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FAF2 and FAF1
Number of citations of the paper that reports this interaction (PMID
12372427
)
6
Data Source:
HPRD
(in vitro)
FAF2
FAF1
Gene Name
Fas associated factor family member 2
Fas (TNFRSF6) associated factor 1
Image
Gene Ontology Annotations
Cellular Component
Endoplasmic Reticulum
Lipid Particle
Cdc48p-Npl4p-Ufd1p AAA ATPase Complex
Intracellular Membrane-bounded Organelle
Nucleus
Nuclear Envelope
Cytosol
CD95 Death-inducing Signaling Complex
Cdc48p-Npl4p-Ufd1p AAA ATPase Complex
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
Ubiquitin Protein Ligase Binding
Lipase Binding
Ubiquitin Binding
Lipase Inhibitor Activity
Protein Binding
Protein Kinase Regulator Activity
Protein Kinase Binding
Protein Domain Specific Binding
Heat Shock Protein Binding
Ubiquitin Protein Ligase Binding
Ubiquitin Binding
NF-kappaB Binding
Biological Process
Response To Unfolded Protein
Lipid Particle Organization
Negative Regulation Of Catalytic Activity
Apoptotic Process
Cytoplasmic Sequestering Of NF-kappaB
Cell Death
Regulation Of Cell Adhesion
Positive Regulation Of Protein Complex Assembly
Regulation Of Protein Catabolic Process
Positive Regulation Of Apoptotic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Kinase Activity
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways
Drugs
Diseases
GWAS
Depression and alcohol dependence (
22064162
)
Ventricular conduction (
21076409
)
Protein-Protein Interactions
7 interactors:
FAF1
FAS
NF1
PNPLA2
PSMD2
UBE2D1
UBQLN2
37 interactors:
ANXA1
ANXA7
ASCC2
CASP8
CD40
CDC73
CDKN1A
CSNK2A1
CSNK2B
DNAJB11
FADD
FAF2
FAS
HSD17B10
IGF2
IKBKB
ITGB1BP1
NGLY1
NLRP12
NLRP2
NLRP3
NLRP7
NR1H2
NR4A1
RAP1A
RAP1B
RCC1
RELA
SIRT6
SKIL
SNIP1
TAF1D
TK1
TNNT1
TSC22D1
UROD
VAPB
Entrez ID
23197
11124
HPRD ID
16870
05124
Ensembl ID
ENSG00000113194
ENSG00000185104
Uniprot IDs
Q96CS3
B4DEJ6
Q9UNN5
PDB IDs
2DAM
1H8C
2DZM
2EC4
3E21
3QC8
3QCA
3QQ8
3QWZ
3QX1
3R3M
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Extrinsic Apoptotic Signaling Pathway
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Cellular Protein Metabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Positive Regulation Of Proteolysis
Regulation Of Protein Metabolic Process
Negative Regulation Of Transferase Activity
Apoptotic Process
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Programmed Cell Death
Cell Death
Death
Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Catalytic Activity
Negative Regulation Of Transcription Factor Import Into Nucleus
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Regulation Of Protein Catabolic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Signal Transduction
Negative Regulation Of Protein Import Into Nucleus
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Negative Regulation Of Protein Localization To Nucleus
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Regulation Of Apoptotic Process
Negative Regulation Of Intracellular Protein Transport
Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Transcription Factor Import Into Nucleus
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Catalytic Activity
Triglyceride Metabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Regulation Of Cell Death
Forebrain Astrocyte Development
Cellular Protein Catabolic Process
Negative Regulation Of Protein Ubiquitination
Extrinsic Apoptotic Signaling Pathway
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Response To Organic Substance
Cellular Response To Organic Substance
Positive Regulation Of Protein Metabolic Process
Regulation Of Catalytic Activity
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Metabolic Process
Regulation Of Metabolic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Signal Transduction
Positive Regulation Of Catalytic Activity
Response To Organic Cyclic Compound
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Apoptotic Process
Regulation Of Cysteine-type Endopeptidase Activity
Regulation Of Apoptotic Process
Positive Regulation Of Hydrolase Activity
Response To Lipid
Regulation Of Cell Death
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Signal Transduction
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Response To Steroid Hormone
Positive Regulation Of Cysteine-type Endopeptidase Activity
Regulation Of Establishment Of Protein Localization
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Endopeptidase Activity
Signal Transduction
Regulation Of Signaling
Positive Regulation Of Peptidase Activity
Regulation Of Endopeptidase Activity
Cellular Response To Mechanical Stimulus
Cellular Response To Organic Cyclic Compound
Regulation Of Peptidase Activity
Response To External Stimulus
Regulation Of Protein Localization
Regulation Of Cellular Localization
Leukocyte Homeostasis
Regulation Of Immune System Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Protein Transport
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Signaling
Activation Of Cysteine-type Endopeptidase Activity
Positive Regulation Of Protein Kinase Activity
Cell Communication
Intracellular Receptor Signaling Pathway
Tagcloud
?
agr
apo
avian
caenorhabditis
carboxy
conjugating
delimited
e0
elegans
executed
fas
fibroblast
helical
homologies
homologue
mesoderm
mutagenesis
pluripotent
portion
potentiates
qfaf
quail
remarkable
resides
shares
transducing
ubiquitous
unusual
Tagcloud (Difference)
?
agr
apo
avian
caenorhabditis
carboxy
conjugating
delimited
e0
elegans
executed
fas
fibroblast
helical
homologies
homologue
mesoderm
mutagenesis
pluripotent
portion
potentiates
qfaf
quail
remarkable
resides
shares
transducing
ubiquitous
unusual
Tagcloud (Intersection)
?