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MAPK8IP3 and ARL4D
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
MAPK8IP3
ARL4D
Gene Name
mitogen-activated protein kinase 8 interacting protein 3
ADP-ribosylation factor-like 4D
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Cytoplasm
Smooth Endoplasmic Reticulum
Dendrite
Axolemma
Nucleolus
Cytoplasm
Plasma Membrane
Molecular Function
MAP-kinase Scaffold Activity
JUN Kinase Binding
Kinesin Binding
Receptor Signaling Complex Scaffold Activity
Mitogen-activated Protein Kinase Kinase Binding
Mitogen-activated Protein Kinase Kinase Kinase Binding
GTPase Activity
Protein Binding
GTP Binding
Biological Process
In Utero Embryonic Development
Activation Of JUN Kinase Activity
Axon Guidance
Respiratory Gaseous Exchange
Protein Localization
Post-embryonic Development
Regulation Of Gene Expression
Vesicle-mediated Transport
Forebrain Development
Positive Regulation Of Neuron Differentiation
Regulation Of JNK Cascade
Lung Alveolus Development
Lung Morphogenesis
Small GTPase Mediated Signal Transduction
Metabolic Process
Protein Secretion
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
21 interactors:
ARL4D
CASP3
KLC1
KLC2
MAP2K1
MAP2K4
MAP2K7
MAP3K11
MAP3K5
MAPK10
MAPK8
MAPK8IP1
MAPK8IP2
MAPK9
PTK2
RAF1
RIC8A
SRC
TLR2
TLR4
TLR9
21 interactors:
APP
ARL6IP1
CCDC102B
CNPY4
DNAJA1
EIF2B1
EML4
EPRS
MAPK8IP3
NDRG1
PGAM1
PRKCSH
SMAD1
SMAD2
SMURF1
SNRPN
TGFBR1
TLE1
TMEM230
UBR1
UNC119
Entrez ID
23162
379
HPRD ID
12014
02842
Ensembl ID
ENSG00000138834
ENSG00000175906
Uniprot IDs
E9PFH7
Q9UPT6
P49703
PDB IDs
Enriched GO Terms of Interacting Partners
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Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
MyD88-dependent Toll-like Receptor Signaling Pathway
MAPK Cascade
JNK Cascade
Positive Regulation Of Signal Transduction
Regulation Of Protein Kinase Activity
Signal Transduction By Phosphorylation
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Regulation Of Kinase Activity
Toll-like Receptor Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Regulation Of Stress-activated MAPK Cascade
Regulation Of Protein Phosphorylation
Regulation Of MAPK Cascade
Immune Response-regulating Signaling Pathway
Positive Regulation Of Protein Kinase Activity
Intracellular Signal Transduction
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Positive Regulation Of Kinase Activity
Positive Regulation Of Catalytic Activity
Positive Regulation Of Protein Metabolic Process
Activation Of Innate Immune Response
Toll-like Receptor 4 Signaling Pathway
Positive Regulation Of Protein Phosphorylation
Protein Phosphorylation
Regulation Of Phosphorylation
Positive Regulation Of Transferase Activity
Regulation Of JNK Cascade
Regulation Of Protein Metabolic Process
Innate Immune Response
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of MAP Kinase Activity
Response To Stress
Positive Regulation Of Innate Immune Response
Phosphorylation
Positive Regulation Of MAPK Cascade
Positive Regulation Of Phosphorylation
Regulation Of Phosphorus Metabolic Process
Regulation Of Catalytic Activity
Positive Regulation Of Protein Modification Process
Toll-like Receptor 9 Signaling Pathway
Regulation Of Cellular Protein Metabolic Process
TRIF-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of MAP Kinase Activity
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Transforming Growth Factor Beta Receptor Signaling Pathway
Primary MiRNA Processing
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Cellular Response To Stimulus
Posttranscriptional Regulation Of Gene Expression
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Cell Development
Response To Stimulus
Response To Organic Substance
SMAD Protein Complex Assembly
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Renal System Development
Negative Regulation Of Signal Transduction
Neurogenesis
Production Of MiRNAs Involved In Gene Silencing By MiRNA
Response To Cholesterol
Post-embryonic Development
Urogenital System Development
Negative Regulation Of Signaling
Regulation Of Protein Kinase Activity
Regulation Of Kinase Activity
Activin Receptor Signaling Pathway
Cell Differentiation
Gene Silencing By MiRNA
Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of Cellular Protein Metabolic Process
Signal Transduction
Cellular Response To DsRNA
Response To Stress
Cellular Protein Metabolic Process
Posttranscriptional Gene Silencing
In Utero Embryonic Development
Regulation Of Signal Transduction
Regulation Of Phosphorus Metabolic Process
Regulation Of Neuron Differentiation
Regulation Of Cellular Process
Regulation Of Protein Metabolic Process
Signaling
Regulation Of Cell Differentiation
Regulation Of Epithelial To Mesenchymal Transition
Cellular Response To Growth Factor Stimulus
RNA Processing
Negative Regulation Of Clathrin-mediated Endocytosis
Regulation Of Pentose-phosphate Shunt
Cell Communication
Nervous System Development
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Tagcloud (Intersection)
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