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FAF2
Gene Name
Fas associated factor family member 2
Image
Gene Ontology Annotations
Cellular Component
Endoplasmic Reticulum
Lipid Particle
Cdc48p-Npl4p-Ufd1p AAA ATPase Complex
Intracellular Membrane-bounded Organelle
Molecular Function
Protein Binding
Ubiquitin Protein Ligase Binding
Lipase Binding
Ubiquitin Binding
Lipase Inhibitor Activity
Biological Process
Response To Unfolded Protein
Lipid Particle Organization
Negative Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions
7 interactors:
FAF1
FAS
NF1
PNPLA2
PSMD2
UBE2D1
UBQLN2
Entrez ID
23197
HPRD ID
16870
Ensembl ID
ENSG00000113194
Uniprot IDs
Q96CS3
PDB IDs
2DAM
Enriched GO Terms of Interacting Partners
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Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Extrinsic Apoptotic Signaling Pathway
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Cellular Protein Metabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Positive Regulation Of Proteolysis
Regulation Of Protein Metabolic Process
Negative Regulation Of Transferase Activity
Apoptotic Process
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Programmed Cell Death
Cell Death
Death
Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Catalytic Activity
Negative Regulation Of Transcription Factor Import Into Nucleus
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Regulation Of Protein Catabolic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Signal Transduction
Negative Regulation Of Protein Import Into Nucleus
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Negative Regulation Of Protein Localization To Nucleus
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Regulation Of Apoptotic Process
Negative Regulation Of Intracellular Protein Transport
Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Transcription Factor Import Into Nucleus
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Catalytic Activity
Triglyceride Metabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Regulation Of Cell Death
Forebrain Astrocyte Development
Cellular Protein Catabolic Process
Negative Regulation Of Protein Ubiquitination
Extrinsic Apoptotic Signaling Pathway
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
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