PIH1D2 and DPH3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PIH1D2	DPH3
Gene Name		PIH1 domain containing 2	diphthamide biosynthesis 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Ral GTPase Binding	Protein Binding Metal Ion Binding
	Biological Process		Peptidyl-diphthamide Biosynthetic Process From Peptidyl-histidine Post-translational Protein Modification Cellular Protein Metabolic Process Negative Regulation Of Protein Secretion Positive Regulation Of Binding
Pathways			Synthesis of diphthamide-EEF2 Post-translational protein modification Gamma carboxylation, hypusine formation and arylsulfatase activation
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: DPH3 EIF4A2 GFAP IGF2BP3 ITGB3BP KRTAP12-4 MDFI MRFAP1L1 MVP RALA REL	4 interactors: ADIPOR1 PIH1D2 RPL8 SERGEF
Entrez ID		120379	285381
HPRD ID		14021	16412
Ensembl ID		ENSG00000150773
Uniprot IDs		E9PD82 Q8WWB5	Q96FX2
PDB IDs			2JR7
Enriched GO Terms of Interacting Partners?		Negative Regulation Of RNA-directed RNA Polymerase Activity Positive Regulation Of Schwann Cell Proliferation Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Cytokine Biosynthetic Process MRNA Transport Negative Regulation Of Biosynthetic Process RNA Transport RNA Localization Membrane Raft Localization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Protein Transport Regulation Of Cellular Process Bergmann Glial Cell Differentiation Cellular Response To Stimulus Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Binding Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Interleukin-12 Biosynthetic Process Negative Regulation Of Protein Autophosphorylation Regulation Of Translation Signal Transduction Positive Regulation Of Glial Cell Proliferation Regulation Of Neurotransmitter Uptake Peptidyl-diphthamide Biosynthetic Process From Peptidyl-histidine Negative Regulation Of Transferase Activity Regulation Of Cellular Localization Intermediate Filament Organization Regulation Of Interleukin-12 Biosynthetic Process Negative Regulation Of Protein Tyrosine Kinase Activity Trophoblast Giant Cell Differentiation Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Signaling Astrocyte Development Cell Communication Cytoplasmic Sequestering Of Transcription Factor Dorsal/ventral Axis Specification	Leptin-mediated Signaling Pathway Adiponectin-activated Signaling Pathway Positive Regulation Of Ran GTPase Activity Cellular Response To Leptin Stimulus Response To Leptin
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