MYCBP2 and CDC14B

		MYCBP2	CDC14B
Description		MYC binding protein 2	cell division cycle 14B
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Microtubule Cytoskeleton Membrane Axon Cell Projection	Spindle Pole Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Cell Junction Mitotic Spindle
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Transferase Activity Small GTPase Binding Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Hydrolase Activity
	Biological Process	Axon Guidance Motor Neuron Axon Guidance Regulation Of Synaptic Assembly At Neuromuscular Junction Protein Ubiquitination Branchiomotor Neuron Axon Guidance Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Protein Ubiquitination Regulation Of Protein Localization Circadian Regulation Of Gene Expression Negative Regulation Of Protein Catabolic Process Rhythmic Process Cell Morphogenesis Involved In Neuron Differentiation Neuromuscular Process Regulation Of Cytoskeleton Organization Axon Development Protein K48-linked Ubiquitination Regulation Of Axon Guidance	Microtubule Cytoskeleton Organization DNA Repair Protein Dephosphorylation DNA Damage Response Mitotic G2 DNA Damage Checkpoint Signaling Regulation Of Exit From Mitosis Positive Regulation Of Cytokinesis Cilium Assembly Positive Regulation Of Ubiquitin Protein Ligase Activity
Pathways			MAPK6/MAPK4 signaling
Drugs
Diseases
GWAS		Chronotype ( 30696823) Iris heterochromicity ( 30895295) Morning person ( 30696823) Preeclampsia ( 23551011) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)	Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Household income ( 31844048) Intelligence (MTAG) ( 29326435) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		50 interacting genes: AATF APPL1 ARL6IP5 ASB8 ATP13A2 BTG3 CALM1 CD81 CEBPA CFL1 CUEDC2 DHRS4L2 DSCR9 DYRK1A ERBB3 FHL3 FSCN1 HSP90AB1 HUNK IGFBP6 LCOR LDHB LSM14A MYC NDUFB9 NMNAT2 OAZ1 PABPN1 PI4KB PRXL2A PTPN12 PUF60 RGPD8 RPS5 RSPH1 SERPINB6 SOD1 SPARCL1 SPRYD3 SRPK2 TBC1D9 TBC1D9B TBR1 TTN UBE2D2 UBE2D3 UBE2L3 UCHL1 YWHAG YWHAQ	20 interacting genes: BCL10 BUB1 CCND1 CDKN2A CHEK1 DLC1 MCC MFAP1 MLH3 MSH2 MTDH PRKAB2 PSMB1 SIRT2 SKP2 SMAD4 SPANXN2 STK11 TP53 ZNF696
Entrez ID		23077	8555
HPRD ID		10104	04615
Ensembl ID		ENSG00000005810	ENSG00000081377
Uniprot IDs		O75592	A0A9L9PY50 O60729
PDB IDs		5O6C 6T7F	1OHC 1OHD 1OHE
Enriched GO Terms of Interacting Partners?		Cytoplasm Intracellular Signal Transduction	Nucleus Nucleoplasm Regulation Of Cell Cycle Phase Transition Replicative Senescence Mitotic DNA Integrity Checkpoint Signaling Regulation Of Apoptotic Process Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Mitotic DNA Damage Checkpoint Signaling Regulation Of Cell Cycle Apoptotic Signaling Pathway Positive Regulation Of Execution Phase Of Apoptosis Regulation Of Programmed Cell Death Negative Regulation Of Cell Cycle Response To X-ray Negative Regulation Of Mitotic Cell Cycle DNA Damage Checkpoint Signaling Negative Regulation Of Cell Cycle Phase Transition NF-kappaB Binding Regulation Of Cell Population Proliferation Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Cell Cycle Process Negative Regulation Of Cell Cycle Process Intracellular Signal Transduction Negative Regulation Of Cell Population Proliferation Positive Regulation Of Post-translational Protein Modification Centromeric DNA Binding Response To Ionizing Radiation Signal Transduction In Response To DNA Damage Positive Regulation Of Apoptotic Process Response To UV Positive Regulation Of Programmed Cell Death Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Cell Growth Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Catabolic Process Positive Regulation Of Protein Modification Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Mismatched DNA Binding Regulation Of Protein Ubiquitination P53 Binding Regulation Of Protein Modification Process MDM2/MDM4 Family Protein Binding General Transcription Initiation Factor Binding Centrosome Negative Regulation Of Growth Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Cellular Component Organization Mitotic G1 DNA Damage Checkpoint Signaling Mammary Gland Epithelial Cell Proliferation
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