EPB41L3 and SPTBN1

Number of citations of the paper that reports this interaction (PMID 15116094)
2

Data Source:
BioGRID (pull down)

		EPB41L3	SPTBN1
Gene Name		erythrocyte membrane protein band 4.1-like 3	spectrin, beta, non-erythrocytic 1
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Cell-cell Junction Extrinsic Component Of Membrane Axolemma Paranode Region Of Axon Juxtaparanode Region Of Axon	Nucleolus Cytoplasm Cytosol Spectrin Spectrin-associated Cytoskeleton Axolemma M Band Cuticular Plate Protein Complex Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Calmodulin Binding Phospholipid Binding Ankyrin Binding Protein Complex Binding Poly(A) RNA Binding
	Biological Process	Protein Localization To Paranode Region Of Axon Apoptotic Process Cytoskeletal Anchoring At Plasma Membrane Biological_process Regulation Of Cell Shape Cortical Cytoskeleton Organization Cortical Actin Cytoskeleton Organization Paranodal Junction Assembly Myelin Maintenance Neuron Projection Morphogenesis Protein Localization To Juxtaparanode Region Of Axon Protein Localization To Plasma Membrane	Mitotic Cytokinesis Plasma Membrane Organization Common-partner SMAD Protein Phosphorylation SMAD Protein Import Into Nucleus Axon Guidance Golgi To Plasma Membrane Protein Transport Actin Filament Capping Membrane Assembly Protein Targeting To Plasma Membrane
Pathways			Interaction between L1 and Ankyrins Axon guidance Nephrin interactions L1CAM interactions NCAM signaling for neurite out-growth
Drugs
Diseases
GWAS			Bone mineral density ( 22504420) Bone mineral density (spine) ( 19079262 19801982 18445777) Myopia (pathological) ( 22685421)
Protein-Protein Interactions		17 interactors: ATXN1L CADM1 CEP152 CLNS1A CNTNAP2 IGSF21 MBIP PAXIP1 PSEN1 SPTBN1 TCF4 UNC13A YWHAB YWHAG YWHAH YWHAQ YWHAZ	39 interactors: ACTR1A ANK2 APC ATF7IP CAPN1 CDC5L CEP63 CPNE1 CPNE4 CSNK2A1 CTNNA1 DISC1 EPB41 EPB41L3 GRB2 GRIA2 MAPK14 MEF2C NF2 PACSIN1 PDE4D PJA1 PLCB1 PLEKHA5 PRKACA PYGO1 RINT1 SH3BP5 SMAD3 SMAD4 SMAD9 SNCA SPTAN1 SREBF2 STAT1 TNIK TRAF3IP1 YWHAG ZNF512B
Entrez ID		23136	6711
HPRD ID		05622	01683
Ensembl ID		ENSG00000082397	ENSG00000115306
Uniprot IDs		A8K968 B7Z4I5 F5GX05 Q9Y2J2	B2ZZ89 Q01082
PDB IDs		2HE7 3BIN	1AA2 1BKR 3EDV
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Positive Regulation Of Intracellular Transport Positive Regulation Of Transport Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Cellular Localization Intrinsic Apoptotic Signaling Pathway Regulation Of Establishment Of Protein Localization Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Organelle Organization Protein Targeting Regulation Of Intracellular Transport Nervous System Development Regulation Of Protein Localization Cellular Localization Membrane Organization System Development Cellular Protein Localization Protein Localization Intracellular Protein Transport Regulation Of Organelle Organization Regulation Of Cellular Component Organization Protein Transport Establishment Of Localization In Cell Apoptotic Process Establishment Of Protein Localization Programmed Cell Death Intracellular Transport Apoptotic Signaling Pathway Cell Death Death Multicellular Organismal Development Regulation Of Synaptic Plasticity Anatomical Structure Development Brain Development Head Development Positive Regulation Of Signal Transduction Intracellular Signal Transduction Cellular Component Assembly Developmental Process Regulation Of Apoptotic Process Central Nervous System Development Regulation Of Cell Death Generation Of Neurons Regulation Of Synaptic Transmission	Regulation Of Cellular Component Organization System Development Intracellular Signal Transduction Nervous System Development Regulation Of Cellular Localization Cell Differentiation Positive Regulation Of Cell Differentiation Regulation Of Cell Differentiation Regulation Of Phosphorylation Regulation Of Signal Transduction Multicellular Organismal Development Anatomical Structure Development Cell-cell Junction Organization Regulation Of Intracellular Transport Developmental Process Regulation Of Phosphorus Metabolic Process Negative Regulation Of Protein Phosphorylation Positive Regulation Of Signal Transduction Regulation Of Signaling Regulation Of Protein Phosphorylation Neurogenesis Negative Regulation Of Phosphorylation Apoptotic Process Signaling Anatomical Structure Morphogenesis Negative Regulation Of Cellular Metabolic Process Cell Development Organelle Organization Programmed Cell Death Cell Communication Generation Of Neurons Kidney Development Cell Death Cell Morphogenesis Death Regulation Of Protein Metabolic Process Cell-cell Junction Assembly Epithelium Development Cellular Response To Organonitrogen Compound Renal System Development Cell Activation Organ Development Regulation Of Cellular Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Protein Metabolic Process Cell Projection Organization Regulation Of Organelle Organization Positive Regulation Of Metabolic Process G2/M Transition Of Mitotic Cell Cycle Neuron Development
Tagcloud ?			adipocyte analyzing classified cytoskeletal differentially exposed exposure fact fatty insights k18 keratin mediating morphogenesis nicotine obstructive osf3 peroxiredoxin phosphoprotein phosphoproteins phosphoproteomic regeneration semi sixteen smoke sought spectrin spt16 tobacco
Tagcloud (Difference) ?			adipocyte analyzing classified cytoskeletal differentially exposed exposure fact fatty insights k18 keratin mediating morphogenesis nicotine obstructive osf3 peroxiredoxin phosphoprotein phosphoproteins phosphoproteomic regeneration semi sixteen smoke sought spectrin spt16 tobacco
Tagcloud (Intersection) ?