COL4A3BP and ITGB3BP

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		COL4A3BP	ITGB3BP
Gene Name		collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	integrin beta 3 binding protein (beta3-endonexin)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Mitochondrion Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm	Condensed Chromosome Kinetochore Nucleus Nucleoplasm Cytoplasm Cytosol Membrane
	Molecular Function	Protein Kinase Activity Protein Binding Ceramide Transporter Activity Phosphatidylinositol-4-phosphate Binding Ceramide Binding	Signal Transducer Activity Protein C-terminus Binding
	Biological Process	Cell Morphogenesis In Utero Embryonic Development Heart Morphogenesis Protein Phosphorylation Sphingolipid Metabolic Process Ceramide Metabolic Process Muscle Contraction Immune Response Endoplasmic Reticulum Organization Signal Transduction Cell Proliferation Sphingolipid Biosynthetic Process Response To Endoplasmic Reticulum Stress ER To Golgi Ceramide Transport Small Molecule Metabolic Process Lipid Homeostasis Mitochondrion Morphogenesis	Mitotic Cell Cycle Nucleosome Assembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Mitotic Nuclear Division Cell Adhesion Signal Transduction CENP-A Containing Nucleosome Assembly Positive Regulation Of Apoptotic Process Neurotrophin TRK Receptor Signaling Pathway Cell Division Apoptotic Signaling Pathway
Pathways			Mitotic Prometaphase Signalling by NGF Chromosome Maintenance Cell death signalling via NRAGE, NRIF and NADE Separation of Sister Chromatids Deposition of new CENPA-containing nucleosomes at the centromere p75 NTR receptor-mediated signalling Mitotic Anaphase M Phase Cell Cycle, Mitotic Nucleosome assembly NRIF signals cell death from the nucleus Resolution of Sister Chromatid Cohesion Mitotic Metaphase and Anaphase
Drugs
Diseases
GWAS		Quantitative traits ( 19197348)
Protein-Protein Interactions		10 interactors: ACTL8 ARL6IP1 CBS COL4A3 CSNK1G2 ITGB3BP POM121 RTN3 RTN4 TGM2	21 interactors: ACTN2 APP ARFIP2 CCNA2 COL4A3BP DDX24 ESR1 ITGB3 ITGB5 KDM1A KIFC3 MAPK6 MTA1 NFKB1 PIH1D2 RECQL5 RXRA RXRG SVIL THRA UBR7
Entrez ID		10087	23421
HPRD ID		05246	09267
Ensembl ID		ENSG00000113163	ENSG00000142856
Uniprot IDs		Q9Y5P4	Q13352
PDB IDs		2E3M 2E3N 2E3O 2E3P 2E3Q 2E3R 2E3S 2RSG 2Z9Y 2Z9Z 3H3Q 3H3R 3H3S 3H3T
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Organization Cysteine Biosynthetic Process From Serine Homocysteine Catabolic Process Cysteine Biosynthetic Process Via Cystathionine Apoptotic Process Programmed Cell Death Cell Death Death Endomembrane System Organization Cell Surface Receptor Signaling Pathway Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Transsulfuration Endothelial Cell Apoptotic Process Regulation Of Branching Morphogenesis Of A Nerve Cysteine Biosynthetic Process L-cysteine Catabolic Process Hydrogen Sulfide Biosynthetic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death L-serine Catabolic Process Positive Regulation Of Cell Death Hydrogen Sulfide Metabolic Process Regulation Of Apoptotic Process Salivary Gland Cavitation Regulation Of Cell Death Cysteine Metabolic Process Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Mitochondrial Calcium Ion Concentration Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Neurotrophin Signaling Pathway Homocysteine Metabolic Process	Intracellular Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Response To Lipid Hormone-mediated Signaling Pathway Positive Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Positive Regulation Of Cellular Metabolic Process Signaling Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Organic Cyclic Compound Positive Regulation Of Gene Expression Cell Communication Cellular Response To Lipid Regulation Of Branching Involved In Prostate Gland Morphogenesis Positive Regulation Of Cellular Biosynthetic Process Protein Homotetramerization Platelet Degranulation DNA-templated Transcription, Initiation Response To Steroid Hormone Response To Stimulus Signal Transduction Response To Organic Cyclic Compound Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Organelle Organization Response To Hormone Cellular Response To Hormone Stimulus Protein Tetramerization Cellular Response To Stimulus Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Response To Stress Negative Regulation Of Lipid Transport Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Retinoic Acid Receptor Signaling Pathway Negative Regulation Of Transport Regulation Of RNA Metabolic Process Mating Behavior Tissue Development Organ Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Blood Coagulation Cell-matrix Adhesion Hemostasis
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