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GNA14
Gene Name
guanine nucleotide binding protein (G protein), alpha 14
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Heterotrimeric G-protein Complex
Plasma Membrane
Extracellular Vesicular Exosome
Molecular Function
G-protein Coupled Receptor Binding
GTPase Activity
Signal Transducer Activity
GTP Binding
G-protein Beta/gamma-subunit Complex Binding
Metal Ion Binding
Biological Process
Signal Transduction
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
Blood Coagulation
Platelet Activation
Phospholipase C-activating Dopamine Receptor Signaling Pathway
Pathways
G alpha (q) signalling events
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
Signaling by GPCR
ADP signalling through P2Y purinoceptor 1
Integration of energy metabolism
Regulation of insulin secretion
Signal amplification
Thrombin signalling through proteinase activated receptors (PARs)
G alpha (q) signalling events
GPCR downstream signaling
Acetylcholine regulates insulin secretion
Gastrin-CREB signalling pathway via PKC and MAPK
Thromboxane signalling through TP receptor
Platelet activation, signaling and aggregation
Free fatty acids regulate insulin secretion
Drugs
Diseases
GWAS
Protein-protein Interactions
9 interactors:
ADRB2
CCR1
CHRM2
CXCR1
CXCR2
DNAL4
JMJD6
OPRL1
SSTR2
Entrez ID
9630
HPRD ID
05095
Ensembl ID
ENSG00000156049
Uniprot IDs
B1ALW3
O95837
PDB IDs
Enriched GO Terms of Interacting Partners
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G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Cell Surface Receptor Signaling Pathway
Dendritic Cell Chemotaxis
G-protein Coupled Receptor Signaling Pathway
Dendritic Cell Migration
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
Interleukin-8-mediated Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Cytosolic Calcium Ion Homeostasis
Chemokine-mediated Signaling Pathway
Signal Transduction
Signaling
Homeostatic Process
Cellular Calcium Ion Homeostasis
Cell Communication
Calcium Ion Homeostasis
Leukocyte Chemotaxis
Cellular Metal Ion Homeostasis
Cellular Response To Stimulus
Cellular Cation Homeostasis
Response To External Stimulus
Cellular Ion Homeostasis
Metal Ion Homeostasis
Cell Chemotaxis
Cellular Chemical Homeostasis
Ion Homeostasis
Endocytosis
Leukocyte Migration
Response To Stimulus
Cellular Homeostasis
Vesicle-mediated Transport
Receptor Internalization
Chemical Homeostasis
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Cell-cell Signaling
Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway
Receptor-mediated Endocytosis
Positive Regulation Of Leukocyte Chemotaxis
Cellular Response To Organic Substance
Regulation Of Bone Mineralization
Negative Regulation Of Neutrophil Apoptotic Process
Histone H3-R2 Demethylation
Histone H4-R3 Demethylation
Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine
Receptor Metabolic Process
Inflammatory Response
Positive Regulation Of Leukocyte Migration
Cytokine-mediated Signaling Pathway
Neuropeptide Signaling Pathway
Positive Regulation Of Chemotaxis
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