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ECPAS and SYNE1
Number of citations of the paper that reports this interaction (PubMedID
20682791
)
103
Data Source:
BioGRID
(two hybrid)
ECPAS
SYNE1
Description
Ecm29 proteasome adaptor and scaffold
spectrin repeat containing nuclear envelope protein 1
Image
No pdb structure
GO Annotations
Cellular Component
Proteasome Complex
Nucleus
Nucleoplasm
Cytoplasm
Endosome
Early Endosome
Late Endosome
Multivesicular Body
Endoplasmic Reticulum
Endoplasmic Reticulum-Golgi Intermediate Compartment
Trans-Golgi Network
Centrosome
Cytoskeleton
Membrane
COPII-coated ER To Golgi Transport Vesicle
Endocytic Vesicle
Cytoplasmic Vesicle
P-body
Nucleus
Nuclear Envelope
Nuclear Outer Membrane
Nucleoplasm
Nucleolus
Cytoplasm
Golgi Apparatus
Cytoskeleton
Membrane
Sarcomere
Nuclear Membrane
Meiotic Nuclear Membrane Microtubule Tethering Complex
Postsynaptic Membrane
Molecular Function
Protein Binding
Molecular Adaptor Activity
Proteasome Binding
RNA Binding
Actin Binding
Protein Binding
Lamin Binding
Enzyme Binding
Identical Protein Binding
Protein Homodimerization Activity
Actin Filament Binding
Cytoskeleton-nuclear Membrane Anchor Activity
Biological Process
ERAD Pathway
Proteasome Assembly
Nucleus Organization
Golgi Organization
Spermatogenesis
Cell Differentiation
Muscle Cell Differentiation
Nuclear Matrix Anchoring At Nuclear Membrane
Pathways
Meiotic synapsis
Drugs
Diseases
Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
Emery-Dreifuss muscular dystrophy
GWAS
Appendicular lean mass (
33097823
)
Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) (
23453885
)
Bipolar disorder (
20351715
21738484
21926972
34002096
28072414
28115744
31043756
)
Bipolar disorder or major depressive disorder (
20351715
)
Bipolar I disorder (
31043756
)
Body mass index (
26426971
)
Endometriosis (
28537267
)
Femur bone mineral density x serum urate levels interaction (
34046847
)
Heel bone mineral density (
30598549
28869591
)
Hip circumference adjusted for BMI (
34021172
)
Post bronchodilator FEV1 (
26634245
)
Tonometry (
17903302
)
Uterine fibroids (
30194396
31249589
31649266
)
Interacting Genes
36 interacting genes:
AGTRAP
ANK2
ANKRD17
BSND
CCDC57
CEBPA
CEP170B
CKS1B
CMTM5
CMTM6
CPD
DGAT2L6
DNAJB9
DST
FBXO2
GAREM2
GOLGB1
HNRNPM
HSD17B13
HSPB1
MAL2
MKI67
MYH10
PCM1
PCYT1B
RAB11FIP4
RNF168
SF3B2
SPECC1L
SYNE1
TNFRSF10D
UBE2G2
UBE2Q1
UIMC1
VPS11
ZNF483
28 interacting genes:
ACTC1
APC
BDKRB2
BTG3
CAPN1
CDC42
CDC5L
CEP63
DISC1
DSCAM
DSCR9
DTNBP1
ECPAS
EMD
ITSN1
LINC00839
LMNA
MTDH
MUSK
MYOM1
NDEL1
PCNT
SH3BP5
TNIK
TP53RK
USP21
USP7
XIAP
Entrez ID
23392
23345
HPRD ID
11078
09762
Ensembl ID
ENSG00000136813
ENSG00000131018
Uniprot IDs
A0AAA9X0G7
Q5VYK3
A0A0C4DG40
B4E3R1
B7Z9Y6
F8WAI0
Q8NF91
PDB IDs
4DXR
6R15
6XF2
Enriched GO Terms of Interacting Partners
?
Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent
Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib
Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I
Antigen Processing And Presentation Of Endogenous Antigen
Natural Killer Cell Lectin-like Receptor Binding
Positive Regulation Of T Cell Mediated Cytotoxicity
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Regulation Of T Cell Mediated Cytotoxicity
Signal Transduction
Antigen Processing And Presentation Of Peptide Antigen
Positive Regulation Of Leukocyte Mediated Cytotoxicity
Regulation Of Postsynapse Organization
Positive Regulation Of Cell Killing
Positive Regulation Of T Cell Mediated Immunity
Cytoskeleton Organization
Regulation Of Synapse Organization
Microtubule Organizing Center
Molecular Adaptor Activity
Regulation Of Leukocyte Mediated Cytotoxicity
Radial Glia-guided Pyramidal Neuron Migration
Antigen Processing And Presentation
Centrosome
Regulation Of T Cell Mediated Immunity
Intracellular Signal Transduction
Natural Killer Cell Mediated Cytotoxicity
Negative Regulation Of Cell Cycle
Natural Killer Cell Mediated Immunity
Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly
Positive Regulation Of Cell Projection Organization
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains
Leading Edge Membrane
Positive Regulation Of Lymphocyte Mediated Immunity
Glutamatergic Synapse
Regulation Of Dendritic Spine Development
Positive Regulation Of Adaptive Immune Response
Negative Regulation Of Cyclin-dependent Protein Kinase Activity
Cytoskeleton
Neuron Projection Morphogenesis
Cytosol
Wnt Signaling Pathway
Positive Regulation Of Pseudopodium Assembly
Cell Projection Morphogenesis
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Leukocyte Mediated Cytotoxicity
Regulation Of Cell Projection Organization
Positive Regulation Of Cellular Component Organization
Regulation Of Wnt Signaling Pathway
Cerebral Cortex Radially Oriented Cell Migration
Regulation Of Protein Localization
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Tagcloud (Difference)
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Tagcloud (Intersection)
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