KIAA0368 and UIMC1

Number of citations of the paper that reports this interaction (PMID 20682791)
15

Data Source:
BioGRID (two hybrid)

		KIAA0368	UIMC1
Gene Name		KIAA0368	ubiquitin interaction motif containing 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Proteasome Complex Nucleus Early Endosome Late Endosome Multivesicular Body Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Trans-Golgi Network Centrosome Membrane Cytoplasmic Membrane-bounded Vesicle ER To Golgi Transport Vesicle Endocytic Vesicle	Nucleus BRCA1-A Complex
	Molecular Function	Molecular_function	Protein Binding Histone Binding Retinoid X Receptor Binding K63-linked Polyubiquitin Binding
	Biological Process	ER-associated Ubiquitin-dependent Protein Catabolic Process	Double-strand Break Repair Transcription, DNA-templated Response To Ionizing Radiation G2 DNA Damage Checkpoint Positive Regulation Of DNA Repair Negative Regulation Of Transcription, DNA-templated Histone H2A K63-linked Deubiquitination
Pathways
Drugs
Diseases
GWAS			Activated partial thromboplastin time ( 22703881) Menarche and menopause (age at onset) ( 19448621) Menopause (age at onset) ( 22267201)
Protein-Protein Interactions		28 interactors: AGTRAP ANK2 ANKRD17 CCDC57 CEP170B CKS1B CMTM5 CPD DNAJB9 DST FBXO2 GAREML GOLGB1 HNRNPM MKI67 MYH10 PCM1 PCYT1B RAB11FIP4 RNF168 SF3B2 SPECC1L SYNE1 UBE2G2 UBE2Q1 UIMC1 VPS11 ZNF483	14 interactors: ATP8A2 BABAM1 BRCC3 CEP57 ESR1 FAM175A FANCG HIST2H2AC INO80B KIAA0368 MDC1 NR6A1 SKIL TP53
Entrez ID		23392	51720
HPRD ID		11078	11482
Ensembl ID		ENSG00000136813	ENSG00000087206
Uniprot IDs		J3KN16 Q5VYK3	Q96RL1
PDB IDs			2RR9
Enriched GO Terms of Interacting Partners?		ER-associated Ubiquitin-dependent Protein Catabolic Process Nucleus Localization Cell Cycle Establishment Of Nucleus Localization Cell Cycle Process Positive Regulation Of DNA Repair Cell Division Endomembrane System Organization Negative Regulation Of Muscle Cell Differentiation Histone H2A-K13 Ubiquitination Protein Localization To T-tubule Histone H2A-K15 Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of DNA Repair Histone H2A K63-linked Ubiquitination T-tubule Organization Protein Localization To M-band Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Response To DNA Damage Stimulus Proteolysis Involved In Cellular Protein Catabolic Process Proteasomal Protein Catabolic Process	Cell Cycle Checkpoint Double-strand Break Repair DNA Repair DNA Damage Checkpoint Cell Cycle Process Positive Regulation Of Response To DNA Damage Stimulus Response To Radiation Cellular Response To DNA Damage Stimulus Cell Cycle Positive Regulation Of DNA Repair Regulation Of Response To DNA Damage Stimulus DNA Metabolic Process G2 DNA Damage Checkpoint Response To Ionizing Radiation Chromatin Organization Regulation Of DNA Repair Cellular Response To Stress Organelle Organization Chromosome Organization Chromatin Modification Response To Abiotic Stimulus Nucleobase-containing Compound Metabolic Process Protein K63-linked Deubiquitination Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Multicellular Organismal Reproductive Process Positive Regulation Of DNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Multicellular Organism Reproduction Protein Import Into Nucleus, Translocation Cellular Response To Stimulus Response To Stimulus Transcription Initiation From RNA Polymerase II Promoter Response To X-ray Spermatogenesis Male Gamete Generation Nitrogen Compound Metabolic Process Reproduction DNA-templated Transcription, Initiation Single Organism Reproductive Process Gamete Generation Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Response To Antibiotic Reproductive Process Rhythmic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Ovarian Follicle Development Sexual Reproduction Negative Regulation Of Macromitophagy Oligodendrocyte Apoptotic Process
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