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MAPK8IP3 and MAPK8IP1
Number of citations of the paper that reports this interaction (PMID
10629060
)
49
Data Source:
BioGRID
(pull down)
HPRD
(in vitro)
MAPK8IP3
MAPK8IP1
Gene Name
mitogen-activated protein kinase 8 interacting protein 3
mitogen-activated protein kinase 8 interacting protein 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Cytoplasm
Smooth Endoplasmic Reticulum
Dendrite
Axolemma
Nucleus
Cytoplasm
Endoplasmic Reticulum Membrane
Cytosol
Mitochondrial Membrane
Dendritic Growth Cone
Axonal Growth Cone
Cell Body
Dentate Gyrus Mossy Fiber
Synapse
Perinuclear Region Of Cytoplasm
Molecular Function
MAP-kinase Scaffold Activity
JUN Kinase Binding
Kinesin Binding
Receptor Signaling Complex Scaffold Activity
Mitogen-activated Protein Kinase Kinase Binding
Mitogen-activated Protein Kinase Kinase Kinase Binding
Protein Kinase Inhibitor Activity
MAP-kinase Scaffold Activity
Protein Binding
JUN Kinase Binding
Kinesin Binding
Mitogen-activated Protein Kinase Kinase Binding
Mitogen-activated Protein Kinase Kinase Kinase Binding
Identical Protein Binding
Biological Process
In Utero Embryonic Development
Activation Of JUN Kinase Activity
Axon Guidance
Respiratory Gaseous Exchange
Protein Localization
Post-embryonic Development
Regulation Of Gene Expression
Vesicle-mediated Transport
Forebrain Development
Positive Regulation Of Neuron Differentiation
Regulation Of JNK Cascade
Lung Alveolus Development
Lung Morphogenesis
Regulation Of Transcription, DNA-templated
JUN Phosphorylation
Positive Regulation Of Signal Transduction
Vesicle-mediated Transport
Negative Regulation Of JUN Kinase Activity
Regulation Of JNK Cascade
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
21 interactors:
ARL4D
CASP3
KLC1
KLC2
MAP2K1
MAP2K4
MAP2K7
MAP3K11
MAP3K5
MAPK10
MAPK8
MAPK8IP1
MAPK8IP2
MAPK9
PTK2
RAF1
RIC8A
SRC
TLR2
TLR4
TLR9
25 interactors:
AKT1
APP
ARHGEF28
DUSP16
EGFR
ERBB2
KLC1
LRP1
LRP2
LRP8
MAP2K7
MAP3K10
MAP3K11
MAP3K12
MAP3K13
MAP3K7
MAPK8
MAPK8IP2
MAPK8IP3
MAPK9
PAX2
RECQL5
SNCA
TIAM1
VRK2
Entrez ID
23162
9479
HPRD ID
12014
05223
Ensembl ID
ENSG00000138834
ENSG00000121653
Uniprot IDs
E9PFH7
Q9UPT6
E9PBB9
Q6NUQ9
Q9UQF2
PDB IDs
2G01
2GMX
2H96
3OXI
3PTG
3VUD
3VUG
3VUH
3VUI
3VUK
3VUL
3VUM
4E73
4G1W
4H39
Enriched GO Terms of Interacting Partners
?
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
MyD88-dependent Toll-like Receptor Signaling Pathway
MAPK Cascade
JNK Cascade
Positive Regulation Of Signal Transduction
Regulation Of Protein Kinase Activity
Signal Transduction By Phosphorylation
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Regulation Of Kinase Activity
Toll-like Receptor Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Regulation Of Stress-activated MAPK Cascade
Regulation Of Protein Phosphorylation
Regulation Of MAPK Cascade
Immune Response-regulating Signaling Pathway
Positive Regulation Of Protein Kinase Activity
Intracellular Signal Transduction
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Positive Regulation Of Kinase Activity
Positive Regulation Of Catalytic Activity
Positive Regulation Of Protein Metabolic Process
Activation Of Innate Immune Response
Toll-like Receptor 4 Signaling Pathway
Positive Regulation Of Protein Phosphorylation
Protein Phosphorylation
Regulation Of Phosphorylation
Positive Regulation Of Transferase Activity
Regulation Of JNK Cascade
Regulation Of Protein Metabolic Process
Innate Immune Response
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of MAP Kinase Activity
Response To Stress
Positive Regulation Of Innate Immune Response
Phosphorylation
Positive Regulation Of MAPK Cascade
Positive Regulation Of Phosphorylation
Regulation Of Phosphorus Metabolic Process
Regulation Of Catalytic Activity
Positive Regulation Of Protein Modification Process
Toll-like Receptor 9 Signaling Pathway
Regulation Of Cellular Protein Metabolic Process
TRIF-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of MAP Kinase Activity
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
JNK Cascade
Regulation Of Catalytic Activity
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Signal Transduction By Phosphorylation
Regulation Of Protein Kinase Activity
Positive Regulation Of Catalytic Activity
Regulation Of Kinase Activity
MAPK Cascade
Regulation Of MAPK Cascade
Positive Regulation Of Protein Kinase Activity
Regulation Of Phosphorylation
Regulation Of Protein Phosphorylation
Positive Regulation Of Kinase Activity
Positive Regulation Of Protein Phosphorylation
Regulation Of Phosphorus Metabolic Process
Regulation Of Signaling
Positive Regulation Of Transferase Activity
Regulation Of Signal Transduction
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Phosphorylation
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Modification Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Protein Metabolic Process
Response To Stress
Regulation Of Intracellular Signal Transduction
Phosphorylation
Intracellular Signal Transduction
Cellular Response To Stress
Regulation Of JNK Cascade
Positive Regulation Of Protein Serine/threonine Kinase Activity
Positive Regulation Of Metabolic Process
Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of MAPK Cascade
Signaling
Cellular Response To Stimulus
Cell Communication
Protein Autophosphorylation
Response To Light Stimulus
Activation Of MAPKK Activity
Positive Regulation Of Signal Transduction
Signal Transduction
Phosphate-containing Compound Metabolic Process
Protein Phosphorylation
Response To Stimulus
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Activation Of Protein Kinase Activity
Positive Regulation Of Cellular Metabolic Process
Tagcloud
?
advantage
alleles
cited
curative
cure
curves
deemed
ductal
facilitated
genotyped
hazards
kaplan
locally
meier
metastatic
minor
noncarriers
pc
polymorphisms
resected
rs1124736
rs3824872
rs8064821
snp
snps
socs3
tag
unresected
worse
Tagcloud (Difference)
?
advantage
alleles
cited
curative
cure
curves
deemed
ductal
facilitated
genotyped
hazards
kaplan
locally
meier
metastatic
minor
noncarriers
pc
polymorphisms
resected
rs1124736
rs3824872
rs8064821
snp
snps
socs3
tag
unresected
worse
Tagcloud (Intersection)
?