SEPTIN8 and CDK14

Number of citations of the paper that reports this interaction (PubMedID 12098780)
0

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (in vivo, two hybrid)

		SEPTIN8	CDK14
Description		septin 8	cyclin dependent kinase 14
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Septin Ring Microtubule Cytoskeleton Membrane Axon Synaptic Vesicle Membrane Septin Complex Cytoplasmic Vesicle Cell Division Site Cell Projection Synapse Presynapse	Cyclin-dependent Protein Kinase Holoenzyme Complex Cytoplasmic Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Molecular Adaptor Activity	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Cyclin Binding Protein Serine Kinase Activity
	Biological Process	Intracellular Protein Localization Regulation Of Protein Stability Regulation Of Intracellular Protein Transport Regulation Of SNARE Complex Assembly Cytoskeleton-dependent Cytokinesis	G2/M Transition Of Mitotic Cell Cycle Wnt Signaling Pathway Cell Division Regulation Of Canonical Wnt Signaling Pathway Regulation Of Cell Cycle Phase Transition
Pathways
Drugs
Diseases
GWAS			Circulating fibroblast growth factor 23 levels ( 30217807) Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer ( 28429243) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hepatitis B virus-related hepatocellular carcinoma ( 29246937) Pulse pressure ( 30224653 30578418) Serum thyroid-stimulating hormone levels ( 25436638)
Interacting Genes		11 interacting genes: A2M CDK14 ESR1 JADE1 KMT2B PPHLN1 SEPTIN4 SEPTIN5 SH3GL1 SH3GL3 SPTBN1	13 interacting genes: ACVR1 BMPR1B CCND3 CCNY CDKN1A FBXO7 RB1 SEPTIN8 SMURF1 TGFBR1 YWHAB YWHAE YWHAQ
Entrez ID		23176	5218
HPRD ID		12228	15121
Ensembl ID		ENSG00000164402	ENSG00000058091
Uniprot IDs		A6NFQ9 B7ZVZ1 Q92599	B4DK59 E7EUK8 O94921
PDB IDs		6UPR 6WSM
Enriched GO Terms of Interacting Partners?		Cytoskeleton-dependent Cytokinesis Cell Division Site Septin Ring Septin Complex Central Nervous System Development Presynapse Protein Localization To Chromatin	Regulation Of Mitotic Cell Cycle Transforming Growth Factor Beta Receptor Activity, Type I Regulation Of Cell Cycle Cyclin-dependent Protein Kinase Holoenzyme Complex SMAD Binding Transmembrane Receptor Protein Serine/threonine Kinase Activity Mitotic Cell Cycle Phase Transition Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of G1/S Transition Of Mitotic Cell Cycle Cell Cycle Phase Transition Negative Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle G1/S Phase Transition Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Cyclin D3-CDK6 Complex Protein Targeting Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Process Signal Transduction Phosphoprotein Binding Ubiquitin Protein Ligase Binding Protein Sequestering Activity Phosphoserine Residue Binding Negative Regulation Of Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition Activin Receptor Complex Activin Receptor Activity, Type I Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cell Surface Receptor Signaling Pathway Regulation Of Apoptotic Signaling Pathway BMP Receptor Activity Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Developmental Process Positive Regulation Of Cardiac Epithelial To Mesenchymal Transition Positive Regulation Of Metabolic Process Negative Regulation Of Mitotic Cell Cycle Activin Binding Protein Kinase Binding Negative Regulation Of Cell Cycle Phase Transition Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Protein Kinase Activity BMP Signaling Pathway Protein Kinase Activity Regulation Of Kinase Activity Regulation Of Signal Transduction Negative Regulation Of Activin Receptor Signaling Pathway I-SMAD Binding Negative Regulation Of Cell Cycle Process Cellular Response To Growth Factor Stimulus
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