ECPAS and GAREM2

Number of citations of the paper that reports this interaction (PubMedID 20682791)
103

Data Source:
BioGRID (two hybrid)

		ECPAS	GAREM2
Description		Ecm29 proteasome adaptor and scaffold	GRB2 associated regulator of MAPK1 subtype 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Proteasome Complex Nucleus Nucleoplasm Cytoplasm Endosome Early Endosome Late Endosome Multivesicular Body Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Trans-Golgi Network Centrosome Cytoskeleton Membrane COPII-coated ER To Golgi Transport Vesicle Endocytic Vesicle Cytoplasmic Vesicle
	Molecular Function	Protein Binding Molecular Adaptor Activity Proteasome Binding
	Biological Process	ERAD Pathway Proteasome Assembly	Response To Stress Social Behavior Cognition Neuron Projection Extension
Pathways
Drugs
Diseases
GWAS
Interacting Genes		36 interacting genes: AGTRAP ANK2 ANKRD17 BSND CCDC57 CEBPA CEP170B CKS1B CMTM5 CMTM6 CPD DGAT2L6 DNAJB9 DST FBXO2 GAREM2 GOLGB1 HNRNPM HSD17B13 HSPB1 MAL2 MKI67 MYH10 PCM1 PCYT1B RAB11FIP4 RNF168 SF3B2 SPECC1L SYNE1 TNFRSF10D UBE2G2 UBE2Q1 UIMC1 VPS11 ZNF483	3 interacting genes: ECPAS ITSN1 ITSN2
Entrez ID		23392	150946
HPRD ID		11078
Ensembl ID		ENSG00000136813	ENSG00000157833
Uniprot IDs		A0AAA9X0G7 Q5VYK3	Q75VX8
PDB IDs
Enriched GO Terms of Interacting Partners?			Clathrin-dependent Synaptic Vesicle Endocytosis Intracellular Vesicle Clathrin-dependent Endocytosis Synaptic Vesicle Endocytosis Presynaptic Endocytosis Vesicle-mediated Transport In Synapse Presynaptic Membrane Receptor-mediated Endocytosis Molecular Adaptor Activity Protein-macromolecule Adaptor Activity Guanyl-nucleotide Exchange Factor Activity Positive Regulation Of Caveolin-mediated Endocytosis Endosomal Transport Regulation Of Caveolin-mediated Endocytosis Regulation Of Modification Of Postsynaptic Actin Cytoskeleton Postsynaptic Endocytic Zone Positive Regulation Of Growth Hormone Secretion Postsynaptic Actin Cytoskeleton Endocytosis Regulation Of Growth Hormone Secretion Proteasome Assembly Regulation Of Modification Of Postsynaptic Structure Apical Dendrite Proline-rich Region Binding Proteasome Binding Regulation Of Modification Of Synaptic Structure Calcium Ion Binding Positive Regulation Of Dendrite Extension Import Into Cell Centrosome Endosome COPII-coated ER To Golgi Transport Vesicle Positive Regulation Of Dendritic Spine Development Cytoplasmic Vesicle Multivesicular Body Regulation Of Dendritic Spine Development Proteasome Complex Clathrin-coated Pit Endocytic Vesicle
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