ECPAS and PCYT1B

Number of citations of the paper that reports this interaction (PubMedID 20682791)
103

Data Source:
BioGRID (two hybrid)

		ECPAS	PCYT1B
Description		Ecm29 proteasome adaptor and scaffold	phosphate cytidylyltransferase 1B, choline
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Proteasome Complex Nucleus Nucleoplasm Cytoplasm Endosome Early Endosome Late Endosome Multivesicular Body Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Trans-Golgi Network Centrosome Cytoskeleton Membrane COPII-coated ER To Golgi Transport Vesicle Endocytic Vesicle Cytoplasmic Vesicle	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Molecular Adaptor Activity Proteasome Binding	Catalytic Activity Choline-phosphate Cytidylyltransferase Activity Protein Binding Transferase Activity Nucleotidyltransferase Activity Phosphatidylcholine Binding Identical Protein Binding
	Biological Process	ERAD Pathway Proteasome Assembly	Ovarian Follicle Development Lipid Metabolic Process Phosphatidylcholine Biosynthetic Process CDP-choline Pathway Spermatogenesis Phospholipid Biosynthetic Process Phosphatidylcholine Metabolic Process Organophosphate Biosynthetic Process
Pathways			Synthesis of PC
Drugs			Choline Choline salicylate
Diseases
GWAS
Interacting Genes		36 interacting genes: AGTRAP ANK2 ANKRD17 BSND CCDC57 CEBPA CEP170B CKS1B CMTM5 CMTM6 CPD DGAT2L6 DNAJB9 DST FBXO2 GAREM2 GOLGB1 HNRNPM HSD17B13 HSPB1 MAL2 MKI67 MYH10 PCM1 PCYT1B RAB11FIP4 RNF168 SF3B2 SPECC1L SYNE1 TNFRSF10D UBE2G2 UBE2Q1 UIMC1 VPS11 ZNF483	7 interacting genes: ACTA1 ACTA2 APP ECPAS PAXIP1 PCYT1A TMEM43
Entrez ID		23392	9468
HPRD ID		11078	05376
Ensembl ID		ENSG00000136813	ENSG00000102230
Uniprot IDs		A0AAA9X0G7 Q5VYK3	Q9Y5K3
PDB IDs
Enriched GO Terms of Interacting Partners?			Cell Body Mesenchyme Migration Positive Regulation Of Hepatic Stellate Cell Contraction Positive Regulation Of Cell Activation Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Filopodium Positive Regulation Of Gene Expression Stress Fiber Juxtaglomerular Apparatus Development Positive Regulation Of Hepatic Stellate Cell Migration Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Choline-phosphate Cytidylyltransferase Activity Chorion Development Glomerular Mesangial Cell Development Mesangial Cell Development Positive Regulation Of Hepatic Stellate Cell Activation Smooth Muscle Contractile Fiber Regulation Of Cell Activation Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Cell Activation Involved In Immune Response Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Endoplasmic Reticulum Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Lamellipodium Skeletal Muscle Thin Filament Assembly Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway
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