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ARFGEF2
Gene Name
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
Image
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Trans-Golgi Network
Microtubule Organizing Center
Cytosol
Axonemal Microtubule
Membrane
Cytoplasmic Membrane-bounded Vesicle
Cell Junction
Cytoplasmic Vesicle
Asymmetric Synapse
Symmetric Synapse
Dendritic Spine
Perinuclear Region Of Cytoplasm
Recycling Endosome
Molecular Function
Guanyl-nucleotide Exchange Factor Activity
ARF Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Myosin Binding
Protein Kinase A Regulatory Subunit Binding
GABA Receptor Binding
Biological Process
Receptor Recycling
Exocytosis
Golgi To Plasma Membrane Transport
Endosome Organization
Endomembrane System Organization
Protein Transport
Vesicle-mediated Transport
Regulation Of ARF Protein Signal Transduction
Positive Regulation Of Tumor Necrosis Factor Production
Intracellular Signal Transduction
Positive Regulation Of GTPase Activity
Pathways
Protein folding
Chaperonin-mediated protein folding
Association of TriC/CCT with target proteins during biosynthesis
Drugs
Diseases
GWAS
Protein-protein Interactions
9 interactors:
ARFGEF1
EXOC7
GABRB1
GABRB2
GABRB3
PNPLA2
PRKAR1A
PRKAR2A
PRPF40A
Entrez ID
10564
HPRD ID
09250
Ensembl ID
ENSG00000124198
Uniprot IDs
Q59FR3
Q86TH5
Q9Y6D5
PDB IDs
3L8N
3SWV
Enriched GO Terms of Interacting Partners
?
Cellular Response To Histamine
Response To Histamine
Cellular Response To Ammonium Ion
Cellular Response To Organonitrogen Compound
Negative Regulation Of CAMP-dependent Protein Kinase Activity
Response To Ammonium Ion
Response To Organonitrogen Compound
Chloride Transmembrane Transport
Regulation Of CAMP-dependent Protein Kinase Activity
Activation Of Protein Kinase A Activity
Chloride Transport
Renal Water Homeostasis
Innervation
Cellular Response To Glucagon Stimulus
Inner Ear Receptor Cell Development
Inorganic Anion Transport
Water Transport
Fluid Transport
Cochlea Development
Activation Of Phospholipase C Activity
Multicellular Organismal Water Homeostasis
Response To Glucagon
Positive Regulation Of Phospholipase C Activity
Transmembrane Transport
Inner Ear Receptor Cell Differentiation
Water Homeostasis
Mechanoreceptor Differentiation
Cellular Response To Organic Substance
Cellular Response To Organic Cyclic Compound
Positive Regulation Of Phospholipase Activity
Anion Transmembrane Transport
Positive Regulation Of Protein Glycosylation In Golgi
Transport
Regulation Of Phospholipase Activity
Positive Regulation Of Lipase Activity
Nerve Development
Renal System Process
Synaptic Transmission
Negative Regulation Of Protein Serine/threonine Kinase Activity
Response To Organic Substance
Energy Reserve Metabolic Process
Positive Regulation Of Protein Glycosylation
Sensory Perception Of Sound
Anion Transport
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
Acylglycerol Acyl-chain Remodeling
Negative Regulation Of Neuron Apoptotic Process
Sensory Perception Of Mechanical Stimulus
Tagcloud
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13q33
15q26
20q13
22q11
already
c20orf199
candidate
chromosomes
copy
cse1l
ddx27
deficiency
duplications
gh
hemizygous
homozygous
individuals
integrin
investigations
itgbl1
kcnb1
mb
oligonucleotide
predispose
ptgis
remaining
snord12
unreported
znfx1