COL4A3BP and COL4A3

Number of citations of the paper that reports this interaction (PMID 10212244)
14

Data Source:
HPRD (in vitro)

		COL4A3BP	COL4A3
Gene Name		collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	collagen, type IV, alpha 3 (Goodpasture antigen)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Mitochondrion Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm	Extracellular Region Collagen Type IV Trimer Basement Membrane Endoplasmic Reticulum Lumen
	Molecular Function	Protein Kinase Activity Protein Binding Ceramide Transporter Activity Phosphatidylinositol-4-phosphate Binding Ceramide Binding	Integrin Binding Structural Molecule Activity Extracellular Matrix Structural Constituent Protein Binding Metalloendopeptidase Inhibitor Activity
	Biological Process	Cell Morphogenesis In Utero Embryonic Development Heart Morphogenesis Protein Phosphorylation Sphingolipid Metabolic Process Ceramide Metabolic Process Muscle Contraction Immune Response Endoplasmic Reticulum Organization Signal Transduction Cell Proliferation Sphingolipid Biosynthetic Process Response To Endoplasmic Reticulum Stress ER To Golgi Ceramide Transport Small Molecule Metabolic Process Lipid Homeostasis Mitochondrion Morphogenesis	Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cell Adhesion Cell Surface Receptor Signaling Pathway Axon Guidance Sensory Perception Of Sound Blood Circulation Cell Proliferation Negative Regulation Of Cell Proliferation Negative Regulation Of Endopeptidase Activity Negative Regulation Of Angiogenesis Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process Glomerular Basement Membrane Development Endothelial Cell Apoptotic Process
Pathways			Signaling by PDGF NCAM1 interactions Collagen formation Axon guidance Collagen degradation Anchoring fibril formation Non-integrin membrane-ECM interactions Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures Laminin interactions ECM proteoglycans Integrin cell surface interactions Collagen biosynthesis and modifying enzymes NCAM signaling for neurite out-growth
Drugs
Diseases
GWAS		Quantitative traits ( 19197348)	Corneal structure ( 23291589) Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000)
Protein-Protein Interactions		10 interactors: ACTL8 ARL6IP1 CBS COL4A3 CSNK1G2 ITGB3BP POM121 RTN3 RTN4 TGM2	17 interactors: ANTXR2 APP CAMK2B CD93 COL4A3BP DCN FBLN2 FN1 HABP2 MATN2 MFAP2 MMP9 OSM SAA1 SERPINE2 TGFBI USH2A
Entrez ID		10087	1285
HPRD ID		05246	00354
Ensembl ID		ENSG00000113163	ENSG00000169031
Uniprot IDs		Q9Y5P4	Q01955
PDB IDs		2E3M 2E3N 2E3O 2E3P 2E3Q 2E3R 2E3S 2RSG 2Z9Y 2Z9Z 3H3Q 3H3R 3H3S 3H3T
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Organization Cysteine Biosynthetic Process From Serine Homocysteine Catabolic Process Cysteine Biosynthetic Process Via Cystathionine Apoptotic Process Programmed Cell Death Cell Death Death Endomembrane System Organization Cell Surface Receptor Signaling Pathway Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Transsulfuration Endothelial Cell Apoptotic Process Regulation Of Branching Morphogenesis Of A Nerve Cysteine Biosynthetic Process L-cysteine Catabolic Process Hydrogen Sulfide Biosynthetic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death L-serine Catabolic Process Positive Regulation Of Cell Death Hydrogen Sulfide Metabolic Process Regulation Of Apoptotic Process Salivary Gland Cavitation Regulation Of Cell Death Cysteine Metabolic Process Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Mitochondrial Calcium Ion Concentration Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Neurotrophin Signaling Pathway Homocysteine Metabolic Process	Extracellular Matrix Organization Extracellular Structure Organization System Development Immune System Process Response To Wounding Multicellular Organismal Development Anatomical Structure Development Anatomical Structure Morphogenesis Extracellular Matrix Disassembly Developmental Process Wound Healing Generation Of Neurons Cell Morphogenesis Nervous System Development Neurogenesis Cell Activation Cell Morphogenesis Involved In Differentiation Blood Coagulation Cell Differentiation Reproductive Process Hemostasis Response To Stress Platelet Activation Endodermal Cell Differentiation Acute-phase Response Regulation Of Meiosis Peptide Cross-linking Organ Development Leukocyte Migration Mating Regulation Of Body Fluid Levels Regulation Of Meiotic Cell Cycle Chemotaxis Endoderm Formation Response To Abiotic Stimulus Regulation Of Growth Seminal Vesicle Epithelium Development Dendrite Regeneration Inhibitory G-protein Coupled Receptor Phosphorylation Regulation Of Cell Adhesion Tissue Development Neurological System Process Response To External Stimulus Cell Adhesion Platelet Degranulation Regulation Of Neurogenesis Acute Inflammatory Response Locomotion Neuromuscular Process Controlling Balance Synaptic Growth At Neuromuscular Junction
Tagcloud ?			alport amplified aras ascending audiological audiometric august autosomal certainly curves descending drop eighty exons fibroblast flat groove hearing impairment inheritance moderate oae recessive sensorineural sequenced sixteen wherein xlas
Tagcloud (Difference) ?			alport amplified aras ascending audiological audiometric august autosomal certainly curves descending drop eighty exons fibroblast flat groove hearing impairment inheritance moderate oae recessive sensorineural sequenced sixteen wherein xlas
Tagcloud (Intersection) ?