Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
PIH1D2 and EIF4A2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
PIH1D2
EIF4A2
Gene Name
PIH1 domain containing 2
eukaryotic translation initiation factor 4A2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Eukaryotic Translation Initiation Factor 4F Complex
Perinuclear Region Of Cytoplasm
Molecular Function
Ral GTPase Binding
Translation Initiation Factor Activity
Helicase Activity
Protein Binding
ATP Binding
ATPase Activity
Poly(A) RNA Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Nuclear-transcribed MRNA Poly(A) Tail Shortening
Translation
Translational Initiation
Regulation Of Translational Initiation
Gene Expression
Viral Process
Cytokine-mediated Signaling Pathway
Cellular Protein Metabolic Process
Negative Regulation Of RNA-directed RNA Polymerase Activity
Pathways
Translation initiation complex formation
Translation
Deadenylation of mRNA
ISG15 antiviral mechanism
Interferon Signaling
Cytokine Signaling in Immune system
L13a-mediated translational silencing of Ceruloplasmin expression
Antiviral mechanism by IFN-stimulated genes
Deadenylation-dependent mRNA decay
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Initiation
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
Cap-dependent Translation Initiation
Drugs
Diseases
GWAS
Protein-Protein Interactions
11 interactors:
DPH3
EIF4A2
GFAP
IGF2BP3
ITGB3BP
KRTAP12-4
MDFI
MRFAP1L1
MVP
RALA
REL
17 interactors:
BRCA1
CLNS1A
DPPA4
ECT2
EIF4G1
EIF4G2
IPO11
MDFI
NEK2
PDCD4
PFDN1
PIH1D2
SLC16A9
SSX2IP
TK1
TRIM36
TRIM39
Entrez ID
120379
1974
HPRD ID
14021
03062
Ensembl ID
ENSG00000150773
ENSG00000156976
Uniprot IDs
E9PD82
Q8WWB5
Q14240
Q9NZE6
PDB IDs
3BOR
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of RNA-directed RNA Polymerase Activity
Positive Regulation Of Schwann Cell Proliferation
Negative Regulation Of Cellular Metabolic Process
Regulation Of Protein Metabolic Process
Regulation Of Cytokine Biosynthetic Process
MRNA Transport
Negative Regulation Of Biosynthetic Process
RNA Transport
RNA Localization
Membrane Raft Localization
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Negative Regulation Of Protein Transport
Regulation Of Cellular Process
Bergmann Glial Cell Differentiation
Cellular Response To Stimulus
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Binding
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Interleukin-12 Biosynthetic Process
Negative Regulation Of Protein Autophosphorylation
Regulation Of Translation
Signal Transduction
Positive Regulation Of Glial Cell Proliferation
Regulation Of Neurotransmitter Uptake
Peptidyl-diphthamide Biosynthetic Process From Peptidyl-histidine
Negative Regulation Of Transferase Activity
Regulation Of Cellular Localization
Intermediate Filament Organization
Regulation Of Interleukin-12 Biosynthetic Process
Negative Regulation Of Protein Tyrosine Kinase Activity
Trophoblast Giant Cell Differentiation
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Signaling
Astrocyte Development
Cell Communication
Cytoplasmic Sequestering Of Transcription Factor
Dorsal/ventral Axis Specification
Regulation Of Cell Cycle
Centrosome Organization
Microtubule Organizing Center Organization
Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Regulation Of Microtubule Cytoskeleton Organization
Regulation Of Cellular Protein Metabolic Process
Regulation Of Microtubule-based Process
Regulation Of Protein Metabolic Process
Negative Regulation Of DNA Binding
Cell Death
Death
Regulation Of Centrosome Cycle
Centrosome Cycle
Positive Regulation Of Histone H4-K20 Methylation
Negative Regulation Of Centriole-centriole Cohesion
Positive Regulation Of Histone H4-K16 Acetylation
Fetal Process Involved In Parturition
Regulation Of Translational Initiation
Regulation Of JUN Kinase Activity
Skeletal Muscle Cell Proliferation
Positive Regulation Of Histone H3-K9 Acetylation
Regulation Of Chromosome Segregation
Cell Cycle
Regulation Of DNA Binding
Embryo Development Ending In Birth Or Egg Hatching
Negative Regulation Of Binding
Positive Regulation Of Histone H4 Acetylation
Negative Regulation Of Histone H3-K4 Methylation
Regulation Of Centriole-centriole Cohesion
Microtubule Cytoskeleton Organization
Negative Regulation Of Cell Cycle
Apoptotic Process
Cellular Response To Indole-3-methanol
Regulation Of Mitotic Centrosome Separation
Programmed Cell Death
Regulation Of Cell Cycle Process
Developmental Process
Ribosomal Protein Import Into Nucleus
Intraciliary Transport Involved In Cilium Morphogenesis
Negative Regulation Of Centriole Replication
Response To Cortisol
Thymidine Metabolic Process
Cell Cycle Process
Regulation Of Cytoskeleton Organization
Response To Ionizing Radiation
Dosage Compensation By Inactivation Of X Chromosome
Deoxyribonucleoside Monophosphate Biosynthetic Process
Protein K6-linked Ubiquitination
Regulation Of JNK Cascade
Negative Regulation Of Cytoskeleton Organization
Tagcloud
?
4f
adult
biogenesis
confer
deprivation
differed
differs
eif4f
eif4g1
fetal
gestation
helicase
hepatocyte
insensitive
liver
nutrient
oligopyrimidine
preinitiation
rapamycin
refeeding
ribosome
sensing
top
tracts
translation
weights
went
Tagcloud (Difference)
?
4f
adult
biogenesis
confer
deprivation
differed
differs
eif4f
eif4g1
fetal
gestation
helicase
hepatocyte
insensitive
liver
nutrient
oligopyrimidine
preinitiation
rapamycin
refeeding
ribosome
sensing
top
tracts
translation
weights
went
Tagcloud (Intersection)
?