SEPTIN8 and SEPTIN5

Number of citations of the paper that reports this interaction (PubMedID 12909369)
0

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		SEPTIN8	SEPTIN5
Description		septin 8	septin 5
Image
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Septin Ring Microtubule Cytoskeleton Membrane Axon Synaptic Vesicle Membrane Septin Complex Cytoplasmic Vesicle Cell Division Site Cell Projection Synapse Presynapse	Cytoplasm Cytoskeleton Plasma Membrane Septin Ring Synaptic Vesicle Microtubule Cytoskeleton Septin Complex Cell Division Site
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Molecular Adaptor Activity	Nucleotide Binding GTPase Activity Structural Molecule Activity Protein Binding GTP Binding Identical Protein Binding Molecular Adaptor Activity
	Biological Process	Intracellular Protein Localization Regulation Of Protein Stability Regulation Of Intracellular Protein Transport Regulation Of SNARE Complex Assembly Cytoskeleton-dependent Cytokinesis	Intracellular Protein Localization Synaptic Vesicle Targeting Regulation Of Exocytosis Adult Behavior Social Behavior Cell Division Cytoskeleton-dependent Cytokinesis Regulation Of Synaptic Vesicle Exocytosis
Pathways
Drugs
Diseases
GWAS
Interacting Genes		11 interacting genes: A2M CDK14 ESR1 JADE1 KMT2B PPHLN1 SEPTIN4 SEPTIN5 SH3GL1 SH3GL3 SPTBN1	21 interacting genes: APP CDK5R1 DDIT4L KAT7 KIDINS220 LSM8 MAGEA2 MAGEA2B MAPK6 MYOG PFN2 PLEKHF2 PRKN SEPTIN1 SEPTIN2 SEPTIN4 SEPTIN7 SEPTIN8 SPG21 STX1A STX4
Entrez ID		23176	5413
HPRD ID		12228	04100
Ensembl ID		ENSG00000164402	ENSG00000184702
Uniprot IDs		A6NFQ9 B7ZVZ1 Q92599	Q99719 X5DNA9
PDB IDs		6UPR 6WSM	6WCU
Enriched GO Terms of Interacting Partners?		Cytoskeleton-dependent Cytokinesis Cell Division Site Septin Ring Septin Complex Central Nervous System Development Presynapse Protein Localization To Chromatin	Septin Ring Septin Complex Cell Division Site Sperm Annulus Cytoskeleton-dependent Cytokinesis Regulation Of Exocytosis Regulation Of Vesicle-mediated Transport Molecular Adaptor Activity Presynapse Axon Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Protein Localization Positive Regulation Of Protein Ubiquitination Negative Regulation Of Protein Acetylation Microtubule Cytoskeleton Regulation Of Spontaneous Synaptic Transmission Synaptic Vesicle Positive Regulation Of Post-translational Protein Modification Modulation Of Excitatory Postsynaptic Potential Regulation Of Establishment Of Protein Localization GTPase Activity Cellular Response To Manganese Ion Neuron Projection Regulation Of Secretion By Cell Negative Regulation Of Protein Sumoylation Regulation Of Transport GTP Binding Regulation Of Intrinsic Apoptotic Signaling Pathway Cell Projection Regulation Of Secretion Positive Regulation Of Protein Modification Process Regulation Of Protein Ubiquitination SNARE Complex Assembly Regulation Of Apoptotic Signaling Pathway Synapse Regulation Of Protein Modification Process Positive Regulation Of Ubiquitin-protein Transferase Activity Dopaminergic Synapse Regulation Of Amine Transport Response To Manganese Ion Intracellular Protein Localization Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Neurotransmitter Secretion Regulation Of Protein Transport Postsynapse Collateral Sprouting Cellular Response To Catecholamine Stimulus Regulation Of Post-translational Protein Modification Neurotransmitter Transport Schaffer Collateral - CA1 Synapse
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