellular Response To Steroid Hormone Stimulus Neuron-neuron Synaptic Transmission Response To Stimulus Cell Surface Receptor Signaling Pathway Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Response To Steroid Hormone Response To Organic Cyclic Compound Cell-cell Signaling Regulation Of Cellular Process Regulation Of Signaling Positive Regulation Of Transcription From RNA Polymerase II Promoter System Development Response To Lipid Multicellular Organismal Development Transcription From RNA Polymerase II Promoter Negative Regulation Of Synaptic Transmission Regulation Of Nitrogen Compound Metabolic Process Response To Hormone Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Hormone Stimulus Response To Organic Substance Cellular Response To Organic Substance Synaptic Transmission Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Anatomical Structure Development Developmental Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Negative Regulation Of Synaptic Transmission, Glutamatergic Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Biosynthetic Process RNA Biosynthetic Process	Regulation Of Gene Expression Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Peptidyl-lysine Modification Chromatin Organization Transcription, DNA-templated Histone Acetylation RNA Biosynthetic Process Nitrogen Compound Metabolic Process Internal Peptidyl-lysine Acetylation Intracellular Receptor Signaling Pathway Peptidyl-lysine Acetylation Negative Regulation Of Cellular Metabolic Process Internal Protein Amino Acid Acetylation RNA Metabolic Process Protein Acetylation Intracellular Steroid Hormone Receptor Signaling Pathway Organelle Organization Androgen Receptor Signaling Pathway Cellular Macromolecule Biosynthetic Process DNA Methylation On Cytosine Negative Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Regulation Of Cellular Process Chromosome Organization Transcription From RNA Polymerase II Promoter Muscle Structure Development DNA Methylation
Tagcloud ?		acids androgen associate auxiliary beta1 box cip coactivator coactivators efficient equivalent glucocorticoid hormone includes lacks lxxll motifs mutational nid nidaux nr nrs p160 progesterone recruit retinoid separable src	additionally arginine biological blocked candidates cardiovascular cofactor compound cyanine docking effectively guide methyltransferase micromolar occupying optimization pentamethine permeated prmt1 prmt5 prmt8 probes provided roadmap selectivity serve systematically transduction trimethine
Tagcloud (Difference) ?		acids androgen associate auxiliary beta1 box cip coactivator coactivators efficient equivalent glucocorticoid hormone includes lacks lxxll motifs mutational nid nidaux nr nrs p160 progesterone recruit retinoid separable src	additionally arginine biological blocked candidates cardiovascular cofactor compound cyanine docking effectively guide methyltransferase micromolar occupying optimization pentamethine permeated prmt1 prmt5 prmt8 probes provided roadmap selectivity serve systematically transduction trimethine
Tagcloud (Intersection) ?