EPB41L3 and ATXN1L

Number of citations of the paper that reports this interaction (PubMedID 16713569)
0

Data Source:
BioGRID (two hybrid)

		EPB41L3	ATXN1L
Description		erythrocyte membrane protein band 4.1 like 3	ataxin 1 like
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cell-cell Junction Cilium Membrane Cell Junction Axolemma Paranode Region Of Axon Ciliary Basal Body Juxtaparanode Region Of Axon Anchoring Junction Postsynapse Glutamatergic Synapse	Nucleus Nucleoplasm Nucleolus Dendrite Cell Projection
	Molecular Function	Actin Binding Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Protein Binding Cytoskeletal Protein-membrane Anchor Activity	DNA Binding Chromatin Binding RNA Binding Protein Binding POZ Domain Binding
	Biological Process	Protein Localization To Paranode Region Of Axon Apoptotic Process Biological_process Regulation Of Cell Shape Cortical Cytoskeleton Organization Cortical Actin Cytoskeleton Organization Paranodal Junction Assembly Actomyosin Structure Organization Myelin Maintenance Neuron Projection Morphogenesis Protein Localization To Juxtaparanode Region Of Axon Protein Localization To Plasma Membrane Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Transcription By RNA Polymerase II Brain Development Learning Memory Extracellular Matrix Organization Social Behavior Lung Alveolus Development Positive Regulation Of Hematopoietic Stem Cell Proliferation
Pathways		Neurexins and neuroligins Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases
GWAS		Cerebral amyloid deposition (PET imaging) ( 26252872) Chronic kidney disease ( 31152163) Diverticular disease ( 30177863) Estimated glomerular filtration rate ( 30604766 31015462 31152163 31451708) Glomerular filtration rate (creatinine) ( 28452372) Lacunar stroke ( 33773637) Optic nerve head parameters (multi-trait analysis) ( 31798171) Sleep duration ( 25469926) Social communication problems ( 24564958) Thyroid nodules ( 30099483) Vertical cup-disc ratio ( 31798171)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Response to anti-TNF therapy in rheumatoid arthritis ( 26776603) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		20 interacting genes: ATXN1L CADM1 CEP152 CLNS1A CNTNAP2 HSPB1 IGSF21 MBIP MECOM PAXIP1 PSEN1 SPANXN2 SPTBN1 TCF4 UNC13A YWHAB YWHAG YWHAH YWHAQ YWHAZ	83 interacting genes: ACO2 ACOT7 ADORA1 AFAP1L2 AGXT ALG13 ANKHD1 AP1G2 AP2M1 APBB1 ARID5A ATXN1 C1orf94 CAMSAP2 CBFA2T2 CDSN CHD6 COIL CTBP1 DAB2 DAZAP2 EPB41L2 EPB41L3 FADS2 FAM168A FOXH1 FUS GAS7 GMEB2 GORASP2 GPATCH8 HGS HIVEP1 HLX HSFX1 KRTAP11-1 KRTAP13-1 KRTAP19-7 KRTAP21-2 KRTAP8-1 LARP4B MACROH2A1 MATN2 MBD1 MBD6 MEIS3 MEOX2 METTL17 METTL27 MYOZ3 NBR1 NCOR1 NCOR2 NIT1 NUTM2F PHPT1 PICALM PICK1 PRRC2B RAD54L2 RBFOX1 RBFOX2 RRAGC SCAF11 SHISA2 SMARCC2 SPMIP9 SREBF1 ST6GALNAC6 STAC2 SUGP2 TBX2 THY1 TMEM25 TMEM8B TRIP11 UNKL USP54 YPEL3 YY1AP1 ZBTB32 ZC3H7B ZSWIM8
Entrez ID		23136	342371
HPRD ID		05622	19555
Ensembl ID		ENSG00000082397	ENSG00000224470
Uniprot IDs		A0A0A0MRA8 A8K968 Q9Y2J2	P0C7T5
PDB IDs		2HE7 3BIN 5RYM 5RYN 5RYO 5RYP 5RYQ 5RYR 5RYS 5RYT 5RYU 5RYV 5RYW 5RYX 5RYY 5RYZ 5RZ0 5RZ1 5RZ2 5RZ3 5RZ4 5RZ5 5RZ6 5RZ7 5RZ8 5RZ9 5RZA 5RZB 5RZC 5RZD 5RZE 5RZF 5RZG 5RZH 5RZI 5RZJ 5RZK 5RZL 5RZM 5RZN 5RZO 5RZP 5RZQ 5RZR 5RZS 5RZT 5RZU 5RZV 5RZW 5RZX 5RZY 5RZZ 5S00 6IBE
Enriched GO Terms of Interacting Partners?		Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Protein Kinase C Inhibitor Activity Protein Domain Specific Binding Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Presynaptic Membrane Phosphoserine Residue Binding Protein Sequestering Activity Transmembrane Transporter Binding Regulation Of Macromolecule Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Macromolecule Metabolic Process Establishment Of Protein Localization Synapse Protein Targeting Axolemma Intracellular Protein Localization Regulation Of Metabolic Process Focal Adhesion Insulin-like Growth Factor Receptor Binding Positive Regulation Of Metabolic Process Modulation Of Chemical Synaptic Transmission Regulation Of Primary Metabolic Process Cell Recognition Glutamatergic Synapse Cadherin Binding Positive Regulation Of Lymphocyte Mediated Immunity Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Identical Protein Binding Negative Regulation Of Biosynthetic Process Regulation Of Protein Localization To Nucleus Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process Regulation Of Cell Communication Regulation Of Signaling Negative Regulation Of Protein Kinase C Signaling Negative Regulation Of Core Promoter Binding Transferase Activity, Transferring One-carbon Groups Thymidylate Synthase Activity Glucocorticoid Catabolic Process Regulation Of Developmental Process Protein Kinase Inhibitor Activity Substantia Nigra Development Neuron Recognition Protein Kinase C Binding Regulation Of Neuron Differentiation Negative Regulation Of Protein Localization To Nucleus	Negative Regulation Of Androgen Receptor Signaling Pathway Low-density Lipoprotein Particle Receptor Binding Regulation Of Androgen Receptor Signaling Pathway Axolemma Chromatin Binding Negative Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Clathrin Adaptor Activity Regulation Of Protein Localization To Cell Periphery Transcription Corepressor Activity Clathrin Coat Assembly Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Nuclear Body Positive Regulation Of Response To Oxidative Stress Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Extrinsic Component Of Presynaptic Endocytic Zone Membrane Double-stranded Methylated DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Negative Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of 3'-UTR-mediated MRNA Stabilization Regulation Of Protein Localization Clathrin-coated Pit Clathrin-dependent Endocytosis Sequence-specific DNA Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Protein Localization Chromatin Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process
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