SEPTIN8 and SH3GL1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		SEPTIN8	SH3GL1
Description		septin 8	SH3 domain containing GRB2 like 1, endophilin A2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Septin Ring Microtubule Cytoskeleton Membrane Axon Synaptic Vesicle Membrane Septin Complex Cytoplasmic Vesicle Cell Division Site Cell Projection Synapse Presynapse	Podosome Cytoplasm Endosome Cytosol Membrane Early Endosome Membrane Cell Projection Anchoring Junction Presynapse Glutamatergic Synapse
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Molecular Adaptor Activity	Protein Binding Lipid Binding Identical Protein Binding Cadherin Binding
	Biological Process	Intracellular Protein Localization Regulation Of Protein Stability Regulation Of Intracellular Protein Transport Regulation Of SNARE Complex Assembly Cytoskeleton-dependent Cytokinesis	Endocytosis Signal Transduction Central Nervous System Development
Pathways			EGFR downregulation Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell
Drugs
Diseases
GWAS			Appendicular lean mass ( 33097823) Hematocrit ( 32888494) Red cell distribution width ( 32888494)
Interacting Genes		11 interacting genes: A2M CDK14 ESR1 JADE1 KMT2B PPHLN1 SEPTIN4 SEPTIN5 SH3GL1 SH3GL3 SPTBN1	35 interacting genes: ARHGAP1 ARHGAP8 AXIN1 B3GAT1 CCDC50 CMTM5 CREBBP DNM1 DNM1L DPPA4 DPYSL4 EEIG1 FBXO32 GPKOW ITCH ITSN2 MAL2 MTA1 NUTM2F PDCD6IP PML PRB3 PSMB1 PTPRO RHEX SCAMP5 SEPTIN8 SH2D4A SH3D19 SH3GL3 SOCS1 SPG21 SYNJ1 VPS37C YWHAZ
Entrez ID		23176	6455
HPRD ID		12228	03462
Ensembl ID		ENSG00000164402	ENSG00000141985
Uniprot IDs		A6NFQ9 B7ZVZ1 Q92599	Q6FGM0 Q99961
PDB IDs		6UPR 6WSM
Enriched GO Terms of Interacting Partners?		Cytoskeleton-dependent Cytokinesis Cell Division Site Septin Ring Septin Complex Central Nervous System Development Presynapse Protein Localization To Chromatin	Negative Regulation Of Endocytic Recycling Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cytoplasm Membrane Fission
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